U.S. Department of Health and Human Services
Astrid Haase

 Contact Info

Tel: 301-451-5125
Email: astrid.haase@nih.gov

 Select Experience

  • Post Doctoral FellowCold Spring Harbor Laboratory2007-2015
  • Graduate StudentFriedrich Miescher Insitute for Biomedical Research2002-2007
  • Ph.D.University of Basel, Switzerland2007
  • M.D.University of Vienna, Austria2002

 Related Links


Astrid D. Haase, M.D., Ph.D.

Acting Section Chief, RNA Biology SectionLaboratory of Cell and Molecular Biology
  • Chromosome Biology/Epigenetics
  • Developmental Biology
  • Molecular Biology/Biochemistry
Research Summary/In Plain Language

Research in Plain Language

Genomes are massive databases that tell the body how to create cells, tissues, and organs. It is important to protect these databases and make sure that the genes within them keep their integrity.  This is essential for fertility in animals and the survival of each species. Additionally, loss of genomic integrity has been observed in many diseases including cancer.

To protect these databases, the body uses various kinds of molecular guards. Our group studies a particular class of molecular guards that protect germ cells. Little is known about their elaborate surveillance system and defense strategies. We aim to generate valuable knowledge of how these databases are maintained.