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Karen L. Teff, Ph.D.

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Effects of bariatric surgery on diabetes and metabolism, clinical and basic science of hepatic metabolism and hypoglycemia, human sleep and diabetes

Responsibilities & Activities

My portfolio includes basic and clinical research grants in the following areas: (1) the effects of bariatric surgery on diabetes and other outcomes associated with the pathophysiology of diabetes; (2) studies examining the mechanisms involved with, as well as the prevention, treatment, and pathophysiology of hypoglycemia; 3) autonomic control and contribution to metabolic dysfunction and 4) human sleep and circadian rhythms.

Research Programs

Clinical Research in Type 1 Diabetes
Determinants, etiology, progression, prevention, and treatment of type 1 diabetes in children and adults.

Clinical Research in Type 2 Diabetes
Progression and treatment of type 2 diabetes in children and adults.

Diabetes: Treatment, Prevention, & Complications

Metabolic Pathways
Studies on the pathways that are involved in intermediary metabolism as they impact endocrine and metabolic diseases.

Metabolism, Energy Balance & Obesity
Basic studies in non-human animals related to the neural control of energy balance and weight gain, loss and maintenance.

Pathophysiology of Diabetes & Metabolic Disease
Basic and clinical research that addresses the pathophysiology of metabolic diseases, including type 1 and type 2 diabetes.

Committees & Working Groups

  • Management Committee, DEM
  • Co-Director Office of Obesity Research
  • Clinical Sciences Working Group, Member
  • Trans-NIH SRCC, NIDDK representative
  • Stakeholder Engagement Working Group