U.S. Department of Health and Human Services

 Staff Contact

Dr. Krystyna Rys-Sikora, Project Leader for the National Kidney Research Dialogue

Kidney Research National Dialogue (KRND)

Idney Research National Dialogue LogoThe Kidney Research National Dialogue (KRND) seeks to identify important research questions or objectives, which if answered, would improve our understanding of kidney function, and aid in the prevention, treatment, and even reversal of kidney disease. KRND originated from a desire to gather input from anyone with a stake in kidney research, and to facilitate community-wide strategic planning discussions. The Dialogue consists of three phases:

PHASE I: (Completed)

KRND launched an open access interactive website for participants to post critical questions or objectives, and comment on other’s posts and prioritize submissions.  Authors categorized their ideas into specific topic areas: Acute Kidney Injury (AKI); Normal Biology, Development, and Physiology, Chronic Kidney Disease (CKD); Diabetic Nephropathy, End Stage Renal Disease (ESRD); Glomerulosclerosis/Inflammation; Hypertension; Translation; Polycystic Kidney Disease (PKD) and Training.

More than 1600 participants from 30+ countries posted over 300 ideas and 500 comments covering all areas of kidney research.  To view all postings and comments from Phase I, please see theKRND archived posts and comments.pdfKRND archived posts and comments (PDF, 1563 KB). 

PHASE II: (Completed)

KRND invited recognized experts to participate in one of 12 Phase II topic-specific working groups. Each group was charged with fully assessing the KRND postings from Phase I, identify research gaps, and develop a potential strategy for moving the field forward. Their recommendations were incorporated in the following commentaries published in the Clinical Journal of American Society of Nephrology. 

  1. Kidney Research National Dialogue Overview and Commentary
  2. Diabetic Nephropathy: A National Dialogue
  3. AKI: A Path Forward
  4. Defining Kidney Biology to Understand Renal Disease
  5. Dialysis Therapies: A National Dialogue
  6. Improving CKD Therapies and Care: A National Dialogue
  7. Propagating the Nephrology Research Workforce: A Kidney Research National Dialogue Training Commentary
  8. Pediatric Kidney Disease: Tracking Onset and Improving Clinical Outcomes
  9. Glomerular Disease: Looking Beyond Pathology
  10. Filling the holes in Cystic Kidney Disease Research
  11. The Last Mile: Translational Research to Improve CKD Outcomes
  12. The Kidney Research National Dialogue: Gearing Up to Move Forward


PHASE III: (Ongoing) 

All stakeholders are invited to continue the Dialogue by commenting on these commentaries through PubMed Commons.

We hope that the KRND constitutes a cohesive, integrated vision of future research opportunities to be pursued by the kidney research community and supported by the NIDDK through workshops and initiatives. NIDDK thanks all contributors to the KRND for your efforts.

*The KRND was developed and implemented by staff from the Division of Kidney, Urologic, and Hematologic Diseases​ and directed by Dr. Krystyna Rys-Sikora.​​​​​​​​

 KRND Updates

Word Cloud of KRND Discussions