U.S. Department of Health and Human Services
 

 Contact Info

 
Tel: 301-496-5889
Email: ceceliat@mail.nih.gov
 

 Select Experience

 
  • IRTA FellowshipLMB, NIDDK, NIH1988-1991
  • FellowshipAbbot Laboratories1987
  • Ph.D.Northwestern University1988
  • M.S.George Washington University1980
 

 Related Links

 

    Cecelia Trainor, Ph.D.

    Staff Scientist, Physical Chemistry SectionLaboratory of Molecular Biology
    Specialties
    • Molecular Biology/Biochemistry
    Research Summary/In Plain Language

    Research Summary

    Research Goal

    The goal is to understand the mechanism through which GATA-1 controls erythropoiesis.  GATA-1 exerts its effects by binding to specific DNA sites to activate genes and to participate in long-range chromatin interactions.  It also participates in many protein-protein interactions. The downstream consequences of these are not yet completely understood. 

    Current Research

    My research is focused on the major erythroid transcription factor GATA-1 and the role it plays in DNA binding, regulating gene expression, and in controlling red blood cell development.​

    Applying our Research

    A number of human diseases are known to be associated with mutations in GATA-1 and in other members of the GATA transcription factor family.A better understanding of the mechanism of action for this family of proteins should improve prospects for intervention in these diseases.