U.S. Department of Health and Human Services
Carson Chow

 Contact Info

Tel: 301-402-8250
Email: carsonc@niddk.nih.gov

 Select Experience

  • Ph.D.Massachusetts Institute of Technology1992

 Related Links


Carson C. Chow, Ph.D.

Section Chief, Mathematical Biology SectionLaboratory of Biological Modeling
  • Computational Biology/Bioinformatics/Biostatistics/Mathematics


A selection of recent and significant publications can be viewed below.

Vandevijvere S, Chow CC, Hall KD, Umali E, Swinburn BA. Increased food energy supply as a major driver of the obesity epidemic: a global analysis. Bull World Health Organ. 2015 Jul 1; 93 (2015 Jul 1; 93; 7):446-56. [Full Text/Abstract]
Chow CC, Finn KK, Storchan GB, Lu X, Sheng X, Simons SS Jr. Kinetically-defined component actions in gene repression. PLoS Comput Biol. 2015 Mar; 11 (3; 11; 2015 Mar):e1004122. [Full Text/Abstract]
Stavreva DA, Coulon A, Baek S, Sung MH, John S, Stixova L, Tesikova M, Hakim O, Miranda T, Hawkins M, Stamatoyannopoulos JA, Chow CC, Hager GL. Dynamics of chromatin accessibility and long-range interactions in response to glucocorticoid pulsing. Genome Res. 2015 Feb 12; 25 (25; 6; 2015 Feb 12):845-57. [Full Text/Abstract]
Chang CC, Chow CC, Tellier LC, Vattikuti S, Purcell SM, Lee JJ. Second-generation PLINK: rising to the challenge of larger and richer datasets. Gigascience. 2015 Feb 25; 4 (2015 Feb 25; 4):7. [Full Text/Abstract]
Chow CC, Buice MA. Path integral methods for stochastic differential equations. J Math Neurosci. 2015 Mar 24; 5 (2015 Mar 24; 5):8. [Full Text/Abstract]
Chow CC, Ong KM, Kagan B, Simons SS Jr. Theory of partial agonist activity of steroid hormones. AIMS Mol Sci. 2015; 2 (2015; 2):101-123. [Full Text/Abstract]
Coulon A, Ferguson ML, de Turris V, Palangat M, Chow CC, Larson DR. Kinetic competition during the transcription cycle results in stochastic RNA processing. Elife. 2014 Oct 1; 3 (2014 Oct 1; 3). [Full Text/Abstract]
Lee JJ, Chow CC. Conditions for the validity of SNP-based heritability estimation. Hum Genet. 2014 Aug; 133 (133; 8; 2014 Aug):1011-22. [Full Text/Abstract]
Chow CC, Hall KD. Short and long-term energy intake patterns and their implications for human body weight regulation. Physiol Behav. 2014 Jul; 134 (134; 2014 Jul):60-5. [Full Text/Abstract]
Blackford JA Jr, Brimacombe KR, Dougherty EJ, Pradhan M, Shen M, Li Z, Auld DS, Chow CC, Austin CP, Simons SS Jr. Research Resource: Modulators of glucocorticoid receptor activity identified by a new high-throughput screening assay. Mol Endocrinol. 2014 Jul; 28 (28; 7; 2014 Jul):me20141069. [Full Text/Abstract]
Kong AP, Yang X, Luk A, Cheung KK, Ma RC, So WY, Ho CS, Chan MH, Ozaki R, Chow CC, Brown N, Chan JC. Hypoglycaemia, chronic kidney disease and death in type 2 diabetes: the Hong Kong diabetes registry. BMC Endocr Disord. 2014 Jun 13; 14 (14; 2014 Jun 13):48. [Full Text/Abstract]
Chan JC, Sui Y, Oldenburg B, Zhang Y, Chung HH, Goggins W, Au S, Brown N, Ozaki R, Wong RY, Ko GT, Fisher E, JADE and PEARL Project Team. Effects of telephone-based peer support in patients with type 2 diabetes mellitus receiving integrated care: a randomized clinical trial. JAMA Intern Med. 2014 Jun; 174 (6; 174; 2014 Jun):972-81. [Full Text/Abstract]
