U.S. Department of Health and Human Services
Herman Edskes

 Contact Info

Tel: 301-496-1309
Email: edskes@helix.nih.gov

 Select Experience

  • Research FellowNIH2000-2001
  • Postdoctoral FellowNIH1995-1999
  • Ph.D.University of Kentucky1994
  • M.Sc.Wageningen University1990

 Related Links

  • Genetics/Genomics
  • Microbiology/Infectious diseases (non-viral)
  • Molecular Biology/Biochemistry
  • Prions
  • Virology

​Research Images

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Ure2-GFP aggregates in a [URE3] prion cell.Ure2-GFP fluorescence in a strain containing [URE3] and in a strain lacking the prion ([ure-o])Ure2-GFP aggregates in a [URE3] prion cell.Enlarge
Model of two amyloid variants.The model depicts two variant structures of a yeast prion amyloid formed by in-register parallel beta sheets.  The amyloid filament direction is indicated by a big gray arrow.  Parallel interacting sheets of neighboring proteins are indicated by aligned black and white arrows.  The yellow oval and star represent two of the in-register amino acids.Model of two amyloid variants.Enlarge
Filaments of Ure2 protein in a [URE3] prion cell.Electron microscopy reveals filaments (red) of Ure2 protein in a [URE3] prion cell.Filaments of Ure2 protein in a [URE3] prion cell.Enlarge