Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted.
The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit
Updates regarding government operating status and resumption of normal operations can be found at

U.S. Department of Health and Human Services
Arthur Sherman

 Contact Info

Tel: 301-496-4325

 Select Experience

  • Ph.D.New York University1986
  • M.S.New York University1983
  • B.A.Cornell University1973

 Related Links

  • Cell Biology/Cell Signaling
  • Computational Biology/Bioinformatics/Biostatistics/Mathematics
  • Neuroscience/Neurophysiology/Neurodevelopment
Research Summary/In Plain Language

Research in Plain Language

Insulin is a hormone that allows the body to use carbohydrates for quick energy.  This spares fat for long-term energy storage and protein for building muscle and regulating cellular processes.  Without sufficient insulin many tissues, such as muscle, cannot use glucose, the product of digestion of carbohydrates, as a fuel.  This leads to diabetes, a rise in blood sugar that damages organs. It also leads to heart disease, kidney failure, blindness, and finally, premature death.  We use mathematics to study how the beta cells of the pancreas know how much glucose is available and how much insulin to secrete.