Kidney Precision Medicine Project

May 2020 Council

Lead Division/Office

KUH

Point(s) of Contact

Cindy N. Roy, Ph.D.; Paul L. Kimmel, M.D., M.A.C.P.; Chris Ketchum, Ph.D.; Afshin Parsa, M.D., M.P.H.; Danny Gossett, Ph.D.; Deborah Hoshizaki, Ph.D.; Tracy Rankin, Ph.D., M.P.H.

Executive Summary

The objectives of the Kidney Precision Medicine Project (KPMP) are to ethically and safely obtain and evaluate human kidney biopsies from participants with Chronic Kidney Diseases (CKDs) or Acute Kidney Injuries (AKIs), create a kidney tissue atlas that incorporates healthy kidney reference tissue, define disease subgroups, and identify critical cells, pathways and targets for novel therapies. The NIDDK proposes to extend and expand support of the KPMP to capture the necessary power, biological variation, and disease heterogeneity to fully meet these objectives.