U.S. Department of Health and Human Services
Alan Schechter

 Contact Info

Tel: 301-496-5408
Email: aschecht@helix.nih.gov

 Select Experience

  • Special Research FellowNIAMS, NIH1967-1969
  • Research AssociateNIAMS, NIH1965-1967
  • ResidentAlbert Einstein Medical College1963-1965
  • M.D.Columbia University1963
  • B.A.Cornell University1959

 Related Links

  • Molecular Biology/Biochemistry
  • Molecular Pharmacology/Toxicology
Research Summary/In Plain Language

Research in Plain Language

Our lab focuses on how nitric oxide (NO), an important cellular signaling molecule involved in many normal and disease-related processes, interacts with hemoglobin, a protein in the blood that carries oxygen from the lungs to the rest of the body.  We want to understand how NO may be transported by blood and possibly be used as a pharmacological agent to help deliver treatment.  Using NO in this way may contribute to development of therapies for a variety of diseases, such as sickle cell anemia, in which oxygen transport or other aspects of blood flow are impaired.  We are also studying the role of NO as a signaling messenger within or between cells and how the nitrite/NO pathway affects blood clotting.