U.S. Department of Health and Human Services
Rafael Daniel Camerini-Otero

 Contact Info

Tel: 301-496-2710
Email: rc10d@nih.gov

 Select Experience

  • M.D., Ph.D.New York University1973
  • B.S.Massachusetts Institute of Technology1966

 Related Links


Rafael Daniel Camerini-Otero, M.D., Ph.D.

Chief, Genetics and Biochemistry Branch
Section Chief, Genetics and Biochemistry SectionGenetics and Biochemistry Branch
  • Chromosome Biology/Epigenetics
  • Computational Biology/Bioinformatics/Biostatistics/Mathematics
  • Genetics/Genomics
  • Molecular Biology/Biochemistry
  • Systems Biology
Research Summary/In Plain Language

Research Summary

Research Goal

The ultimate goal of our research is to improve the health of individuals with inherited and congenital conditions and diseases.

Current Research

My laboratory is interested in the biochemistry and molecular biology of homologous recombination in prokaryotes and eukaryotes.  The focus had been on the first homology-dependent step in homologous recombination, the homologous pairing of DNAs.  We have been studying the underlying biochemical mechanism to understand the biology of genetic recombination and to devise new strategies to manipulate complex genomes in vitro and, in the future, in vivo, and the DNA-protein complexes involved.  In addition, we have been studying the biochemistry and molecular biology of mouse meiosis and evolutionary genomics.  Most recently, we have been investigating novel approaches to map recombination hotspots in a variety of mammals including humans.​