Red blood cells are critical to our survival. They contain a metalloprotein called hemoglobin. Hemoglobin carries oxygen obtained in our lungs to other tissues. Hemoglobin releases the oxygen, and oxygen helps convert nutrients to energy. Nutrient conversion produces carbon dioxide. Hemoglobin binds to and returns carbon dioxide to the lungs. The lungs expel it from the body. Red blood cells are specialized cells. They develop from a blood stem cell. A factor called GATA-1 induces their development. GATA-1 controls gene transcription. Specifically, GATA-1 influences all the genes necessary for the production and function of red blood cells. My goal is to understand red blood cell development. I study GATA-1’s interactions with DNA and other proteins.