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Hematopoiesis and Hematopoietic Stem Cell Biology

The Hematopoiesis and Hematopoietic Stem Cell Biology program focuses on understanding the basic cellular and molecular mechanisms underlying the production and function of blood cells in health and disease.  Major areas of interest include the basic mechanisms involved in regulating the production and terminal development of blood cells, referred to as hematopoiesis.  Specific areas of interest include: hematopoietic stem cell and progenitor cell phenotypes; regulation of gene expression during hematopoiesis; regulatory molecules and cytokines that influence stem cell and progenitor cell survival, proliferation, and maturation; mechanisms of hematopoietic cell cycle control and lineage commitment; comparative studies of hematopoiesis across species; ontogeny of hematopoietic tissue development; hematopoietic stem cell plasticity in mesenchymal tissue development; hematopoietic stem cells and progenitors as vehicles for gene therapy; and hematopoietic stem cell transplantation and the development of techniques for establishing stable hematopoietic chimeras in order to treat heritable blood diseases.​​​​​​​​​​​​​​

 

 NIDDK Staff

 
Terry Rogers Bishop, Ph.D.Hematology; Hematology Centers; Hematology Training

 

 Related Funding Opportunities

 
Posted DateTitleFull Announcement
10/3/2014Innovative Research in HIV in Kidney, Urology and Hematology (R01) (Summary) RFA-DK-14-020
9/4/2014Advancing Interventions to Improve Medication Adherence (R01) (Summary) PA-14-334
7/30/2014NIDDK Central Repositories Non-renewable Sample Access (X01) (Summary) PAR-14-301
7/29/2014NIDDK Clinician Scientist Mentoring Award to Promote Workforce Diversity (K05) (Summary) RFA-DK-14-005
7/17/2014High Throughput Screening (HTS) to Discover Chemical Probes (R01) (Summary) PAR-14-284
View More Funding Opportunities

The resources listed below include reagents, data, protocols, etc. If you would like to utilize any of these resources, contact the person associated with the resource.

 

 Research Resources

 
Resource NameDescription
Diabetic Complications Consortium
The goal of the NIDDK-sponsored Diabetic Complications Consortium (DiaComp) is to foster communication and collaboration between investigator communities involved in complications research.  Toward this goal, DiaComp: (1) sponsors annual meetings in…
(Summary)
NIDDK Information Network

The NIDDK Information Network (dkNET), serves the needs of basic and clinical investigators by providing seamless access to large pools of data relevant to the mission of NIDDK. The goal of dkNET is to develop a community-based network for…

(Summary)
NIDDK Repository for Biosamples and Data

Supports Data, Biosample, and Genetic Repositories to increase the impact of current and previously funded NIDDK studies by making their data and biospecimens available to the broader scientific community. These Repositories enable scientists not…

(Summary)
Organ Procurement and Transplantation Network

The U.S. Organ Procurement and Transplantation Network (OPTN) maintains a registry of human tissues in order to ensure the success and efficiency of the U.S. organ transplant system.

(Summary)
NIH Common Fund

The intent of NIH Common Fund is to provide a strategic and nimble approach to address key roadblocks in biomedical research that impede basic scientific discovery and its translation into improved human health. In addition, these programs capitalize…

(Summary)

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 NIDDK Active Trials in Hematologic Disease

 
View related clinical trials from ClinicalTrials.gov.

 

 Related Study Sections

 
Study sections conduct initial peer review of applications in a designated scientific area. View related study sections​ from the NIH's Center for Scientific Review.