Vattikuti S, Lee JJ, Chang CC, Hsu SD, Chow CC. Applying compressed sensing to genome-wide association studies. Gigascience. 2014 Jun 16; 3 (2014 Jun 16; 3):10. [Full Text/Abstract]
Hall KD, Chow CC. Why is the 3500 kcal per pound weight loss rule wrong?. Int J Obes (Lond). 2013 Dec; 37 (2013 Dec; 37; 12):1614. [Full Text/Abstract]
Hall KD, Butte NF, Swinburn BA, Chow CC. Dynamics of childhood growth and obesity: development and validation of a quantitative mathematical model. Lancet Diabetes Endocrinol. 2013 Oct; 1 (2013 Oct; 2; 1):97-105. [Full Text/Abstract]
Lee JJ, Chow CC. The causal meaning of Fisher's average effect. Genet Res (Camb). 2013 Jun; 95 (95; 2-3; 2013 Jun):89-109. [Full Text/Abstract]
Buice MA, Chow CC. Beyond mean field theory: statistical field theory for neural networks. J Stat Mech. 2013 Mar; 2013 (2013 Mar; 2013):P03003. [Full Text/Abstract]
Buice MA, Chow CC. Dynamic finite size effects in spiking neural networks. PLoS Comput Biol. 2013; 9 (9; 1; 2013):e1002872. [Full Text/Abstract]
Buice MA, Chow CC. Generalized activity equations for spiking neural network dynamics. Front Comput Neurosci. 2013 Nov 15; 7 (2013 Nov 15; 7):162. [Full Text/Abstract]
Heuett WJ, Miller BV 3rd, Racette SB, Holloszy JO, Chow CC, Periwal V. Bayesian functional integral method for inferring continuous data from discrete measurements. Biophys J. 2012 Feb 8; 102 (102; 2012 Feb 8; 3):399-406. [Full Text/Abstract]
Simons SS Jr, Chow CC. The road less traveled: new views of steroid receptor action from the path of dose-response curves. Mol Cell Endocrinol. 2012 Jan 30; 348 (348; 2; 2012 Jan 30):373-82. [Full Text/Abstract]
Dougherty EJ, Guo C, Simons SS Jr, Chow CC. Deducing the temporal order of cofactor function in ligand-regulated gene transcription: theory and experimental verification. PLoS One. 2012; 7 (2012; 7; 1):e30225. [Full Text/Abstract]
Vattikuti S, Guo J, Chow CC. Heritability and genetic correlations explained by common SNPs for metabolic syndrome traits. PLoS Genet. 2012; 8 (2012; 8; 3):e1002637. [Full Text/Abstract]
Gotts SJ, Chow CC, Martin A. Repetition priming and repetition suppression: Multiple mechanisms in need of testing. Cogn Neurosci. 2012; 3 (3-4; 2012; 3):250-9. [Full Text/Abstract]
Gotts SJ, Chow CC, Martin A. Repetition Priming and Repetition Suppression: A Case for Enhanced Efficiency Through Neural Synchronization. Cogn Neurosci. 2012; 3 (3-4; 2012; 3):227-237. [Full Text/Abstract]
Buice MA, Chow CC. Effective stochastic behavior in dynamical systems with incomplete information. Phys Rev E Stat Nonlin Soft Matter Phys. 2011 Nov; 84 (2011 Nov; 5 Pt 1; 84):051120. [Full Text/Abstract]
Seely J, Chow CC. Role of mutual inhibition in binocular rivalry. J Neurophysiol. 2011 Nov; 106 (106; 2011 Nov; 5):2136-50. [Full Text/Abstract]
Hall KD, Sacks G, Chandramohan D, Chow CC, Wang YC, Gortmaker SL, Swinburn BA. Quantification of the effect of energy imbalance on bodyweight. Lancet. 2011 Aug 27; 378 (378; 2011 Aug 27; 9793):826-37. [Full Text/Abstract]
Chow CC, Periwal V, Csako G, Ricks M, Courville AB, Miller BV 3rd, Vega GL, Sumner AE. Higher acute insulin response to glucose may determine greater free fatty acid clearance in African-American women. J Clin Endocrinol Metab. 2011 Aug; 96 (8; 2011 Aug; 96):2456-63. [Full Text/Abstract]
