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Hereditary and Pediatric Disorders of the Pancreas

The Hereditary and Pediatric Disorders of the Pancreas program supports research on the genetic factors contributing to the etiology of pancreatic diseases and on childhood disorders of the pancreas.  Particular areas of interest include understanding genetic factors and their interactions with exogenous insults, with respect to pathogenesis, complications, and natural history of pancreatitis and other pancreatic disorders.  Studies involve genetic screenings that identify gene mutations in candidate genes or their regulatory elements that are associated with pancreatic structural or functional abnormalities.  Researchers are focused on the identification of biologic or molecular mechanisms of pancreatic injury associated with the identification of mutant alleles; the generation of novel animal models of pancreatitis or abnormal pancreatic function by expression of mutant genes associated with pancreatic disease; and the identification of other genetic and environmental factors that influence the development and course of pancreatitis in genetically susceptible individuals.​​​​​​​​​​​​​

 

 NIDDK Staff

 
Dana K. Andersen, M.D.Observational and Investigational Clinical Research; Biomedical Devices, Surgical Interventions, and Medications
Jose Serrano, M.D., Ph.D.Liver Bioengineering and Biotechnology; Cell and Molecular Biology of the Liver; Developmental Biology and Regeneration; Drug-induced Liver Disease; Gastrointestinal Neuroendocrinology; Exocrine Pancreas; Pancreatitis

 

 Related Funding Opportunities

 
Posted DateTitleFull Announcement
7/30/2014NIDDK Central Repositories Non-renewable Sample Access (X01) (Summary) PAR-14-301
7/29/2014NIDDK Clinician Scientist Mentoring Award to Promote Workforce Diversity (K05) (Summary) RFA-DK-14-005
7/17/2014High Throughput Screening (HTS) to Discover Chemical Probes (R01) (Summary) PAR-14-284
7/2/2014Innovative Therapies and Tools for Screenable Disorders in Newborns (R01) (Summary) PAR-14-270
7/2/2014NIAID SBIR - Technology Transfer Direct Phase II (SBIR-TT) (R44) (Summary) RFA-AI-14-049
View More Funding Opportunities

​The resources listed below include reagents, data, protocols, etc.  If you would like to utilize any of these resources, contact the person associated with the resource.
 

 Research Resources

 
Resource NameDescription
Diabetic Complications Consortium
The goal of the NIDDK-sponsored Diabetic Complications Consortium (DiaComp) is to foster communication and collaboration between investigator communities involved in complications research.  Toward this goal, DiaComp: (1) sponsors annual meetings in…
(Summary)
NIDDK Information Network

The NIDDK Information Network (dkNET), serves the needs of basic and clinical investigators by providing seamless access to large pools of data relevant to the mission of NIDDK. The goal of dkNET is to develop a community-based network for…

(Summary)
NIDDK Repository for Biosamples and Data

Supports Data, Biosample, and Genetic Repositories to increase the impact of current and previously funded NIDDK studies by making their data and biospecimens available to the broader scientific community. These Repositories enable scientists not…

(Summary)
Type 1 Diabetes TrialNet

Type 1 Diabetes TrialNet (TrialNet) is an international network of researchers who are exploring ways to prevent, delay and reverse the progression of type 1 diabetes.

(Summary)
Study of Nutrition in Acute Pancreatitis

SNAP is a randomized multi-center clinical trial designed to test whether duodenojejunal (DJ) feeding is more effective than nasogastric (NG) feeding in providing enteral nutrition to patients with severe acute pancreatitis. SNAP will enroll…

(Summary)

View Additional Research Resources

 

 NIDDK Active Trials in Pancreatic Disease

 
View related clinical trials from ClinicalTrials.gov.

 

 Related Study Sections

 

Study sections conduct initial peer review of applications in a designated scientific area. View related study sections from the NIH's Center for Scientific Review.​