U.S. Department of Health and Human Services
Griffin Rodgers

 Contact Info

Tel: 301-496-0001
Email: griffin.rodgers@nih.gov

 Select Experience

  • M.B.A.Johns Hopkins University2005
  • M.D.Brown University1979
  • M.M.Sc.Brown University1979
  • Sc.B.Brown University1976

 Related Links


 Director's Biography

View Dr. Rodgers' Director's Biography.​

Griffin P. Rodgers, M.D., M.A.C.P.

Director, Office of the Director​
Chief, Molecular and Clinical Hematology Branch
Section Chief, Molecular Hematology Section, Molecular and Clinical Hematology Branch

Specialties: Molecular Biology/Biochemistry, Chemistry/Chemical Biology, Genetics/Genomics, Hematology​​​

Griffin P. Rodgers, M.D., M.A.C.P

Chief, Molecular and Clinical Hematology Branch
Section Chief, Molecular Hematology SectionMolecular and Clinical Hematology Branch
Director, Office of the Director
  • Chemistry/Chemical Biology
  • Genetics/Genomics
  • Hematology
  • Molecular Biology/Biochemistry


A selection of recent and significant publications can be viewed below.

Charles BA, Hsieh MM, Adeyemo AA, Shriner D, Ramos E, Chin K, Srivastava K, Zakai NA, Cushman M, McClure LA, Howard V, Flegel WA, Rotimi CN, Rodgers GP. Analyses of genome wide association data, cytokines, and gene expression in African-Americans with benign ethnic neutropenia. PLoS One. 2018; 13 (2018; 13; 3):e0194400. [Full Text/Abstract]
Liu W, Rodgers GP. Olfactomedin 4 expression and functions in innate immunity, inflammation, and cancer. Cancer Metastasis Rev. 2016 May 13; 35 (35; 2; 2016 May 13):201-12. [Full Text/Abstract]
Liu W, Li H, Hong SH, Piszczek GP, Chen W, Rodgers GP. Olfactomedin 4 deletion induces colon adenocarcinoma in ApcMin/+ mice. Oncogene. 2016 Mar 14; 35 (2016 Mar 14; 40; 35):5237-5247. [Full Text/Abstract]
Aerbajinai W, Liu L, Zhu J, Kumkhaek C, Chin K, Rodgers GP. Glia Maturation Factor-γ Regulates Monocyte Migration through Modulation of β1-Integrin. J Biol Chem. 2016 Feb 19; 291 (291; 16; 2016 Feb 19):8549-8564. [Full Text/Abstract]
Li H, Liu W, Chen W, Zhu J, Deng CX, Rodgers GP. Olfactomedin 4 deficiency promotes prostate neoplastic progression and is associated with upregulation of the hedgehog-signaling pathway. Sci Rep. 2015 Nov 19; 5 (2015 Nov 19; 5):16974. [Full Text/Abstract]
Steinberg MH, Rodgers GP. HbA2 : biology, clinical relevance and a possible target for ameliorating sickle cell disease. Br J Haematol. 2015 Jun 24; 170 (170; 6; 2015 Jun 24):781-7. [Full Text/Abstract]
Zhu J, Chin K, Aerbajinai W, Kumkhaek C, Li H, Rodgers GP. Hydroxyurea-inducible SAR1 gene acts through the Giα/JNK/Jun pathway to regulate γ-globin expression. Blood. 2014 Aug 14; 124 (124; 2014 Aug 14; 7):1146-56. [Full Text/Abstract]
Hsieh MM, Fitzhugh CD, Weitzel RP, Link ME, Coles WA, Zhao X, Rodgers GP, Powell JD, Tisdale JF. Nonmyeloablative HLA-matched sibling allogeneic hematopoietic stem cell transplantation for severe sickle cell phenotype. JAMA. 2014 Jul 2; 312 (2014 Jul 2; 312; 1):48-56. [Full Text/Abstract]
