U.S. Department of Health and Human Services

 Contact Info

Tel: 602-440-6584
Email: paolo.piaggi@nih.gov

 Select Experience

  • Visiting FellowNIDDK2012-2016
  • Special VolunteerNIDDK2011-2012
  • Ph.D. in Automation, Robotics and BioengineeringUniversity of Pisa2012
  • M.S. in Biomedical EngineeringUniversity of Pisa2008
  • B.S. in Biomedical EngineeringUniversity of Pisa2006

 Related Links

  • Biomedical Engineering/Biophysics/Physics
  • Clinical Research
  • Computational Biology/Bioinformatics/Biostatistics/Mathematics
  • Epidemiology/Population Sciences
  • Genetics/Genomics


A selection of recent and significant publications can be viewed below.

Frankl J, Piaggi P, Foley JE, Krakoff J, Votruba SB. In Vitro lipolysis is associated with whole-body lipid oxidation and weight gain in humans. Obesity (Silver Spring). 2016 Nov 21; 25 (25; 2016 Nov 21; 1):207-214. [Full Text/Abstract]
Muller YL, Piaggi P, Chen P, Wiessner G, Okani C, Kobes S, Knowler WC, Bogardus C, Hanson RL, Baier LJ. Assessing variation across 8 established East Asian loci for type 2 diabetes mellitus in American Indians: Suggestive evidence for new sex-specific diabetes signals in GLIS3 and ZFAND3. Diabetes Metab Res Rev. 2016 Nov 8; (2016 Nov 8). [Full Text/Abstract]
Vinales KL, Schlögl M, Piaggi P, Hohenadel M, Graham A, Bonfiglio S, Krakoff J, Thearle MS. The Consistency in Macronutrient Oxidation and The Role for Epinephrine in the Response to Fasting and Overfeeding. J Clin Endocrinol Metab. 2016 Nov 7; (2016 Nov 7):jc20163006. [Full Text/Abstract]
Rago T, Scutari M, Loiacono V, Santini F, Tonacchera M, Torregrossa L, Giannini R, Borrelli N, Proietti A, Basolo F, Miccoli P, Piaggi P, Latrofa F, Vitti P. Low Elasticity of Thyroid Nodules on Ultrasound Elastography Is Correlated with Malignancy, Degree of Fibrosis, and High Expression of Galectin-3 and Fibronectin-1. Thyroid. 2016 Nov 3; 27 (27; 2016 Nov 3; 1):103-110. [Full Text/Abstract]
Chang DC, Piaggi P, Burkholder JE, Votruba SB, Krakoff J, Gluck ME. Higher insulin and higher body fat via leptin are associated with disadvantageous decisions in the Iowa gambling task. Physiol Behav. 2016 Oct 13; 167 (2016 Oct 13; 167):392-398. [Full Text/Abstract]
Di Bella G, Pingitore A, Piaggi P, Pizzino F, Barison A, Terrizzi A, d'angelo M, Todiere G, Quattrocchi S, Carerj S, Emdin M, Aquaro GD. Usefulness of late gadolinium enhancement MRI combined with stress imaging in predictive significant coronary stenosis in new-diagnosed left ventricular dysfunction. Int J Cardiol. 2016 Sep 19; 224 (2016 Sep 19; 224):337-342. [Full Text/Abstract]
Torregrossa L, Viola D, Sensi E, Giordano M, Piaggi P, Romei C, Materazzi G, Miccoli P, Elisei R, Basolo F. Papillary Thyroid Carcinoma With Rare Exon 15 BRAF Mutation Has Indolent Behavior: A Single-Institution Experience. J Clin Endocrinol Metab. 2016 Aug 29; 101 (101; 2016 Aug 29; 11):4413-4420. [Full Text/Abstract]
Hohenadel MG, Baier LJ, Piaggi P, Muller YL, Hanson RL, Krakoff J, Thearle MS. The impact of genetic variants on BMI increase during childhood versus adulthood. Int J Obes (Lond). 2016 Aug; 40 (2016 Aug; 40; 8):1301-9. [Full Text/Abstract]
