U.S. Department of Health and Human Services
Averell Sherker

 Contact Info

Tel: 301-451-6207
Email: sherkerah@mail.nih.gov

 Select Experience

  • DirectorCenter for Liver Diseases, Associate Professor of Clinical Medicine, Washington Hospital Center, Georgetown University2001-2010
  • DirectorLiver Research, Associate Professor, SMBD-Jewish General Hospital, McGill University, Canada1993-2001
  • Postdoctoral Fellow Stanford University1989-1993
  • Residency/FellowshipUniversity of Toronto Teaching Hospitals, Canada1982-1989
  • M.D.Queen’s University, Canada1982

Averell H. Sherker, M.D., FRCPC

Program Director, Division of Digestive Diseases and Nutrition

Current Responsibilities & Activities

I serve as scientific advisor on research activities relating to viral hepatitis and liver diseases. As such, I provide scientific guidance to the DDN as it focuses and accelerates research on liver disease at the NIDDK. My work also helps the Division coordinate and stimulate liver-related research across the National Institutes of Health and within other federal agencies.  I provide advice to the Division as it supports research to develop practical, safe, and effective means to prevent, treat, and control the five forms of viral hepatitis. I also provide scientific guidance on basic and clinical liver research as well as the epidemiology of liver disease. My portfolio includes networks studying acute liver failure in adults and children, childhood liver disease, living-donor liver transplantation, hepatitis B, fatty liver disease, pediatric liver transplantation, drug-induced liver injury, and porphyria. I also oversee a portfolio of grants in autoimmune liver disease, liver transplantation, liver cancer, and cholestasis and biliary disease. Liver disease is an important cause of illness and death in the United States. Medical research on liver disease is critically important to reduce the impact of liver disease on human health.​

​Research Programs

Genetic Metabolic Disease
This program supports basic and clinical research that addresses the pathophysiology and treatment of inborn errors of metabolism and rare genetic metabolic diseases, including lipodystrophy, maturity onset diabetes of the young (MODY), Primary Hyperoxaluria, systemic amyloidosis and porphyria.

Liver Clinical Research and Epidemiology
The Liver Clinical Research and Epidemiology program supports patient-oriented clinical research and epidemiological research in liver diseases

Translational and Basic Liver Disease Research
This program supports both translational and basic research on liver physiology and pathophysiology and liver diseases

Current Committee Memberships

  • Trans-NIH Working Group for Extramural Undiagnosed Disease Program Steering CommitteeMember
  • Trans-NIH Primary Mitochondrial Disease Working GroupMember
  • Trans-NIH Committee on Viral HepatitisMember