U.S. Department of Health and Human Services
Staff Search  
​​

If you plan to apply, Register Early.

Registration is required at eRA Commons and grants.gov and can take 4 weeks.​

Endocrine Pancreas

The Endocrine Pancreas program supports research on the basic biology, development, and function of the endocrine pancreas, as well as clinical studies on islet transplantation for the treatment of type 1 diabetes.  The research in this program includes developmental biology studies on tissue formation, particularly the development and regeneration of pancreatic islets, and basic biology studies on hormone synthesis and secretion from pancreatic endocrine cells (alpha, beta, delta, etc.) within the islet.  Areas addressing islet transplantation include studies on optimizing islet yield, viability, and durability in the procurement and pre-transplant process; enhancing islet graft survival and promoting immune tolerance of islet grafts; and evaluating transplantation alternatives to human islets.  ​​​​​​​​​​

​​​​​​​​​​​​​​​​​​
 

 NIDDK Staff

 
Michael C. Appel, Ph.D.Basic biology of the endocrine pancreas, beta cell and islet function, and bioengineering and transplantation of isletsGuillermo A. Arreaza-Rubin, M.D.Diabetes and endocrine disease bioengineering and glucose sensingOlivier Blondel, Ph.D.Pathophysiology of the endocrine pancreas in diabetes; technology development (i.e. genomics and systems biology) in metabolic diseaseThomas Eggerman, M.D., Ph.D.Cystic fibrosis research and translation centers, clinical trials, and islet transplantation
Barbara Linder, M.D., Ph.D.Type 2 diabetes in children and youth; glycemic reduction approaches and hypoglycemia during pregnancy; metabolic imprintingSheryl Sato, Ph.D.Basic mechanisms underlying the organogenesis and regeneration of pancreatic islets during health and diseaseJose Serrano, M.D., Ph.D.Liver Bioengineering and Biotechnology; Cell and Molecular Biology of the Liver; Developmental Biology and Regeneration; Drug-induced Liver Disease; Gastrointestinal Neuroendocrinology; Exocrine Pancreas; Pancreatitis

 

 Related Funding Opportunities

 
Posted DateTitleFull Announcement
7/21/2014Advanced Clinical Trials to test Artificial Pancreas Device Systems in Type 1 Diabetes (UC4) (Summary) RFA-DK-14-024
7/17/2014High Throughput Screening (HTS) to Discover Chemical Probes (R01) (Summary) PAR-14-284
7/2/2014Innovative Therapies and Tools for Screenable Disorders in Newborns (R01) (Summary) PAR-14-270
7/2/2014NIAID SBIR - Technology Transfer Direct Phase II (SBIR-TT) (R44) - See more at: http://grants.nih.gov/grants/guide/rfa-files/RFA-AI-14-049.html#sthash.5IEWBI1W.dpuf (Summary) RFA-AI-14-049
6/25/2014NIDDK Mentored Research Scientist Development Award (K01) (Summary) PAR-14-266
View More Funding Opportunities

​The resources listed below include reagents, data, protocols, etc.  If you would like to utilize any of these resources, contact the person associated with the resource.
 

 Research Resources

 
Resource NameDescription
Type 1 Diabetes-Rapid Access to Intervention Development
Type 1 Diabetes-Rapid Access to Intervention Development (T1D-RAID): T1D-RAID is not accepting new applications at this time, but currently supports ongoing projects. The goal of T1D-RAID is … (Summary)
Hyperglycemia and Pregnancy Outcomes Follow-Up Study Consortium

The goal of this follow-up study of mothers who participated in the Hyperglycemia and Adverse Pregnancy Outcomes (HAPO) study, is to determine the levels of blood sugar during pregnancy that … (Summary)

Diabetes Prevention Program
The DPP showed that lifestyle change or metformin delay the development of type 2 diabetes. The DPPOS is a long-term follow-up study of the DPP participants.
(Summary)
Diabetes Prevention Program Outcomes Study
The Diabetes Prevention Program Outcomes Study is studying the long term effect of diet and exercise and the diabetes medication, metformin, on the delay of type 2 diabetes in participants of … (Summary)
NIDDK Information Network

The NIDDK Information Network (dkNET), serves the needs of basic and clinical investigators by providing seamless access to large pools of data relevant to the mission of NIDDK. The goal of … (Summary)

View Additional Research Resources

 

 NIDDK Active Trials in Type 1 Diabetes

 
View related clinical trials from ClinicalTrials.gov.

 

 Related Study Sections

 
​​Study sections conduct initial peer review of applications in a designated scientific area. View related study sections from the NIH's Center for Scientific Review.