U.S. Department of Health and Human Services
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Gastrointestinal Physiology, Development, and Epithelial Biology

The Gastrointestinal (GI) Physiology, Development, and Epithelial Biology program supports basic and translational research on the development, structure, and function of the GI tract in health and disease.  This program focuses on GI development, regeneration, and healing, including the role of gastrointestinal stem cells and stem cell differentiation; basic biology of the GI epithelium, including studies on the structure and function of the epithelium, interactions between the epithelium and other components of the GI tract, and the integrity of the epithelium as a barrier; the cellular and molecular mechanisms regulating transport and absorption of water, ions, sugars, amino acids/peptides, lipids, vitamins, and minerals across the epithelium; requirements, bioavailability, and metabolism of nutrients and other dietary components at the organ, cellular, and subcellular levels in normal and diseased states; and normal and abnormal function of the enteric nervous system, including the structure and function of GI hormones and peptides.​​

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 NIDDK Staff

 
Jill L. Carrington, Ph.D.Basic Neurogastroenterology; Gastrointestinal Development, Epithelial Biology, and InflammationMichael J. Grey, Ph.D.Gastrointestinal Transport and Absorption; Gastrointestinal Host-Microbial Interactions; Basic Mucosal Immunology and Inflammation
Padma Maruvada, Ph.D.Nutrient Metabolism; Clinical Obesity and NutritionJose Serrano, M.D., Ph.D.Liver Bioengineering and Biotechnology; Cell and Molecular Biology of the Liver; Developmental Biology and Regeneration; Drug-induced Liver Disease; Gastrointestinal Neuroendocrinology; Exocrine Pancreas; Pancreatitis

 

 Related Funding Opportunities

 
Posted DateTitleFull Announcement
3/7/2014Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (Parent F31) (Summary) PA-14-147
3/7/2014Ruth L. Kirschstein National Research Service Award Individual Predoctoral Fellowship to Promote Diversity in Health-Related Research (Parent F31 - Diversity) (Summary) PA-14-148
3/7/2014Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (Parent F32) (Summary) PA-14-149
3/7/2014Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral MD/PhD or Other Dual-Doctoral Degree Fellowship (Parent F30) (Summary) PA-14-150
2/12/2014Empirical Research on Ethical Issues Related to Central IRBs and Consent for Research Using Clinical Records and Data (R01) (Summary) RFA-OD-14-002
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 Research Resources

 
Resource NameDescription
NIDDK Information Network

The NIDDK Information Network (dkNET), serves the needs of basic and clinical investigators by providing seamless access to large pools of data relevant to the mission of NIDDK. The goal of … (Summary)

Hyperglycemia and Pregnancy Outcomes Follow-Up Study Consortium

The goal of this follow-up study of mothers who participated in the Hyperglycemia and Adverse Pregnancy Outcomes (HAPO) study, is to determine the levels of blood sugar during pregnancy that … (Summary)

Diabetic Complications Consortium
The goal of the NIDDK-sponsored Diabetic Complications Consortium (DiaComp) is to foster communication and collaboration between investigator communities involved in complications research.  … (Summary)
Gastroparesis Clinical Research Consortium

The GpCRC is focusing on the etiology, natural history, and therapy of gastroparesis. The goal of this consortium is to perform clinical, epidemiological, and therapeutic research in gastroparesis … (Summary)

Intestinal Stem Cell Consortium

The mission of the ISCC is to advance the understanding of intestinal epithelial stem cell biology during development, homeostasis, regeneration and disease. The immediate goals of the ISCC … (Summary)

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 NIDDK Active Trials in Gastrointestinal Disease

 
View related clinical trials from ClinicalTrials.gov.

 

 Related Study Sections

 
​​Study sections conduct initial peer review of applications in a designated scientific area. View related study sections from the NIH's Center for Scientific Review.