U.S. Department of Health and Human Services
Jeffrey Kopp

 Contact Info

Tel: 301-594-3403
Email: jeffreyk@mail.nih.gov

 Select Experience

  • Consulting NephrologistMark Hatfield Clinical Research Center, NIHPresent
  • Commissioned Officer (Captain) Active Member (Rapid Deployment Force Teams PHS 1)U.S. Public Health ServicePresent
  • Adjunct Professor of MedicineUniformed Services University of the Health SciencesPresent
  • Senior InvestigatorNIDDK, NIH1995-present
  • Medical Staff FellowNIH1987-1995
  • Complete Training in Internal Medicine and NephrologyUniversity of Washington1987
  • M.D.University of Pennsylvania Medical School1980
  • B.A.Harvard College1975

 Related Links


Jeffrey B. Kopp, M.D.

Chief, Kidney Diseases Branch
Section Chief, Kidney Disease SectionKidney Diseases Branch
  • Clinical Research
  • Genetics/Genomics
  • Health Disparities

​Research Images

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PodocytesPodocytes surround the glomerular capillaries; their actin-rich foot processes inter-digitate with processes from other podocytes and attach to the glomerular basement membrane. The slit diaphragms between these foot processes prevent passage of large macromolecules from plasma into the urinary space.PodocytesEnlarge
C22 PeakWe set out to find susceptibility genes for focal segmental glomerulosclerosis (FSGS) and HIV-associated nephropathy, two diseases of the glomerular podocyte that are more common among African Americans. An admixture scan found an excess of African origin genetic segments in individuals with kidney disease compared to controls. The primary genetic variants that account for this admixture peak are coding variants in APOL1, encoding apolipoprotein L1.C22 PeakEnlarge