Ancillary Studies to Large Studies to Understand the Heterogeneity in Older Adults with Diabetes
September 2020 Council
Point(s) of Contact
Christine Lee, M.D., M.S.
One third of adults age 65 and greater have diabetes, and health care utilization and cost is highest for this population. There is significant heterogeneity in biologic, clinical, functional and socioeconomic factors affecting the clinical course and management of diabetes for older adults. Given this complexity, both the older adult population with diabetes and their providers struggle to anticipate risk for poor outcomes and how best to manage the disease for each individual. This initiative seeks to encourage the ancillary studies to add important biologic, clinical, functional and/or socioeconomic factors to existing large databases, cohort studies or clinical trials to facilitate the study of heterogeneity in older adults with diabetes. The goal of such research is to understand which adults with diabetes are at highest risk for poor outcomes and uncover potential reasons for these poor outcomes. This knowledge will inform on the design of future clinical trials to study targeted interventions for subgroups most at risk for poor outcomes and ultimately lead to more specific guidelines for individualized care of older adults with diabetes.