U.S. Department of Health and Human Services

Kidney Inflammation and Inflammatory Diseases

The Kidney Inflammation and Inflammatory Diseases program advances research on both normal and pathologic renal processes involving immune- or inflammatory-mediated mechanisms.  Specific projects examine the basic processes that induce kidney cell damage and propagate kidney inflammation.  The program encourages research on these processes in the setting of systemic diseases and primary renal disorders, including chronic allograft nephropathy.  Basic processes of interest include the regulation of renal cell-signaling pathways and cell-surface determinant expression.  Also of interest are studies of cellular matrix protein expression and the regulation of cytokine and growth factor expression in inflammatory renal disease. Researchers investigate the interaction of a number of immune cells—including T and B cell lymphocytes, neutrophils, and macrophages—with renal-specific cell subsets.​​​​​​​​​​​​​​


 NIDDK Staff

Kevin Abbott, M.D., M.P.H.Kidney and Urology Epidemiology; Transplant; DialysisMichael Flessner, M.D., Ph.D.Clinical CKD; Glomerular Disease; Clinical PKD; PKD Centers


 Related Funding Opportunities

Posted DateTitleFull Announcement
8/7/2015Research Supplements to Promote Re-Entry into Biomedical and Behavioral Research Careers (Admin Supp) (Summary) PA-15-321
7/24/2015Lymphatics in Health and Disease in the Digestive System, Kidney, and Urinary Tract (R01) (Summary) PAR-15-306
7/23/2015GenitoUrinary Development Molecular Anatomy Project (GUDMAP) - Atlas Projects (U01) (Summary) RFA-DK-15-014
7/23/2015GenitoUrinary Development Molecular Anatomy Project (GUDMAP) - Database/Website Project (U24) (Summary) RFA-DK-15-015
7/23/2015GenitoUrinary Development Molecular Anatomy Project (GUDMAP) - Human Tissue Core (U24) (Summary) RFA-DK-15-016
View More Funding Opportunities

The resources listed below include reagents, data, protocols, etc. If you would like to utilize any of these resources, contact the person associated with the resource.


 Research Resources

Resource NameDescription
Action to Control Cardiovascular Disease Risk in Diabetes Follow-up Study
ACCORDION (sponsored by NHLBI) is a prospective, observational follow-up study of at least 8000 participants who were treated and followed in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) Trial.  Treatment in ACCORD ended in 2009 and…
Diabetic Complications Consortium
The goal of the NIDDK-sponsored Diabetic Complications Consortium (DiaComp) is to foster communication and collaboration between investigator communities involved in complications research.  Toward this goal, DiaComp: (1) sponsors annual meetings in…
Rare Kidney Stone Consortium

The Consortium facilitates cooperative exchange of information and resources among investigators, clinicians, patients, and researchers in order to improve care and outcomes for patients with rare stone diseases.  The consortium promotes ready…

Randomized Intervention for Children with Vesicoureteral Reflux

The purpose of this study is to learn whether all children with vesicoureteral reflux (VUR) should be treated with antibiotics. The study will tell us if prophylactic antibiotic treatment prevents urinary tract infections and renal scarring in…

United States Renal Data System

The United States Renal Data System (USRDS) is a national data system that collects, analyzes, and distributes information about end-stage renal disease (ESRD) in the United States. The USRDS is funded directly by the National Institute of Diabetes…

View Additional Research Resources


 NIDDK Active Trials in Kidney Disease

View related clinical trials from ClinicalTrials.gov.


 Related Study Sections

​​Study sections conduct initial peer review of applications in a designated scientific area. View related study sections from the NIH's Center for Scientific Review.