Liu W, Yan M, Sugui JA, Li H, Xu C, Joo J, Kwon-Chung KJ, Coleman WG, Rodgers GP. Olfm4 deletion enhances defense against Staphylococcus aureus in chronic granulomatous disease. J Clin Invest. 2013 Sep 3; 123 (123; 2013 Sep 3; 9):3751-5. [Full Text/Abstract]
Kumkhaek C, Aerbajinai W, Liu W, Zhu J, Uchida N, Kurlander R, Hsieh MM, Tisdale JF, Rodgers GP. MASL1 induces erythroid differentiation in human erythropoietin-dependent CD34+ cells through the Raf/MEK/ERK pathway. Blood. 2013 Apr 18; 121 (121; 16; 2013 Apr 18):3216-27. [Full Text/Abstract]
Kumkhaek C, Liu W, Rodgers GP. Identification and characterization of novel full-length cDNAs expressed during hematopoietic lineage-specific differentiation of cultured human peripheral blood mononuclear cells. Blood Cells Mol Dis. 2013 Mar; 50 (2013 Mar; 50; 3):154-5. [Full Text/Abstract]
Liu L, Aerbajinai W, Ahmed SM, Rodgers GP, Angers S, Parent CA. Radil controls neutrophil adhesion and motility through β2-integrin activation. Mol Biol Cell. 2012 Dec; 23 (2012 Dec; 23; 24):4751-65. [Full Text/Abstract]
Liu W, Yan M, Liu Y, McLeish KR, Coleman WG Jr, Rodgers GP. Olfactomedin 4 inhibits cathepsin C-mediated protease activities, thereby modulating neutrophil killing of Staphylococcus aureus and Escherichia coli in mice. J Immunol. 2012 Sep 1; 189 (189; 5; 2012 Sep 1):2460-7. [Full Text/Abstract]
Aerbajinai W, Liu L, Chin K, Zhu J, Parent CA, Rodgers GP. Glia maturation factor-γ mediates neutrophil chemotaxis. J Leukoc Biol. 2011 Sep; 90 (2011 Sep; 3; 90):529-38. [Full Text/Abstract]
Chen L, Li H, Liu W, Zhu J, Zhao X, Wright E, Cao L, Ding I, Rodgers GP. Olfactomedin 4 suppresses prostate cancer cell growth and metastasis via negative interaction with cathepsin D and SDF-1. Carcinogenesis. 2011 Jul; 32 (32; 7; 2011 Jul):986-94. [Full Text/Abstract]
Zhu J, Chin K, Aerbajinai W, Trainor C, Gao P, Rodgers GP. Recombinant erythroid Kruppel-like factor fused to GATA1 up-regulates delta- and gamma-globin expression in erythroid cells. Blood. 2011 Mar 17; 117 (2011 Mar 17; 117; 11):3045-52. [Full Text/Abstract]
Liu W, Lee HW, Liu Y, Wang R, Rodgers GP. Olfactomedin 4 is a novel target gene of retinoic acids and 5-aza-2'-deoxycytidine involved in human myeloid leukemia cell growth, differentiation, and apoptosis. Blood. 2010 Dec 2; 116 (2010 Dec 2; 23; 116):4938-47. [Full Text/Abstract]
Liu W, Yan M, Liu Y, Wang R, Li C, Deng C, Singh A, Coleman WG Jr, Rodgers GP. Olfactomedin 4 down-regulates innate immunity against Helicobacter pylori infection. Proc Natl Acad Sci U S A. 2010 Jun 15; 107 (107; 2010 Jun 15; 24):11056-61. [Full Text/Abstract]
Hsieh MM, Tisdale JF, Rodgers GP, Young NS, Trimble EL, Little RF. Neutrophil count in African Americans: lowering the target cutoff to initiate or resume chemotherapy?. J Clin Oncol. 2010 Apr 1; 28 (2010 Apr 1; 28; 10):1633-7. [Full Text/Abstract]
