Stimulating Hematology Investigation: New Endeavors (SHINE) Topic: Bioinformatic Exploration of Hematology Cohort Data

September 2019 Council

Lead Division/Office

KUH

Point(s) of Contact

Cindy N. Roy, Ph.D.

Executive Summary

The SHINE program was started in FY2010 as a pool of revolving funds to support emerging fields in hematology research. To ensure that the program meets its goal of supporting emerging fields in hematology research, we plan to hold a workshop and consider a new topic, “Tools for Mining Cohort Data”. NIDDK proposes a workshop aimed to develop new partnerships between data science investigators and investigators curating clinical cohorts. The purpose of this workshop is to discuss state of the art tools for identification of disease pathways, especially in non-malignant hematologic diseases, and to identify the limitations inherent in existing tools. We expect the development of new tools for genotype-phenotype analyses and disease pathway prediction will provide unique insights into a range of inherited and acquired underlying diseases including the hemoglobinopathies, porphyrias, hereditary hemochromatosis and bone marrow failure disorders.