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Christine Lee, M.D., M.S.

Clinical studies on the development, diagnosis and medical treatment of type 2 diabetes in adults; clinical studies of diabetes in older adults

Responsibilities & Activities

My portfolio includes both clinical observational studies and clinical trials to study (1) the development, diagnosis and medical treatment of type 2 diabetes in adults and (2) the etiology, natural history, diagnosis, and medical treatment of diabetes in older adults (over 65 years). I am also the project scientist for the Diabetes Prevention Program Outcomes Study (DPPOS), an over 15 year follow-up study of a diverse cohort of adults with pre-diabetes randomly assigned to lifestyle intervention or metformin, compared to placebo to understand the long-term effects of these interventions on diabetes, cardiovascular disease, cancer, microvascular outcomes, and age-related outcomes.

Research Programs

Clinical Research in Type 2 Diabetes
Studies in humans aimed at the prevention, treatment, and diagnosis of Type 2 Diabetes and the mechanistic aspects of its etiology.

Diabetes: Treatment, Prevention, & Complications
Basic and clinical studies aimed at addressing the prevention, treatment, and pathophysiology of type 1 and type 2 diabetes.

Pathophysiology of Diabetes & Metabolic Disease
Basic and clinical research that addresses the pathophysiology of metabolic diseases, including type 1 and type 2 diabetes.

Committees & Working Groups

  • NIH Geroscience Interest Group, Member
  • NIDDK Clinical Studies Working Group, Member
  • DEM Clinical Working Group, Member
  • NIDDK Obesity Research Working Group, Member