Understanding and Reducing Cardiovascular Disease in Type 1 Diabetes Mellitus

January 2020 Council

Lead Division/Office

DEM

Point(s) of Contact

Teresa Jones, M.D.

Executive Summary

The goal of this initiative is to promote research that enhances the understanding of the pathophysiology and epidemiology of cardiovascular disease (CVD) among individuals with type 1 diabetes (T1D), and the development of interventions to reduce CVD risk among these individuals. The overall goal is to develop evidence-based CVD guidelines to prevent or reduce CVD complications of T1D across the lifespan. We anticipate this initiative will support mechanistic trials to enhance understanding of the pathophysiology of CVD in T1D, as well as phase 2 trials with subclinical endpoints to inform the future development of larger trials focused on preventing or reducing the CVD complications of T1D.