U.S. Department of Health and Human Services
Orna Cohen-Fix

 Contact Info

Tel: 301-594-2184
Email: ornacf@helix.nih.gov

 Select Experience

  • Adjunct ProfessorJohns Hopkins University2011–Present
  • Directorthe NIH/Johns Hopkins University Graduate Partnership Program, NIH2008–present
  • Senior Investigator and Section ChiefNIDDK, NIH2005–Present
  • Tenure-Track InvestigatorNIDDK, NIH1998–2005
  • Postdoctoral FellowThe Carnegie Institution of Washington1994–1998
  • Ph.D.Weizmann Institute of Science1994
  • M.S.Weizmann Institute of Science1989
  • B.A.Tel-Aviv University1986

 Related Links


    • Cell Biology/Cell Signaling


    A selection of recent and significant publications can be viewed below.

    Rahman MM, Rosu S, Joseph-Strauss D, Cohen-Fix O. Down-regulation of tricarboxylic acid (TCA) cycle genes blocks progression through the first mitotic division in Caenorhabditis elegans embryos. Proc Natl Acad Sci U S A. 2014 Feb 18; 111 (2014 Feb 18; 7; 111):2602-7. [Full Text/Abstract]
    Heald R, Cohen-Fix O. Morphology and function of membrane-bound organelles. Curr Opin Cell Biol. 2014 Feb; 26 (2014 Feb; 26):79-86. [Full Text/Abstract]
    Walters AD, Bommakanti A, Cohen-Fix O. Shaping the nucleus: factors and forces. J Cell Biochem. 2012 Sep; 113 (113; 2012 Sep; 9):2813-21. [Full Text/Abstract]
    Witkin KL, Chong Y, Shao S, Webster MT, Lahiri S, Walters AD, Lee B, Koh JL, Prinz WA, Andrews BJ, Cohen-Fix O. The budding yeast nuclear envelope adjacent to the nucleolus serves as a membrane sink during mitotic delay. Curr Biol. 2012 Jun 19; 22 (2012 Jun 19; 12; 22):1128-33. [Full Text/Abstract]
    Joseph-Strauss D, Gorjánácz M, Santarella-Mellwig R, Voronina E, Audhya A, Cohen-Fix O. Sm protein down-regulation leads to defects in nuclear pore complex disassembly and distribution in C. elegans embryos. Dev Biol. 2012 May 15; 365 (2012 May 15; 2; 365):445-57. [Full Text/Abstract]
    Cohen-Fix O. Orna Cohen-Fix: playing with nuclear morphology. Interview by Caitlin Sedwick. J Cell Biol. 2012 Mar 5; 196 (2012 Mar 5; 196; 5):550-1. [Full Text/Abstract]
    Webster MT, McCaffery JM, Cohen-Fix O. Vesicle trafficking maintains nuclear shape in Saccharomyces cerevisiae during membrane proliferation. J Cell Biol. 2010 Dec 13; 191 (6; 2010 Dec 13; 191):1079-88. [Full Text/Abstract]
    Cohen-Fix O. Cell biology: Import and nuclear size. Nature. 2010 Nov 25; 468 (2010 Nov 25; 468; 7323):513-6. [Full Text/Abstract]
    Witkin KL, Friederichs JM, Cohen-Fix O, Jaspersen SL. Changes in the nuclear envelope environment affect spindle pole body duplication in Saccharomyces cerevisiae. Genetics. 2010 Nov; 186 (2010 Nov; 186; 3):867-83. [Full Text/Abstract]
    Golden A, Liu J, Cohen-Fix O. Inactivation of the C. elegans lipin homolog leads to ER disorganization and to defects in the breakdown and reassembly of the nuclear envelope. J Cell Sci. 2009 Jun 15; 122 (Pt 12; 122; 2009 Jun 15):1970-8. [Full Text/Abstract]
    Webster M, Witkin KL, Cohen-Fix O. Sizing up the nucleus: nuclear shape, size and nuclear-envelope assembly. J Cell Sci. 2009 May 15; 122 (122; 2009 May 15; Pt 10):1477-86. [Full Text/Abstract]
    Fearon P, Cohen-Fix O. The endoplasmic reticulum takes center stage in cell cycle regulation. Sci Signal. 2008 Jan 22; 1 (2008 Jan 22; 3; 1):pe4. [Full Text/Abstract]
    Martinez ED, Botos J, Dohoney KM, Geiman TM, Kolla SS, Olivera A, Qiu Y, Rayasam GV, Stavreva DA, Cohen-Fix O. Falling off the academic bandwagon. Women are more likely to quit at the postdoc to principal investigator transition. EMBO Rep. 2007 Nov; 8 (2007 Nov; 8; 11):977-81. [Full Text/Abstract]
    de Gramont A, Barbour L, Ross KE, Cohen-Fix O. The spindle midzone microtubule-associated proteins Ase1p and Cin8p affect the number and orientation of astral microtubules in Saccharomyces cerevisiae. Cell Cycle. 2007 May 15; 6 (6; 2007 May 15; 10):1231-41. [Full Text/Abstract]
    de Gramont A, Ganier O, Cohen-Fix O. Before and after the spindle assembly checkpoint--an APC/C point of view. Cell Cycle. 2006 Sep; 5 (2006 Sep; 5; 18):2168-71. [Full Text/Abstract]
    Campbell JL, Lorenz A, Witkin KL, Hays T, Loidl J, Cohen-Fix O. Yeast nuclear envelope subdomains with distinct abilities to resist membrane expansion. Mol Biol Cell. 2006 Apr; 17 (17; 4; 2006 Apr):1768-78. [Full Text/Abstract]
    de Gramont A, Cohen-Fix O. The many phases of anaphase. Trends Biochem Sci. 2005 Oct; 30 (30; 2005 Oct; 10):559-68. [Full Text/Abstract]
    Sarin S, Ross KE, Boucher L, Green Y, Tyers M, Cohen-Fix O. Uncovering novel cell cycle players through the inactivation of securin in budding yeast. Genetics. 2004 Nov; 168 (2004 Nov; 3; 168):1763-71. [Full Text/Abstract]
    Ross KE, Cohen-Fix O. Molecular biology: cohesins slip sliding away. Nature. 2004 Jul 29; 430 (430; 6999; 2004 Jul 29):520-1. [Full Text/Abstract]
    Ross KE, Cohen-Fix O. A role for the FEAR pathway in nuclear positioning during anaphase. Dev Cell. 2004 May; 6 (6; 5; 2004 May):729-35. [Full Text/Abstract]
    Golden A, Cohen-Fix O. Getting (chromosomes) loaded--a new role for timeless. Dev Cell. 2003 Jul; 5 (2003 Jul; 5; 1):7-9. [Full Text/Abstract]