The Phoenix Epidemiology and Clinical Research Branch researches the causes of and connections among type 2 diabetes, obesity, and diabetic complications. My research focuses on the frequency and prevalence of these diseases in American Indians and other populations. I mainly study the genetic and molecular aspects of these diseases.
The branch studies potential genetic causes, such as possible DNA changes in families and populations. We also study
- gene transcription, which is the process a cell uses to create a protein;
- protein expression, which is the effect of a protein;
- cellular metabolism, which is the sum of chemical reactions in a cell; and
- how lifestyle changes that lead to weight loss can help prevent diabetes and its complications.