U.S. Department of Health and Human Services
 

 Contact Info

 
Tel: 301-496-1069
Email: sebastianp@mail.nih.gov
 

 Select Experience

 
  • Clinical FellowBaylor College of Medicine and The University of Texas M.D. Anderson Cancer Center1994–1997
  • Research RegistrarThe General Infirmary at Leeds, University of Leeds1988–1993
  • RegistrarChapel Allerton Hospital, Leeds/The General Infirmary at Leeds1987–1988
  • MRCPRoyal College of Physicians1987
  • Senior House Officer/RegistrarBury General Hospital, Manchester/ Pinderfields General Hospital1985–1987
  • FFARCSRoyal College of Surgeons1984
  • Registrar in AnaestheticsSt. Helier Hospital1983–1984
  • Senior House OfficerNorth Staffordshire Hospital Centre1982–1983
  • Senior House Officer/RegistrarSt. Martha’s  Hospital, St. John’s Medical College Hospital1979–1981
  • Ph.D.University of Leeds1994
  • M.B.B.S.St. John’s Medical College1979
 

 Related Links

 

Sebastian J. Padayatty, FFARCS, MRCP, Ph.D.

Staff Clinician, Molecular and Clinical Nutrition SectionDigestive Disease Branch
Specialties
  • Clinical Research

​Research Images

Images or videos appear below. Clicking images or videos provides an expanded view.

TitleDescriptionImage
Octreotide increases exercise capacity in patients with acromegalyThe somatostatin analogue Octreotide increases exercise capacity in patients with acromegaly.  Changes in exercise capacity [in metabolic equivalents (METS): 1 MET = energy expenditure at rest = O2 consumption of 3.5 ml. kg -1 body weight. min -1] and total exercise time at 0, 6, and 12 months are shown.Octreotide increases exercise capacity in patients with acromegalyEnlarge
Lovastatin induced apoptosis in prostate stromal cellsLovastatin (30 µmol/L) induced apoptosis in prostate stromal cells in culture.  Cells were stained with acridine orange.  Apoptotic cells (panels B and D) have small, bright, condensed, and fragmented nuclei with intact cell membranes. Lovastatin induced apoptosis in prostate stromal cellsEnlarge
SVCT1 SNPs and predicted plasma vitamin C concentrationsPredicted (using a mathematical model) plasma vitamin C concentrations in subjects carrying single nucleotide polymorphisms (SNP) for the vitamin C transporter sodium vitamin C transporter 1 (SVCT1).  Actual measured values for normal subjects are shown.  Data on SVCT1 vitamin C transport was obtained from in vitro studies.SVCT1 SNPs and predicted plasma vitamin C concentrationsEnlarge
Predicted plasma vitamin C concentrations following oral dosingPredicted (using a mathematical model) plasma vitamin C concentrations in normal subjects taking different doses of vitamin C until a steady state is reached.  The mathematical model was constructed using dose concentration data in normal volunteers. Predicted plasma vitamin C concentrations following oral dosingEnlarge
Human adrenal glands secrete vitamin CAdrenal glands secrete vitamin C when stimulated by Adrenocorticotrophic hormone.  Blood samples were obtained from both adrenals following adrenal venous catheterization. Human adrenal glands secrete vitamin CEnlarge