U.S. Department of Health and Human Services
Judah Lee Rosner

 Contact Info

Tel: 301-496-0201
Email: jlrosner@helix.nih.gov

 Select Experience

  • Ph.D.Yale University1967
  • M.A.Yale University1964
  • B.A.Columbia College1960

 Related Links


Judah L. Rosner, Ph.D.

Senior Investigator, Molecular Genetics SectionLaboratory of Molecular Biology
  • Genetics/Genomics
  • Microbiology/Infectious diseases (non-viral)
  • Molecular Biology/Biochemistry


A selection of recent and significant publications can be viewed below.

FĂ brega A, Martin RG, Rosner JL, Tavio MM, Vila J. Constitutive SoxS expression in a fluoroquinolone-resistant strain with a truncated SoxR protein and identification of a new member of the marA-soxS-rob regulon, mdtG. Antimicrob Agents Chemother. 2010 Mar; 54 (3; 2010 Mar; 54):1218-25. [Full Text/Abstract]
Rosner JL, Martin RG. An excretory function for the Escherichia coli outer membrane pore TolC: upregulation of marA and soxS transcription and Rob activity due to metabolites accumulated in tolC mutants. J Bacteriol. 2009 Aug; 191 (2009 Aug; 16; 191):5283-92. [Full Text/Abstract]
Zhang A, Rosner JL, Martin RG. Transcriptional activation by MarA, SoxS and Rob of two tolC promoters using one binding site: a complex promoter configuration for tolC in Escherichia coli. Mol Microbiol. 2008 Sep; 69 (69; 6; 2008 Sep):1450-5. [Full Text/Abstract]
Martin RG, Bartlett ES, Rosner JL, Wall ME. Activation of the Escherichia coli marA/soxS/rob regulon in response to transcriptional activator concentration. J Mol Biol. 2008 Jul 4; 380 (380; 2008 Jul 4; 2):278-84. [Full Text/Abstract]
Kawano M, Storz G, Rao BS, Rosner JL, Martin RG. Detection of low-level promoter activity within open reading frame sequences of Escherichia coli. Nucleic Acids Res. 2005; 33 (2005; 19; 33):6268-76. [Full Text/Abstract]
Thomason LC, Court DL, Datta AR, Khanna R, Rosner JL. Identification of the Escherichia coli K-12 ybhE gene as pgl, encoding 6-phosphogluconolactonase. J Bacteriol. 2004 Dec; 186 (186; 2004 Dec; 24):8248-53. [Full Text/Abstract]
Dangi B, Gronenborn AM, Rosner JL, Martin RG. Versatility of the carboxy-terminal domain of the alpha subunit of RNA polymerase in transcriptional activation: use of the DNA contact site as a protein contact site for MarA. Mol Microbiol. 2004 Oct; 54 (2004 Oct; 54; 1):45-59. [Full Text/Abstract]
Martin RG, Rosner JL. Transcriptional and translational regulation of the marRAB multiple antibiotic resistance operon in Escherichia coli. Mol Microbiol. 2004 Jul; 53 (2004 Jul; 53; 1):183-91. [Full Text/Abstract]
Martin RG, Rosner JL. Analysis of microarray data for the marA, soxS, and rob regulons of Escherichia coli. Methods Enzymol. 2003; 370 (2003; 370):278-80. [Full Text/Abstract]
Martin RG, Rosner JL. Genomics of the marA/soxS/rob regulon of Escherichia coli: identification of directly activated promoters by application of molecular genetics and informatics to microarray data. Mol Microbiol. 2002 Jun; 44 (6; 44; 2002 Jun):1611-24. [Full Text/Abstract]
Rosner JL, Dangi B, Gronenborn AM, Martin RG. Posttranscriptional activation of the transcriptional activator Rob by dipyridyl in Escherichia coli. J Bacteriol. 2002 Mar; 184 (2002 Mar; 184; 5):1407-16. [Full Text/Abstract]
Martin RG, Gillette WK, Martin NI, Rosner JL. Complex formation between activator and RNA polymerase as the basis for transcriptional activation by MarA and SoxS in Escherichia coli. Mol Microbiol. 2002 Jan; 43 (43; 2; 2002 Jan):355-70. [Full Text/Abstract]