U.S. Department of Health and Human Services

Translational and Basic Liver Disease Research

The Translational and Basic Liver Disease Research program supports a wide range of scientific proposals that cover broad topics, such as cellular and molecular biology of the liver; developmental biology and regeneration of the liver; bile and bilirubin physiology and pathogenesis of cholestasis; liver cell injury, repair, and fibrosis; inflammation of the liver; and liver bioengineering and imaging.  Furthermore, disease-specific proposals that improve the understanding of pathophysiological mechanisms and treatment of specific liver diseases or liver conditions are also supported by this research program.​​​​​​​​​​​​​​​​

 

 NIDDK Staff

 
Bonnie Burgess-BeusseBile, Bilirubin, and Cholestasis; Cell and Molecular Biology of the Liver; Cell Injury, Repair, Fibrosis, and Inflammation; Developmental Biology and RegenerationEdward Doo, M.D.Fatty Liver Disease; Genetic Liver Disease; HIV and Liver; Pediatric Liver Disease; Viral Hepatitis and Infectious DiseasesDavid Saslowsky, Ph.D.Career Development Programs (K awards)
Jose Serrano, M.D., Ph.D.Gastrointestinal Neuroendocrinology; Exocrine Pancreas; Pancreatitis Averell H. Sherker, M.D., FRCPCAutoimmune Liver Disease; Acute Liver Failure; Complications of Chronic Liver Disease; Gallbladder and Biliary Diseases; Liver Bioengineering and Biotechnology; Liver Cancer; Liver Transplantation

 

 Related Funding Opportunities

 
Posted DateTitleFull Announcement
1/8/2016NIH Pathway to Independence Award (Parent K99/R00) (Summary) PA-16-077
1/5/2016Administrative Supplements for Research on Sex/Gender Differences (Admin Supp) (Summary) PA-16-066
12/18/2015Small Grants for New Investigators to Promote Diversity in Health-Related Research (R21) (Summary) PAR-16-064
12/11/2015Natural History of Disorders Identifiable by Screening of Newborns (R01) (Summary) PAR-16-061
12/7/2015Clinical Sites for the IDeA States Pediatric Clinical Trials Network (UG1) (Summary) RFA-OD-16-001
View More Funding Opportunities

The resources listed below include reagents, data, protocols, etc. If you would like to utilize any of these resources, contact the person associated with the resource.

 

 Research Resources

 
Resource NameDescription
Evaluating Predictors and Interventions in Sphincter of Oddi Dysfunction

The EPISOD study is a prospective, double-blind, randomized, sham-controlled, multi-center clinical trial. The EPISOD study enrolls subjects who have received a prior cholecystectomy and are diagnosed with the clinical syndrome of Sphincter of Oddi…

Acute Liver Failure Study Group
The Acute Liver Failure Study Group is collecting biosamples and information on the natural history, causes and outcomes of Acute Liver Failure in the United States. In addition to the database, a clinical trial conducted to test whether the drug…
Action to Control Cardiovascular Disease Risk in Diabetes Follow-up Study
ACCORDION (sponsored by NHLBI) is a prospective, observational follow-up study of at least 8000 participants who were treated and followed in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) Trial.  Treatment in ACCORD ended in 2009 and…
Diabetic Complications Consortium
The goal of the NIDDK-sponsored Diabetic Complications Consortium (DiaComp) is to foster communication and collaboration between investigator communities involved in complications research.  Toward this goal, DiaComp: (1) sponsors annual meetings in…
NIDDK Information Network

The NIDDK Information Network (dkNET), serves the needs of basic and clinical investigators by providing seamless access to large pools of data relevant to the mission of NIDDK. The goal of dkNET is to develop a community-based network for…

View Additional Research Resources

 

 NIDDK Active Trials in Liver Disease

 
View related clinical trials from ClinicalTrials.gov.

 

 Related Study Sections

 
Study sections conduct initial peer review of applications in a designated scientific area. View related study sections from the NIH's Center for Scientific Review.

NIH Common Fund

Learn about current projects and view funding opportunities sponsored by the​ ​​NIH Common Fund.​