U.S. Department of Health and Human Services

 Contact Info

Tel: 301-594-3479
Email: ln112e@nih.gov

 Select Experience

  • Staff ScientistNIDDK, NIH2004–Present
  • Research Assistant ProfessorDepartment of Human Genetics, Mount Sinai School of Medicine1997–2004
  • Ph.D.State University of New York at Stony Brook1991

 Related Links

  • Cell Biology/Cell Signaling
  • Developmental Biology
  • Molecular Biology/Biochemistry
Research Summary/In Plain Language

Research in Plain Language

Our group investigates the functions of nuclear receptors. Nuclear receptors are a special type of protein that regulates gene expression to control how cells respond. When a molecule binds to a nuclear receptor, the protein changes and triggers a reaction within the cell. Such molecules are called ligands. Nuclear receptors bind to various types of ligands, some of which include differerent types of hormones. Thyroid hormone and steroid hormones are among them. Nuclear receptors mediate important functions in many tissues. Our group studies how these receptors regulate the development of the nervous system. Our research focuses on the development of hearing and vision.