U.S. Department of Health and Human Services
Peter McPhie

 Contact Info

Tel: 301-496-5890
Email: pmcphie@helix.nih.gov

 Select Experience

  • Staff ScientistLaboratory of Biochemistry and Genetics, NIDDK, NIH1990–Present
  • Visiting ScientistLaboratory of Biological Modeling, NIDDK, NIH1968–1990
  • Postdoctoral FellowStanford University Medical School1966–1968
  • Ph.D.King’s College, University of London1966
  • B.Sc.King’s College, University of Durham1963

 Related Links


    • Structural Biology


    A selection of recent and significant publications can be viewed below.

    Backus KM, Dolan MA, Barry CS, Joe M, McPhie P, Boshoff HI, Lowary TL, Davis BG, Barry CE 3rd. The Three Mycobacterium tuberculosis Antigen 85 Isoforms Have Unique Substrates and Activities Determined by Non-active Site Regions. J Biol Chem. 2014 Jul 14; 289 (2014 Jul 14; 36; 289):25041-53. [Full Text/Abstract]
    Chagas AC, McPhie P, San H, Narum D, Reiter K, Tokomasu F, Brayner FA, Alves LC, Ribeiro JM, Calvo E. Simplagrin, a platelet aggregation inhibitor from Simulium nigrimanum salivary glands specifically binds to the Von Willebrand factor receptor in collagen and inhibits carotid thrombus formation in vivo. PLoS Negl Trop Dis. 2014 Jun; 8 (6; 8; 2014 Jun):e2947. [Full Text/Abstract]
    Zhang M, Khripin CY, Fagan JA, McPhie P, Ito Y, Zheng M. Single-step total fractionation of single-wall carbon nanotubes by countercurrent chromatography. Anal Chem. 2014 Apr 15; 86 (86; 8; 2014 Apr 15):3980-4. [Full Text/Abstract]
    McPhie P. Concentration-independent estimation of protein secondary structure by circular dichroism: a comparison of methods. Anal Biochem. 2008 Apr 15; 375 (375; 2; 2008 Apr 15):379-81. [Full Text/Abstract]
    McPhie P, Ni YS, Minton AP. Macromolecular crowding stabilizes the molten globule form of apomyoglobin with respect to both cold and heat unfolding. J Mol Biol. 2006 Aug 4; 361 (2006 Aug 4; 1; 361):7-10. [Full Text/Abstract]
    McPhie P. CD studies on films of amyloid proteins and polypeptides: quantitative g-factor analysis indicates a common folding motif. Biopolymers. 2004 Oct 5; 75 (2; 2004 Oct 5; 75):140-7. [Full Text/Abstract]
    Sasahara K, McPhie P, Minton AP. Effect of dextran on protein stability and conformation attributed to macromolecular crowding. J Mol Biol. 2003 Feb 28; 326 (2003 Feb 28; 326; 4):1227-37. [Full Text/Abstract]