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Gastrointestinal Microbiology and Infectious Diseases

The Gastrointestinal Microbiology and Infectious Diseases program supports basic, clinical, and translational research on the gut microbiota, pathogenic organisms that reside in the gastrointestinal tract, and the host-microbial interactions that affect host physiology and the pathophysiology of digestive diseases and nutrition.  In particular, the program focuses on research characterizing the structure and function of the intestinal microbiome; mechanisms by which organisms of the microbiome contribute to disease processes in the gastrointestinal tract; the interaction between diet and the microbiome as it relates to nutrient metabolism and energy intake; the host response to gastrointestinal infections, such as Helicobacter pylori, Clostridium difficile, pathogenic Escherichia coli, Vibrio cholera, and enteric viruses; and the interactions between the mucosal immune system and the intestinal microbiome to maintain normal homeostasis or imbalance leading to inflammation and disease pathophysiology.
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 NIDDK Staff

 
Frank Hamilton, M.D., M.P.H.Gastrointestinal and Nutrition AIDS; Gastrointestinal Endoscopy Research; Gastrointestinal Mucosa and Immunology; Gastrointestinal MotilityRobert W. Karp, Ph.D.Genetics, Genomics, and Microbiome Studies of the GI Tract, Liver, and Pancreatic Diseases, Nutrition, and Obesity
Padma Maruvada, Ph.D.Nutrient Metabolism; Clinical Obesity and NutritionPeter Perrin Ph.D.Gastrointestinal Host-Microbial Interactions, Basic Mucosal Immunology and Inflammation

 

 Related Funding Opportunities

 
Posted DateTitleFull Announcement
11/14/2014Administrative Supplements for Research on Sex/Gender Differences (Admin Supp) (Summary) PA-15-034
10/31/2014Research on Eosinophil Associated Disorders (R01) (Summary) PA-15-027
10/31/2014Research on Eosinophil Associated Disorders (R21) (Summary) PA-15-028
10/9/2014Studies of HIV in Digestive Diseases Limited to Gastrointestinal Mucosal Immunology and Liver Diseases (Summary) RFA-DK-14-019
7/30/2014NIDDK Central Repositories Non-renewable Sample Access (X01) (Summary) PAR-14-301
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The resources listed below include reagents, data, protocols, etc. If you would like to utilize any of these resources, contact the person associated with the resource.

 

 Research Resources

 
Resource NameDescription
Diabetic Complications Consortium
The goal of the NIDDK-sponsored Diabetic Complications Consortium (DiaComp) is to foster communication and collaboration between investigator communities involved in complications research.  Toward this goal, DiaComp: (1) sponsors annual meetings in…
Predicting Response to Standardized Pediatric Colitis Therapy

The mission of the PROTECT Study is to provide a better understanding of how children newly diagnosed with ulcerative colitis (UC) respond to mesalamine and prednisone (corticosteroid), the standard initial therapies used to treat this disorder…

Intestinal Stem Cell Consortium

The mission of the ISCC is to advance the understanding of intestinal epithelial stem cell biology during development, homeostasis, regeneration and disease. The immediate goals of the ISCC are to isolate, characterize, culture and validate…

Hyperglycemia and Pregnancy Outcomes Follow-Up Study Consortium

The goal of this follow-up study of mothers who participated in the Hyperglycemia and Adverse Pregnancy Outcomes (HAPO) study, is to determine the levels of blood sugar during pregnancy that are linked to increased body fat in the child, and to a…

NIDDK Information Network

The NIDDK Information Network (dkNET), serves the needs of basic and clinical investigators by providing seamless access to large pools of data relevant to the mission of NIDDK. The goal of dkNET is to develop a community-based network for…

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 NIDDK Active Trials in Digestive Disease

 
View related clinical trials from ClinicalTrials.gov.

 

 Related Study Sections

 
​​Study sections conduct initial peer review of applications in a designated scientific area. View related study sections from the NIH's Center for Scientific Review.