Hall KD, Chow CC. Estimating changes in free-living energy intake and its confidence interval. Am J Clin Nutr. 2011 Jul; 94 (94; 2011 Jul; 1):66-74. [Full Text/Abstract]
Fatakia SN, Costanzi S, Chow CC. Molecular evolution of the transmembrane domains of G protein-coupled receptors. PLoS One. 2011; 6 (2011; 6; 11):e27813. [Full Text/Abstract]
Ong KM, Blackford JA Jr, Kagan BL, Simons SS Jr, Chow CC. A theoretical framework for gene induction and experimental comparisons. Proc Natl Acad Sci U S A. 2010 Apr 13; 107 (107; 2010 Apr 13; 15):7107-12. [Full Text/Abstract]
Vattikuti S, Chow CC. A computational model for cerebral cortical dysfunction in autism spectrum disorders. Biol Psychiatry. 2010 Apr 1; 67 (2010 Apr 1; 7; 67):672-8. [Full Text/Abstract]
Hall KD, Guo J, Dore M, Chow CC. The progressive increase of food waste in America and its environmental impact. PLoS One. 2009 Nov 25; 4 (2009 Nov 25; 4; 11):e7940. [Full Text/Abstract]
Furchtgott LA, Chow CC, Periwal V. A model of liver regeneration. Biophys J. 2009 May 20; 96 (2009 May 20; 10; 96):3926-35. [Full Text/Abstract]
Periwal V, Chow CC, Bergman RN, Ricks M, Vega GL, Sumner AE. Evaluation of quantitative models of the effect of insulin on lipolysis and glucose disposal. Am J Physiol Regul Integr Comp Physiol. 2008 Oct; 295 (2008 Oct; 4; 295):R1089-96. [Full Text/Abstract]
Chow CC, Hall KD. The dynamics of human body weight change. PLoS Comput Biol. 2008 Mar 28; 4 (2008 Mar 28; 4; 3):e1000045. [Full Text/Abstract]
Buice MA, Chow CC. Correlations, fluctuations, and stability of a finite-size network of coupled oscillators. Phys Rev E Stat Nonlin Soft Matter Phys. 2007 Sep; 76 (76; 3 Pt 1; 2007 Sep):031118. [Full Text/Abstract]
Hildebrand EJ, Buice MA, Chow CC. Kinetic theory of coupled oscillators. Phys Rev Lett. 2007 Feb 2; 98 (2007 Feb 2; 98; 5):054101. [Full Text/Abstract]
Periwal V, Chow CC. Patterns in food intake correlate with body mass index. Am J Physiol Endocrinol Metab. 2006 Nov; 291 (291; 5; 2006 Nov):E929-36. [Full Text/Abstract]
Moldakarimov S, Rollenhagen JE, Olson CR, Chow CC. Competitive dynamics in cortical responses to visual stimuli. J Neurophysiol. 2005 Nov; 94 (94; 2005 Nov; 5):3388-96. [Full Text/Abstract]
Chow CC, Clermont G, Kumar R, Lagoa C, Tawadrous Z, Gallo D, Betten B, Bartels J, Constantine G, Fink MP, Billiar TR, Vodovotz Y. The acute inflammatory response in diverse shock states. Shock. 2005 Jul; 24 (2005 Jul; 24; 1):74-84. [Full Text/Abstract]
Rubin JE, Gerkin RC, Bi GQ, Chow CC. Calcium time course as a signal for spike-timing-dependent plasticity. J Neurophysiol. 2005 May; 93 (93; 2005 May; 5):2600-13. [Full Text/Abstract]
Kumar R, Clermont G, Vodovotz Y, Chow CC. The dynamics of acute inflammation. J Theor Biol. 2004 Sep 21; 230 (230; 2004 Sep 21; 2):145-55. [Full Text/Abstract]
Alvarez VA, Chow CC, Van Bockstaele EJ, Williams JT. Frequency-dependent synchrony in locus ceruleus: role of electrotonic coupling. Proc Natl Acad Sci U S A. 2002 Mar 19; 99 (6; 2002 Mar 19; 99):4032-6. [Full Text/Abstract]
Laing CR, Chow CC. A spiking neuron model for binocular rivalry. J Comput Neurosci. 2002 Jan-Feb; 12 (12; 1; 2002 Jan-Feb):39-53. [Full Text/Abstract]