U.S. Department of Health and Human Services
Guillermo Arreaza-Rubin

 Contact Info

Tel: 301-594-4724
Email: arreazag@mail.nih.gov

 Select Experience

  • Scientific DirectorDiabetogen Biosciences, Inc., London, Ontario, Canada2000-2005
  • Senior Research AssociateThe Robarts Research Institute, Autoimmunity/ Diabetes Group, University of Western Ontario1998-2000
  • Postdoctoral FellowshipThe Robarts Research Institute, Autoimmunity/Diabetes Group, University of Western Ontario1994-1997
  • Research FellowshipEndocrinology Research Laboratory, The Wellesley Hospital, Department of Medicine, University of Toronto1991-1994
  • Residency, Internal Medicine/EndocrinologyUniversity Hospital, Central University of Venezuela1985-1991

Guillermo A. Arreaza-Rubín, M.D.

Program Director, Division of Diabetes, Endocrinology, and Metabolic Diseases

Current Responsibilities & Activities

As director for clinical immunology of diabetes program and the technologies for the diagnosis and diabetes control program, I oversee a variety of research projects designed to improve diagnosis, treatment and monitoring of this disease.  My responsibilities include directing the Small Business Innovation Research/Small Business Technology Transfer Research (SBIR/STTR) program—which supports innovative research by small businesses that have the potential for commercialization—in areas related to immunology, diabetes and other endocrine and metabolic diseases.  These areas include:  drug discovery for diabetes and other endocrine diseases; new technologies for islet isolation, stem cell/regeneration, and transplantation; immune modulatory agents for the primary and secondary prevention of diabetes; inflammatory aspects of type 2 diabetes, insulin resistance, and obesity; and glucose control technologies.  I oversee academic research on closed-loop systems/artificial pancreas development including novel glucose sensors and integrated pancreatic hormone replacement delivery technologies.  My duties also include being program director for the Clinical Islet Transplantation (CIT) Consortium and the Clinical Islet Transplant Registry (CITR) acting as the executive secretary of the Clinical Islet Transplantation Consortium Data and Safety Monitoring Board.  I also participate in the coordination of the new human islet research network (HIRN) program as a program director for the consortium for modeling autoimmunity (CMAI) and I represent the NIDDK on several trans-NIH and interagency working groups on metabolic monitoring, inflammatory processes, autoimmunity and medical devices development and performance surveillance.

​Research Programs

Bioengineering, Biotechnology, and Imaging as applied to Diabetes, Metabolic, and Endocrine Diseases
This program supports research that is aimed at applying sophisticated, cutting-edge technologies to advance the understanding of the mechanisms that underlie diabetes and other endocrine and metabolic diseases

Endocrine Pancreas
The Endocrine Pancreas program supports research on the basic biology, development, and function of the endocrine pancreas as well as clinical studies on islet transplantation for the treatment of type 1 diabetes

Current Committee Memberships

  • Trans-NIH/FDA Medical Devices Research Interest GroupMember-NIDDK Representative
  • NIH/FDA Interagency Artificial Pancreas Working GroupNIDDK Representative
  • NIH-Immunology Interest GroupMember
  • Mycrophysiological systems trans NIH-working groupMember- NIDDK representative
  • Type 1 Diabetes Working GroupMember
  • Autoimmunity Working GroupMember
  • DEM and trans DK-Clinical Working GroupMember
  • Human Islet Research Working Groupmember
  • Steering Committee for the Glucose Monitoring Surveillance Programmember