U.S. Department of Health and Human Services
Kiyoshi Mizuuchi

 Contact Info

Tel: 301-496-8154
Email: kmizu@helix.nih.gov

 Select Experience

  • D.S. (Ph.D.)Osaka University1972
  • M.S.Osaka University1969
  • B.S.Osaka University1967

 Related Links


Kiyoshi Mizuuchi, Ph.D.

Section Chief, Genetic Mechanisms SectionLaboratory of Molecular Biology
  • Biomedical Engineering/Biophysics/Physics
  • Cancer Biology
  • Microbiology/Infectious diseases (non-viral)
  • Molecular Biology/Biochemistry
  • Systems Biology


A selection of recent and significant publications can be viewed below.

Vecchiarelli AG, Li M, Mizuuchi M, Mizuuchi K. Differential affinities of MinD and MinE to anionic phospholipid influence Min Patterning dynamics in vitro. Mol Microbiol. 2014 Aug; 93 (93; 2014 Aug; 3):453-63. [Full Text/Abstract]
Vecchiarelli AG, Neuman KC, Mizuuchi K. A propagating ATPase gradient drives transport of surface-confined cellular cargo. Proc Natl Acad Sci U S A. 2014 Apr 1; 111 (2014 Apr 1; 111; 13):4880-5. [Full Text/Abstract]
Hwang LC, Vecchiarelli AG, Han YW, Mizuuchi M, Harada Y, Funnell BE, Mizuuchi K. ParA-mediated plasmid partition driven by protein pattern self-organization. EMBO J. 2013 May 2; 32 (2013 May 2; 32; 9):1238-49. [Full Text/Abstract]
Vecchiarelli AG, Hwang LC, Mizuuchi K. Cell-free study of F plasmid partition provides evidence for cargo transport by a diffusion-ratchet mechanism. Proc Natl Acad Sci U S A. 2013 Apr 9; 110 (110; 15; 2013 Apr 9):E1390-7. [Full Text/Abstract]
Vecchiarelli AG, Han YW, Tan X, Mizuuchi M, Ghirlando R, Biertümpfel C, Funnell BE, Mizuuchi K. ATP control of dynamic P1 ParA-DNA interactions: a key role for the nucleoid in plasmid partition. Mol Microbiol. 2010 Oct; 78 (2010 Oct; 78; 1):78-91. [Full Text/Abstract]
Han YW, Mizuuchi K. Phage Mu transposition immunity: protein pattern formation along DNA by a diffusion-ratchet mechanism. Mol Cell. 2010 Jul 9; 39 (39; 2010 Jul 9; 1):48-58. [Full Text/Abstract]
Ivanov V, Mizuuchi K. Multiple modes of interconverting dynamic pattern formation by bacterial cell division proteins. Proc Natl Acad Sci U S A. 2010 May 4; 107 (107; 2010 May 4; 18):8071-8. [Full Text/Abstract]
Skoko D, Li M, Huang Y, Mizuuchi M, Cai M, Bradley CM, Pease PJ, Xiao B, Marko JF, Craigie R, Mizuuchi K. Barrier-to-autointegration factor (BAF) condenses DNA by looping. Proc Natl Acad Sci U S A. 2009 Sep 29; 106 (106; 39; 2009 Sep 29):16610-5. [Full Text/Abstract]
Greene EC, Mizuuchi K. Target immunity during Mu DNA transposition. Transpososome assembly and DNA looping enhance MuA-mediated disassembly of the MuB target complex. Mol Cell. 2002 Dec; 10 (6; 2002 Dec; 10):1367-78. [Full Text/Abstract]
Yanagihara K, Mizuuchi K. Mismatch-targeted transposition of Mu: a new strategy to map genetic polymorphism. Proc Natl Acad Sci U S A. 2002 Aug 20; 99 (17; 2002 Aug 20; 99):11317-21. [Full Text/Abstract]
Greene EC, Mizuuchi K. Direct observation of single MuB polymers: evidence for a DNA-dependent conformational change for generating an active target complex. Mol Cell. 2002 May; 9 (2002 May; 9; 5):1079-89. [Full Text/Abstract]