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Motility and Functional Gastrointestinal Disorders

The Motility and Functional Gastrointestinal Disorders program supports basic, clinical, and translational research on aspects of gut physiology regulating motility, including research on the structure of gastrointestinal muscles and the biochemistry of contractile processes and mechano-chemical energy conversion relations between metabolism and contractility in smooth muscle; the basic biology of gut smooth muscle and the role of the nervous system in digestion and factors that affect gut motility; and the effect of gastrointestinal diseases and disorders on gastrointestinal motility.  The program also supports clinical trials to test new treatments for functional gastrointestinal disorders and epidemiology studies to address risk factors for disease occurrence, prognosis, or natural history.  Particular clinical areas of interest include irritable bowel syndrome, gastroparesis, functional dyspepsia, colonic diverticular disease, swallowing disorders, and gastroesophageal reflux.

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 NIDDK Staff

 
Jill L. Carrington, Ph.D.Basic Neurogastroenterology; Gastrointestinal Development, Epithelial Biology, Stem Cell Biology, and Inflammation
Frank Hamilton, M.D., M.P.H.Gastrointestinal and Nutrition AIDS; Gastrointestinal Endoscopy Research; Gastrointestinal Mucosa and Immunology; Gastrointestinal Motility

 

 Related Funding Opportunities

 
Posted DateTitleFull Announcement
7/17/2014High Throughput Screening (HTS) to Discover Chemical Probes (R01) (Summary) PAR-14-284
7/2/2014Innovative Therapies and Tools for Screenable Disorders in Newborns (R01) (Summary) PAR-14-270
6/25/2014NIDDK Mentored Research Scientist Development Award (K01) (Summary) PAR-14-266
6/4/2014Research on Chronic Overlapping Pain Conditions (R01) (Summary) PA-14-244
5/20/2014Silvio O. Conte Digestive Diseases Research Core Centers (P30) (Summary) RFA-DK-14-012
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​The resources listed below include reagents, data, protocols, etc.  If you would like to utilize any of these resources, contact the person associated with the resource.
 

 Research Resources

 
Resource NameDescription
Hyperglycemia and Pregnancy Outcomes Follow-Up Study Consortium

The goal of this follow-up study of mothers who participated in the Hyperglycemia and Adverse Pregnancy Outcomes (HAPO) study, is to determine the levels of blood sugar during pregnancy that … (Summary)

NIDDK Information Network

The NIDDK Information Network (dkNET), serves the needs of basic and clinical investigators by providing seamless access to large pools of data relevant to the mission of NIDDK. The goal of … (Summary)

Diabetic Complications Consortium
The goal of the NIDDK-sponsored Diabetic Complications Consortium (DiaComp) is to foster communication and collaboration between investigator communities involved in complications research.  … (Summary)
Gastroparesis Clinical Research Consortium

The GpCRC is focusing on the etiology, natural history, and therapy of gastroparesis. The goal of this consortium is to perform clinical, epidemiological, and therapeutic research in gastroparesis … (Summary)

Intestinal Stem Cell Consortium

The mission of the ISCC is to advance the understanding of intestinal epithelial stem cell biology during development, homeostasis, regeneration and disease. The immediate goals of the ISCC … (Summary)

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 NIDDK Active Trials in Gastrointestinal Disease

 
View related clinical trials from ClinicalTrials.gov.

 

 Related Study Sections

 
Study sections conduct initial peer review of applications in a designated scientific area. View related study sections from the NIH's Center for Scientific Review.