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Erythropoiesis and Hemoglobin

The Erythropoiesis and Hemoglobin program supports work on the molecular and cellular biological pathways involved in erythroid cell differentiation.  This includes not only adult or definitive erythropoiesis (differentiation), but also ontological or primitive erythropoiesis (development).  Specific areas of interest include:  transcriptional, post-transcriptional, and translational regulation of erythroid-specific genes; mechanisms underlying normal and disordered globin gene regulation; heme biosynthesis and iron metabolism during erythropoiesis; erythroid cell membrane structure and function and the interaction of transport and receptor molecules; erythropoietin receptor signaling and its effects on gene regulation; mechanistic determinants of red blood cell survival; detection of abnormal hemoglobins; development of genetically targeted therapies for sickle cell anemia and thalassemias; and development of clinically applicable approaches for controlling fetal versus adult b-globin gene expression.​​
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 NIDDK Staff

 
Terry Rogers Bishop, Ph.D.Hematology; Hematology Centers; Hematology Training

 

 Related Funding Opportunities

 
Posted DateTitleFull Announcement
9/4/2014Advancing Interventions to Improve Medication Adherence (R01) (Summary) PA-14-334
7/30/2014NIDDK Central Repositories Non-renewable Sample Access (X01) (Summary) PAR-14-301
7/29/2014NIDDK Clinician Scientist Mentoring Award to Promote Workforce Diversity (K05) (Summary) RFA-DK-14-005
7/17/2014High Throughput Screening (HTS) to Discover Chemical Probes (R01) (Summary) PAR-14-284
7/3/2014NIDDK Cooperative Hematology Specialized Core Centers (U54) (Summary) RFA-DK-14-001
View More Funding Opportunities

 

 Research Resources

 
Resource NameDescription
Diabetic Complications Consortium
The goal of the NIDDK-sponsored Diabetic Complications Consortium (DiaComp) is to foster communication and collaboration between investigator communities involved in complications research.  Toward this goal, DiaComp: (1) sponsors annual meetings in…
(Summary)
NIDDK Information Network

The NIDDK Information Network (dkNET), serves the needs of basic and clinical investigators by providing seamless access to large pools of data relevant to the mission of NIDDK. The goal of dkNET is to develop a community-based network for…

(Summary)
NIDDK Repository for Biosamples and Data

Supports Data, Biosample, and Genetic Repositories to increase the impact of current and previously funded NIDDK studies by making their data and biospecimens available to the broader scientific community. These Repositories enable scientists not…

(Summary)
Organ Procurement and Transplantation Network

The U.S. Organ Procurement and Transplantation Network (OPTN) maintains a registry of human tissues in order to ensure the success and efficiency of the U.S. organ transplant system.

(Summary)
NIH Common Fund

The intent of NIH Common Fund is to provide a strategic and nimble approach to address key roadblocks in biomedical research that impede basic scientific discovery and its translation into improved human health. In addition, these programs capitalize…

(Summary)

View Additional Research Resources

 

 NIDDK Active Trials in Hematologic Disease

 
View related clinical trials from ClinicalTrials.gov.

 

 Related Study Sections

 
Study sections conduct initial peer review of applications in a designated scientific area. View related study sections from the NIH's Center for Scientific Review.​​
 

 HEME-NETworks

 

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