U.S. Department of Health and Human Services
Ranganath Muniyappa

 Contact Info

Tel: 301-451-7702
Email: muniyapr@mail.nih.gov

 Select Experience

  • FellowshipState University of New York (SUNY)2001–2004
  • ResidencyWayne State University Program1998–2001
  • Ph.D.Wayne State University1999
  • M.D.Bangalore Medical College1991

 Related Links


    Ranganath Muniyappa, M.D., Ph.D.

    Senior Research Physician, Clinical Endocrinology SectionDiabetes, Endocrinology, and Obesity Branch
    Director, Inter-Institute Endocrinology Fellowship Program
    • Cell Biology/Cell Signaling
    • Clinical Research
    • Health Disparities
    Research Summary/In Plain Language

    Research Summary

    Research Goal

    Our ultimate goal is to develop effective therapies that simultaneously target metabolic and vascular dysfunction in obesity and diabetes.​

    Current Research

    Our research focuses on studies of the metabolic and vascular actions of insulin and how these actions are impaired in insulin-resistant states such as obesity, diabetes, and cardiovascular disease.  Insulin-mediated microvascular recruitment plays an important role in glucose disposal and is frequently impaired in people with obesity and diabetes.  We perform clinical studies that seek to understand how therapeutic interventions modulate biological actions of insulin and the molecular mechanisms of insulin resistance that play a role in coupling metabolic and vascular dysfunction in obesity and diabetes. Our research is also directed toward understanding the physiologic basis for the higher prevalence of cardiovascular dysfunction and insulin resistance in ethnic minorities such as African-Americans, Hispanic/Latinos, and Asians.

    Applying our Research

    Cardiovascular disease is a major cause of mortality and morbidity in diabetes. Developing novel therapies that target cardiovascular risk in obesity and diabetes will greatly benefit our patients with diabetes and obesity.