U.S. Department of Health and Human Services

Liver Clinical Research and Epidemiology

The Liver Clinical Research and Epidemiology program supports patient-oriented clinical research in liver diseases.  Work in the program examines a wide range of experimental interventions or diagnostics with direct impact on liver disease diagnosis or pathology endpoints.

The program emphasizes research on common and rare liver diseases and supports large clinical research networks.  Current and past clinical research networks supported by this program have included:  NASH Clinical Research Network, Adult-to-Adult Living Donor Liver Transplantation Cohort Study, Adult Acute Liver Failure Study Group, Pediatric Acute Liver Failure, Drug-Induced Liver Injury Network, Childhood Liver Disease Research and Education Network, Hepatitis B Research Network, Hepatitis C Antiviral Long-term Treatment against Cirrhosis, and Peds C.​​​​​​​​​​​​​​​

 

 NIDDK Staff

 
Edward Doo, M.D.Fatty Liver Disease; Genetic Liver Disease; HIV and Liver; Pediatric Liver Disease; Viral Hepatitis and Infectious DiseasesJose Serrano, M.D., Ph.D.Gastrointestinal Neuroendocrinology; Exocrine Pancreas; Pancreatitis
Averell H. Sherker, M.D., FRCPCAutoimmune Liver Disease; Acute Liver Failure; Complications of Chronic Liver Disease; Gallbladder and Biliary Diseases; Liver Bioengineering and Biotechnology; Liver Cancer; Liver TransplantationAynur Unalp-Arida M.D., M.Sc., Ph.D.Epidemiology, Clinical Trials, Digestive Diseases, and Nutrition

 

 Related Funding Opportunities

 
Posted DateTitleFull Announcement
1/8/2016NIH Pathway to Independence Award (Parent K99/R00) (Summary) PA-16-077
1/5/2016Administrative Supplements for Research on Sex/Gender Differences (Admin Supp) (Summary) PA-16-066
12/18/2015Small Grants for New Investigators to Promote Diversity in Health-Related Research (R21) (Summary) PAR-16-064
12/11/2015Natural History of Disorders Identifiable by Screening of Newborns (R01) (Summary) PAR-16-061
12/7/2015Clinical Sites for the IDeA States Pediatric Clinical Trials Network (UG1) (Summary) RFA-OD-16-001
View More Funding Opportunities

The resources listed below include reagents, data, protocols, etc. If you would like to utilize any of these resources, contact the person associated with the resource.

 

 Research Resources

 
Resource NameDescription
Evaluating Predictors and Interventions in Sphincter of Oddi Dysfunction

The EPISOD study is a prospective, double-blind, randomized, sham-controlled, multi-center clinical trial. The EPISOD study enrolls subjects who have received a prior cholecystectomy and are diagnosed with the clinical syndrome of Sphincter of Oddi…

Acute Liver Failure Study Group
The Acute Liver Failure Study Group is collecting biosamples and information on the natural history, causes and outcomes of Acute Liver Failure in the United States. In addition to the database, a clinical trial conducted to test whether the drug…
Action to Control Cardiovascular Disease Risk in Diabetes Follow-up Study
ACCORDION (sponsored by NHLBI) is a prospective, observational follow-up study of at least 8000 participants who were treated and followed in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) Trial.  Treatment in ACCORD ended in 2009 and…
Diabetic Complications Consortium
The goal of the NIDDK-sponsored Diabetic Complications Consortium (DiaComp) is to foster communication and collaboration between investigator communities involved in complications research.  Toward this goal, DiaComp: (1) sponsors annual meetings in…
NIDDK Information Network

The NIDDK Information Network (dkNET), serves the needs of basic and clinical investigators by providing seamless access to large pools of data relevant to the mission of NIDDK. The goal of dkNET is to develop a community-based network for…

View Additional Research Resources

 

 NIDDK Active Trials in Liver Disease

 
​View related clinical trials from ClinicalTrials.gov.

 

 Related Study Sections

 
​​Study sections conduct initial peer review of applications in a designated scientific area. View related study sections from the NIH's Center for Scientific Review.
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NIH Common Fund

Learn about current projects and view funding opportunities sponsored by the​ ​​NIH Common Fund.​