U.S. Department of Health and Human Services
Oksana Gavrilova

 Contact Info

Tel: 301-435-5370
Email: oksanag@intra.niddk.nih.gov

 Select Experience

  • Staff Scientist and Core DirectorMouse Metabolism Core Laboratory, NIDDK, NIH2002–Present
  • Staff ScientistDiabetes, Endocrinology, and Obesity Branch, NIDDK, NIH2000–2002
  • Visiting Research FellowDiabetes, Endocrinology, and Obesity Branch, NIDDK, NIH1994–2000
  • Research FellowUniversity of Texas Southwestern Medical Center1993–1994
  • Research ScientistInstitute of Genetics and Selection of Industrial Microorganisms 1987–1993
  • Ph.D.Institute of Genetics and Selection of Industrial Microorganisms1989
  • M.S.Moscow State University1983

 Related Links


Oksana Gavrilova, Ph.D.

Director, Mouse Metabolism Core
  • Physiology and Metabolism
Research Summary/In Plain Language

Research Summary

Research Goal

Our goal is to understand how environmental and genetic causes affect metabolism.  

Current Research

The primary objective of the Mouse Metabolism Core is to support research in the area of obesity and diabetes by providing standardized, high-quality phenotyping services for mouse models of diabetes, obesity, and related disorders.  Our services include analysis of body composition and energy balance, euglycemic-hyperinsulinemic clamp, fatty acid oxidation in vivo and in isolated muscle, as well as isolation and transplantation of pancreatic islet.   We also perform measurements of major metabolites and hormones in mouse serum and provide hands-on training in methods commonly used for analyses of energy and glucose metabolism in rodents.​

Applying our Research

This research will help us understand the mechanisms underlying obesity and diabetes. It will also facilitate the development of treatments for these diseases.

Need for Further Study

In spite of the prevalence of obesity and diabetes in modern society, our understanding of their molecular basis is rudimentary. In particular, we need to learn more about the role of the central nervous system in the regulation of energy balance and glucose metabolism.