U.S. Department of Health and Human Services
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Liver Clinical Research and Epidemiology

The Liver Clinical Research and Epidemiology program supports patient-oriented clinical research in liver diseases.  Work in the program examines a wide range of experimental interventions or diagnostics with direct impact on liver disease diagnosis or pathology endpoints.

The program emphasizes research on common and rare liver diseases and supports large clinical research networks.  Current and past clinical research networks supported by this program have included:  NASH Clinical Research Network, Adult-to-Adult Living Donor Liver Transplantation Cohort Study, Adult Acute Liver Failure Study Group, Pediatric Acute Liver Failure, Drug-Induced Liver Injury Network, Childhood Liver Disease Research and Education Network, Hepatitis B Research Network, Hepatitis C Antiviral Long-term Treatment against Cirrhosis, and Peds C.​​​​​​​​​​​​​​​

 

 NIDDK Staff

 
Edward Doo, M.D.Fatty Liver Disease; Genetic Liver Disease; HIV and Liver; Cell Injury, Repair, Fibrosis, and Inflammation; Pediatric Liver Disease; Viral Hepatitis and Infectious DiseasesJose Serrano, M.D., Ph.D.Liver Bioengineering and Biotechnology; Cell and Molecular Biology of the Liver; Developmental Biology and Regeneration; Drug-induced Liver Disease; Gastrointestinal Neuroendocrinology; Exocrine Pancreas; Pancreatitis
Averell H. Sherker, M.D., FRCP(C)Autoimmune Liver Disease; Acute Liver Failure; Bile, Bilirubin and Cholestasis; Complications of Chronic Liver Disease; Gallbladder and Biliary Diseases; Liver Cancer; Liver TransplantationAynur Unalp-Arida M.D., Ph.D.Epidemiology, Clinical Trials, Digestive Diseases, and Nutrition

 

 Related Funding Opportunities

 
Posted DateTitleFull Announcement
10/9/2014Studies of HIV in Digestive Diseases Limited to Gastrointestinal Mucosal Immunology and Liver Diseases (Summary) RFA-DK-14-019
9/4/2014Advancing Interventions to Improve Medication Adherence (R01) (Summary) PA-14-334
8/26/2014Limited Competition for the Continuation of the Hepatitis B Research Network Clinical Centers (U01) (Summary) RFA-DK-14-506
8/26/2014Limited Competition for the Continuation of the Hepatitis B Research Network Immunology Center (U01) (Summary) RFA-DK-14-509
8/26/2014Limited Competition for the Continuation of the Hepatitis B Research Network Data Coordination Center (U01) (Summary) RFA-DK-14-510
View More Funding Opportunities

The resources listed below include reagents, data, protocols, etc. If you would like to utilize any of these resources, contact the person associated with the resource.

 

 Research Resources

 
Resource NameDescription
Evaluating Predictors and Interventions in Sphincter of Oddi Dysfunction

The EPISOD study is a prospective, double-blind, randomized, sham-controlled, multi-center clinical trial. The EPISOD study enrolls subjects who have received a prior cholecystectomy and are diagnosed with the clinical syndrome of Sphincter of Oddi…

(Summary)
Acute Liver Failure Study Group
The Acute Liver Failure Study Group is collecting biosamples and information on the natural history, causes and outcomes of Acute Liver Failure in the United States. In addition to the database, a clinical trial conducted to test whether the drug…
(Summary)
Action to Control Cardiovascular Disease Risk in Diabetes Follow-up Study
ACCORDION (sponsored by NHLBI) is a prospective, observational follow-up study of at least 8000 participants who were treated and followed in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) Trial.  Treatment in ACCORD ended in 2009 and…
(Summary)
Diabetic Complications Consortium
The goal of the NIDDK-sponsored Diabetic Complications Consortium (DiaComp) is to foster communication and collaboration between investigator communities involved in complications research.  Toward this goal, DiaComp: (1) sponsors annual meetings in…
(Summary)
NIDDK Information Network

The NIDDK Information Network (dkNET), serves the needs of basic and clinical investigators by providing seamless access to large pools of data relevant to the mission of NIDDK. The goal of dkNET is to develop a community-based network for…

(Summary)

View Additional Research Resources

 

 NIDDK Active Trials in Liver Disease

 
​View related clinical trials from ClinicalTrials.gov.

 

 Related Study Sections

 
​​Study sections conduct initial peer review of applications in a designated scientific area. View related study sections from the NIH's Center for Scientific Review.