Publications

A selection of recent and significant publications can be viewed below.

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TSH/IGF1 receptor crosstalk: Mechanism and clinical implications.: Krieger CC, Neumann S, Gershengorn MC.; Pharmacol Ther (2020 May) 209:107502. Abstract/Full Text
Arrestin-β-1 Physically Scaffolds TSH and IGF1 Receptors to Enable Crosstalk.: Krieger CC, Boutin A, Jang D, Morgan SJ, Banga JP, Kahaly GJ, Klubo-Gwiezdzinska J, Neumann S, Gershengorn MC.; Endocrinology (2019 Jun 1) 160:1468-1479. Abstract/Full Text
Discovery of a Positive Allosteric Modulator of the Thyrotropin Receptor: Potentiation of Thyrotropin-Mediated Preosteoblast Differentiation In Vitro.: Neumann S, Eliseeva E, Boutin A, Barnaeva E, Ferrer M, Southall N, Kim D, Hu X, Morgan SJ, Marugan JJ, Gershengorn MC.; J Pharmacol Exp Ther (2018 Jan) 364:38-45. Abstract/Full Text
Evidence That Graves' Ophthalmopathy Immunoglobulins Do Not Directly Activate IGF-1 Receptors.: Marcus-Samuels B, Krieger CC, Boutin A, Kahaly GJ, Neumann S, Gershengorn MC.; Thyroid (2018 May) 28:650-655. Abstract/Full Text
Taltirelin alleviates fatigue-like behavior in mouse models of cancer-related fatigue.: Dougherty JP, Wolff BS, Cullen MJ, Saligan LN, Gershengorn MC.; Pharmacol Res (2017 Oct) 124:1-8. Abstract/Full Text

Additional Publications

Thyrotropin, but Not Thyroid-Stimulating Antibodies, Induces Biphasic Regulation of Gene Expression in Human Thyrocytes.: Jang D, Morgan SJ, Klubo-Gwiezdzinska J, Banga JP, Neumann S, Gershengorn MC.; Thyroid (2020 Feb) 30:270-276. Abstract/Full Text
Thyrotropin Causes Dose-dependent Biphasic Regulation of cAMP Production Mediated by G(s) and G(i/o) Proteins.: Neumann S, Malik SS, Marcus-Samuels B, Eliseeva E, Jang D, Klubo-Gwiezdzinska J, Krieger CC, Gershengorn MC.; Mol Pharmacol (2020 Jan) 97:2-8. Abstract/Full Text
Normal Human Thyrocytes in Culture.: Morgan SJ, Neumann S, Gershengorn MC.; Methods Mol Biol (2018) 1817:1-7. Abstract/Full Text
Rebuttal to Smith and Janssen (Thyroid 2017;27:746-747. DOI: 10.1089/thy.2017.0281).: Neumann S, Gershengorn MC.; Thyroid (2017 Nov) 27:1459-1460. Abstract/Full Text
TSH/IGF-1 Receptor Cross-Talk Rapidly Activates Extracellular Signal-Regulated Kinases in Multiple Cell Types.: Krieger CC, Perry JD, Morgan SJ, Kahaly GJ, Gershengorn MC.; Endocrinology (2017 Oct 1) 158:3676-3683. Abstract/Full Text
TSHR/IGF-1R Cross-Talk, Not IGF-1R Stimulating Antibodies, Mediates Graves' Ophthalmopathy Pathogenesis.: Krieger CC, Neumann S, Marcus-Samuels B, Gershengorn MC.; Thyroid (2017 May) 27:746-747. Abstract/Full Text
Inhibiting thyrotropin/insulin-like growth factor 1 receptor crosstalk to treat Graves' ophthalmopathy: studies in orbital fibroblasts in vitro.: Place RF, Krieger CC, Neumann S, Gershengorn MC.; Br J Pharmacol (2017 Feb) 174:328-340. Abstract/Full Text
Thyrotropin and Insulin-Like Growth Factor 1 Receptor Crosstalk Upregulates Sodium-Iodide Symporter Expression in Primary Cultures of Human Thyrocytes.: Morgan SJ, Neumann S, Marcus-Samuels B, Gershengorn MC.; Thyroid (2016 Dec) 26:1794-1803. Abstract/Full Text
TSH/IGF-1 Receptor Cross Talk in Graves' Ophthalmopathy Pathogenesis.: Krieger CC, Place RF, Bevilacqua C, Marcus-Samuels B, Abel BS, Skarulis MC, Kahaly GJ, Neumann S, Gershengorn MC.; J Clin Endocrinol Metab (2016 Jun) 101:2340-7. Abstract/Full Text
The Treadmill Fatigue Test: A Simple, High-throughput Assay of Fatigue-like Behavior for the Mouse.: Dougherty JP, Springer DA, Gershengorn MC.; J Vis Exp (2016 May 31) Abstract/Full Text