U.S. Department of Health and Human Services
 

 Contact Info

 
Tel: 301-594-8416
Email: cuilingl@mail.nih.gov
 

 Select Experience

 
  • Research AssociateContractor, Mammalian Genetics Section, GDDB, NIDDK, NIH2004-2006
  • BIO-TRAC training course: Transgenic Technology: Method and ApplicationFAES Graduate School at NIH2000
  • Research FellowGDDB, NIDDK, NIH1998-2004
  • Visiting FellowLaboratory of Biochemistry and Metabolism, NIDDK, NIH1996-1998
  • CertificateShanghai College of Traditional Chinese Medicine1993
  • Research AssistantSchool of Pharmacy, Medical University1992-1994
  • B.S.Shanghai Medical University, School of Pharmacy1992
 

 Related Links

 

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    Cuiling Li, Ph.D.

    Biologist, Office of the Chief, Genetics of Development and Disease Branch
    Biologist, Mouse Knockout Core
    Specialties
    • Cancer Biology
    • Cell Biology/Cell Signaling
    • Developmental Biology
    • Genetics/Genomics
    • Molecular Biology/Biochemistry
    • Stem Cells/Induced Pluripotent Stem Cells

    ​Publications

    A selection of recent and significant publications can be viewed below.

    Publications
    Jeong SM, Xiao C, Finley LW, Lahusen T, Souza AL, Pierce K, Li YH, Wang X, Laurent G, German NJ, Xu X, Li C, Wang RH, Lee J, Csibi A, Cerione R, Blenis J, Clish CB, Kimmelman A, Deng CX, Haigis MC. SIRT4 has tumor-suppressive activity and regulates the cellular metabolic response to DNA damage by inhibiting mitochondrial glutamine metabolism. Cancer Cell. 2013 Apr 15; 23 (23; 4; 2013 Apr 15):450-63. [Full Text/Abstract]
    Kim HS, Vassilopoulos A, Wang RH, Lahusen T, Xiao Z, Xu X, Li C, Veenstra TD, Li B, Yu H, Ji J, Wang XW, Park SH, Cha YI, Gius D, Deng CX. SIRT2 maintains genome integrity and suppresses tumorigenesis through regulating APC/C activity. Cancer Cell. 2011 Oct 18; 20 (20; 2011 Oct 18; 4):487-99. [Full Text/Abstract]
    Wang RH, Li C, Deng CX. Liver steatosis and increased ChREBP expression in mice carrying a liver specific SIRT1 null mutation under a normal feeding condition. Int J Biol Sci. 2010 Nov 16; 6 (6; 7; 2010 Nov 16):682-90. [Full Text/Abstract]
    Li C, Li YP, Fu XY, Deng CX. Anterior visceral endoderm SMAD4 signaling specifies anterior embryonic patterning and head induction in mice. Int J Biol Sci. 2010 Sep 27; 6 (6; 2010 Sep 27):569-83. [Full Text/Abstract]
    Kim SS, Cao L, Baek HJ, Lim SC, Li C, Wang RH, Xu X, Cho KH, Deng CX. Impaired skin and mammary gland development and increased gamma-irradiation-induced tumorigenesis in mice carrying a mutation of S1152-ATM phosphorylation site in Brca1. Cancer Res. 2009 Dec 15; 69 (69; 2009 Dec 15; 24):9291-300. [Full Text/Abstract]
    Wang RH, Sengupta K, Li C, Kim HS, Cao L, Xiao C, Kim S, Xu X, Zheng Y, Chilton B, Jia R, Zheng ZM, Appella E, Wang XW, Ried T, Deng CX. Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice. Cancer Cell. 2008 Oct 7; 14 (14; 4; 2008 Oct 7):312-23. [Full Text/Abstract]
    Kim BG, Li C, Qiao W, Mamura M, Kasprzak B, Anver M, Wolfraim L, Hong S, Mushinski E, Potter M, Kim SJ, Fu XY, Deng C, Letterio JJ. Smad4 signalling in T cells is required for suppression of gastrointestinal cancer. Nature. 2006 Jun 22; 441 (441; 7096; 2006 Jun 22):1015-9. [Full Text/Abstract]
    Wang RH, Li C, Xu X, Zheng Y, Xiao C, Zerfas P, Cooperman S, Eckhaus M, Rouault T, Mishra L, Deng CX. A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression. Cell Metab. 2005 Dec; 2 (6; 2; 2005 Dec):399-409. [Full Text/Abstract]
    Li C, Xu X, Nelson DK, Williams T, Kuehn MR, Deng CX. FGFR1 function at the earliest stages of mouse limb development plays an indispensable role in subsequent autopod morphogenesis. Development. 2005 Nov; 132 (2005 Nov; 21; 132):4755-64. [Full Text/Abstract]