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Kidney Genetics and Genomics

The Kidney Genetics and Genomics program advances research that uses genetics and genomics approaches to understand the normal and pathologic functions of the kidney.  Studies seek to elucidate the heritability or molecular genetic basis of single-gene or genetically complex familial diseases in humans.  This work includes studies that identify and characterize quantitative trait loci or modifier loci affecting single-gene traits in humans or animal models.  The program advances studies of mutagenesis and mutant screens and genotype-phenotype correlations.

The research portfolio also includes work to develop statistical techniques for mapping quantitative trait loci or genes contributing to complex traits, such as haplotype mapping.  Program-supported researchers may develop microarray and other high-throughput genomics and proteomics technologies and genomics tools for creation of transgenic or knockout animals.  Research includes genomic analysis and genome-anatomy projects.​​​​​​​​​​

 

 NIDDK Staff

 
Paul L. Kimmel, M.D.Clinical AKI; Kidney Translational Genetics; Kidney Centers; Kidney HIV/AIDS
Rebekah Rasooly, Ph.D.Genetics and Genomics; Basic PKD

 

 Related Funding Opportunities

 
Posted DateTitleFull Announcement
9/24/2014Psychosocial and Behavioral Aspects of Bariatric Surgery (R01) (Summary) RFA-DK-14-026
9/4/2014Advancing Interventions to Improve Medication Adherence (R01) (Summary) PA-14-334
9/2/2014(Re)Building a Kidney Coordinating Center (U01) (Summary) RFA-DK-14-009
9/2/2014(Re)Building a Kidney: Cells to Organ (UH2/UH3) (Summary) RFA-DK-14-010
8/27/2014Consortium on Beta-cell Death and Survival (HIRN-CBDS) (UC4) (Summary) RFA-DK-14-021
View More Funding Opportunities

​The resources listed below include reagents, data, protocols, etc.  If you would like to utilize any of these resources, contact the person associated with the resource.
 

 Research Resources

 
Resource NameDescription
Action to Control Cardiovascular Disease Risk in Diabetes Follow-up Study
ACCORDION (sponsored by NHLBI) is a prospective, observational follow-up study of at least 8000 participants who were treated and followed in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) Trial.  Treatment in ACCORD ended in 2009 and…
(Summary)
Action for Health in Diabetes
Look AHEAD is a 16-center, randomized clinical trial investigating the long-term health effects of an intensive lifestyle intervention designed to produce weight loss. Look AHEAD enrolled 5,145 overweight or obese participants with type 2 diabetes…
(Summary)
Diabetic Complications Consortium
The goal of the NIDDK-sponsored Diabetic Complications Consortium (DiaComp) is to foster communication and collaboration between investigator communities involved in complications research.  Toward this goal, DiaComp: (1) sponsors annual meetings in…
(Summary)
Type 1 Diabetes-Rapid Access to Intervention Development
Type 1 Diabetes-Rapid Access to Intervention Development (T1D-RAID): T1D-RAID is not accepting new applications at this time, but currently supports ongoing projects. The goal of T1D-RAID is to facilitate translation from the lab to the clinic of…
(Summary)
Hyperglycemia and Pregnancy Outcomes Follow-Up Study Consortium

The goal of this follow-up study of mothers who participated in the Hyperglycemia and Adverse Pregnancy Outcomes (HAPO) study, is to determine the levels of blood sugar during pregnancy that are linked to increased body fat in the child, and to a…

(Summary)

View Additional Research Resources

 

 NIDDK Active Trials in Kidney Disease

 
View related clinical trials from ClinicalTrials.gov.

 

 Related Study Sections

 
​​Study sections conduct initial peer review of applications in a designated scientific area. View related study sections from the NIH's Center for Scientific Review.