Di Bella G, Minutoli F, Piaggi P, Casale M, Mazzeo A, Zito C, Oreto G, Baldari S, Vita G, Pingitore A, Khandheria BK, Carerj S. Quantitative Comparison Between Amyloid Deposition Detected by (99m)Tc-Diphosphonate Imaging and Myocardial Deformation Evaluated by Strain Echocardiography in Transthyretin-Related Cardiac Amyloidosis. Circ J. 2016 Aug 1; 80 (80; 2016 Aug 1; 9):1998-2003. [Full Text/Abstract]
Romei C, Casella F, Tacito A, Bottici V, Valerio L, Viola D, Cappagli V, Matrone A, Ciampi R, Piaggi P, Ugolini C, Torregrossa L, Basolo F, Materazzi G, Vitti P, Elisei R. New insights in the molecular signature of advanced medullary thyroid cancer: evidence of a bad outcome of cases with double RET mutations. J Med Genet. 2016 Jul 28; (2016 Jul 28). [Full Text/Abstract]
Schlögl M, Piaggi P, Pannacciuli N, Bonfiglio SM, Krakoff J, Thearle MS. Energy Expenditure Responses to Fasting and Overfeeding Identify Phenotypes Associated With Weight Change. Diabetes. 2015 Nov; 64 (64; 2015 Nov; 11):3680-9. [Full Text/Abstract]
Gluck ME, Alonso-Alonso M, Piaggi P, Weise CM, Jumpertz-von Schwartzenberg R, Reinhardt M, Wassermann EM, Venti CA, Votruba SB, Krakoff J. Neuromodulation targeted to the prefrontal cortex induces changes in energy intake and weight loss in obesity. Obesity (Silver Spring). 2015 Nov; 23 (23; 2015 Nov; 11):2149-56. [Full Text/Abstract]
Piaggi P, Thearle MS, Krakoff J, Votruba SB. Higher Daily Energy Expenditure and Respiratory Quotient, Rather Than Fat-Free Mass, Independently Determine Greater ad Libitum Overeating. J Clin Endocrinol Metab. 2015 Aug; 100 (100; 8; 2015 Aug):3011-20. [Full Text/Abstract]
Piaggi P, Thearle MS, Bogardus C, Krakoff J. Fasting hyperglycemia predicts lower rates of weight gain by increased energy expenditure and fat oxidation rate. J Clin Endocrinol Metab. 2015 Mar; 100 (100; 3; 2015 Mar):1078-87. [Full Text/Abstract]
Votruba SB, Thearle MS, Piaggi P, Knowler WC, Hanson RL, Krakoff J. Weight maintenance from young adult weight predicts better health outcomes. Obesity (Silver Spring). 2014 Nov; 22 (2014 Nov; 22; 11):2361-9. [Full Text/Abstract]
Muller YL, Thearle MS, Piaggi P, Hanson RL, Hoffman D, Gene B, Mahkee D, Huang K, Kobes S, Votruba S, Knowler WC, Bogardus C, Baier LJ. Common genetic variation in and near the melanocortin 4 receptor gene (MC4R) is associated with body mass index in American Indian adults and children. Hum Genet. 2014 Nov; 133 (133; 2014 Nov; 11):1431-41. [Full Text/Abstract]
Muller YL, Piaggi P, Hoffman D, Huang K, Gene B, Kobes S, Thearle MS, Knowler WC, Hanson RL, Baier LJ, Bogardus C. Common genetic variation in the glucokinase gene (GCK) is associated with type 2 diabetes and rates of carbohydrate oxidation and energy expenditure. Diabetologia. 2014 Jul; 57 (7; 2014 Jul; 57):1382-90. [Full Text/Abstract]
Schlögl M, Piaggi P, Thiyyagura P, Reiman EM, Chen K, Lutrin C, Krakoff J, Thearle MS. Overfeeding over 24 hours does not activate brown adipose tissue in humans. J Clin Endocrinol Metab. 2013 Dec; 98 (2013 Dec; 98; 12):E1956-60. [Full Text/Abstract]
Piaggi P, Krakoff J, Bogardus C, Thearle MS. Lower "awake and fed thermogenesis" predicts future weight gain in subjects with abdominal adiposity. Diabetes. 2013 Dec; 62 (2013 Dec; 12; 62):4043-51. [Full Text/Abstract]