U.S. Department of Health and Human Services
Clifton Bogardus III

 Contact Info

Tel: 602-200-5211
Email: clifton_bogardus@nih.gov

 Select Experience

  • ChiefPhoenix Epidemiology and Clinical Research Branch, NIDDK, NIH2000–present
  • ChiefClinical Diabetes and Nutrition Section, NIDDK, NIH1985–2000
  • NIH Clinical Research Training FellowshipUniversity of Vermont1979–1982
  • Internal Medicine ResidencyDartmouth - Hitchcock Medical Center1977–1979
  • CommanderU.S. Army Health Clinic1975–1977
  • Internal Medicine InternshipDartmouth - Hitchcock Medical Center1974–1975
  • M.D.University of Rochester School of Medicine1974
  • B.S.Lafayette College1970

 Related Links

  • Clinical Research
  • Endocrinology
  • Epidemiology/Population Sciences
  • Genetics/Genomics
  • Health Disparities
Research Summary/In Plain Language

Research Summary

Research Goal

The goal of our research is to determine the etiology of type 2 diabetes mellitus and obesity and their complications to improve prevention and treatment.​

Current Research

Our research goal is to determine the role of genetic and physiologic factors in the etiology of type 2 diabetes mellitus and obesity and their complications.  We use genome-wide association studies to identify variants associated with type 2 diabetes, obesity, and pre-diabetic/pre-obesity traits in specific populations.  We look at expression data from skeletal muscle and adipose biopsies to identify expression profiles and metabolic traits that may predict disease onset.  Identifying, quantifying, and understanding specific genetically determined susceptibility or protective factors could lead to prevention by identifying individuals at risk and to improved treatment.

Applying our Research

Identifying the specific etiologies of type 2 diabetes mellitus and obesity will lead to improved prevention and treatments.

Need for Further Study

The prevalence of obesity and type 2 diabetes mellitus is increasing throughout the developed and developing world and disproportionally affects minority populations. The causes of these conditions are complex and include genetic, environmental, and lifestyle factors that may vary between populations. To improve prevention and treatments, more research is needed to identify the specific factors increasing susceptibility to these conditions in different populations.