Hsieh MM, Kang EM, Fitzhugh CD, Link MB, Bolan CD, Kurlander R, Childs RW, Rodgers GP, Powell JD, Tisdale JF. Allogeneic hematopoietic stem-cell transplantation for sickle cell disease. N Engl J Med. 2009 Dec 10; 361 (2009 Dec 10; 24; 361):2309-17. [Full Text/Abstract]
Aerbajinai W, Zhu J, Kumkhaek C, Chin K, Rodgers GP. SCF induces gamma-globin gene expression by regulating downstream transcription factor COUP-TFII. Blood. 2009 Jul 2; 114 (114; 2009 Jul 2; 1):187-94. [Full Text/Abstract]
Chin KL, Aerbajinai W, Zhu J, Drew L, Chen L, Liu W, Rodgers GP. The regulation of OLFM4 expression in myeloid precursor cells relies on NF-kappaB transcription factor. Br J Haematol. 2008 Nov; 143 (3; 2008 Nov; 143):421-32. [Full Text/Abstract]
Zoueva OP, Garrett LJ, Bodine D, Rodgers GP. BP1 motif in the human beta-globin promoter affects beta-globin expression during embryonic/fetal erythropoiesis in transgenic mice bearing the human beta-globin gene. Blood Cells Mol Dis. 2008 Nov-Dec; 41 (2008 Nov-Dec; 41; 3):244-51. [Full Text/Abstract]
Kumkhaek C, Taylor JG 6th, Zhu J, Hoppe C, Kato GJ, Rodgers GP. Fetal haemoglobin response to hydroxycarbamide treatment and sar1a promoter polymorphisms in sickle cell anaemia. Br J Haematol. 2008 Apr; 141 (2008 Apr; 2; 141):254-9. [Full Text/Abstract]
Liu W, Liu Y, Zhu J, Wright E, Ding I, Rodgers GP. Reduced hGC-1 protein expression is associated with malignant progression of colon carcinoma. Clin Cancer Res. 2008 Feb 15; 14 (2008 Feb 15; 14; 4):1041-9. [Full Text/Abstract]
Aerbajinai W, Zhu J, Gao Z, Chin K, Rodgers GP. Thalidomide induces gamma-globin gene expression through increased reactive oxygen species-mediated p38 MAPK signaling and histone H4 acetylation in adult erythropoiesis. Blood. 2007 Oct 15; 110 (8; 2007 Oct 15; 110):2864-71. [Full Text/Abstract]
Hsieh MM, Linde NS, Wynter A, Metzger M, Wong C, Langsetmo I, Lin A, Smith R, Rodgers GP, Donahue RE, Klaus SJ, Tisdale JF. HIF prolyl hydroxylase inhibition results in endogenous erythropoietin induction, erythrocytosis, and modest fetal hemoglobin expression in rhesus macaques. Blood. 2007 Sep 15; 110 (6; 110; 2007 Sep 15):2140-7. [Full Text/Abstract]
Liu W, Zhu J, Cao L, Rodgers GP. Expression of hGC-1 is correlated with differentiation of gastric carcinoma. Histopathology. 2007 Aug; 51 (2007 Aug; 2; 51):157-65. [Full Text/Abstract]
Chen L, Gao Z, Zhu J, Rodgers GP. Identification of CD13+CD36+ cells as a common progenitor for erythroid and myeloid lineages in human bone marrow. Exp Hematol. 2007 Jul; 35 (2007 Jul; 35; 7):1047-55. [Full Text/Abstract]
Hsieh MM, Everhart JE, Byrd-Holt DD, Tisdale JF, Rodgers GP. Prevalence of neutropenia in the U.S. population: age, sex, smoking status, and ethnic differences. Ann Intern Med. 2007 Apr 3; 146 (146; 7; 2007 Apr 3):486-92. [Full Text/Abstract]