U.S. Department of Health and Human Services

 Contact Info

Tel: 301-496-1069
Email: sebastianp@mail.nih.gov

 Select Experience

  • Clinical FellowBaylor College of Medicine and The University of Texas M.D. Anderson Cancer Center1994–1997
  • Research RegistrarThe General Infirmary at Leeds, University of Leeds1988–1993
  • RegistrarChapel Allerton Hospital, Leeds/The General Infirmary at Leeds1987–1988
  • MRCPRoyal College of Physicians1987
  • Senior House Officer/RegistrarBury General Hospital, Manchester/ Pinderfields General Hospital1985–1987
  • FFARCSRoyal College of Surgeons1984
  • Registrar in AnaestheticsSt. Helier Hospital1983–1984
  • Senior House OfficerNorth Staffordshire Hospital Centre1982–1983
  • Senior House Officer/RegistrarSt. Martha’s  Hospital, St. John’s Medical College Hospital1979–1981
  • Ph.D.University of Leeds1994
  • M.B.B.S.St. John’s Medical College1979

 Related Links


Sebastian J. Padayatty, FFARCS, MRCP, Ph.D.

Staff Clinician, Molecular and Clinical Nutrition SectionDigestive Disease Branch
  • Clinical Research
Research Summary/In Plain Language

Research Summary

Research Goal

Our goals are to determine the optimum intake of essential nutrients and the best diet that can maintain and promote good health.

Current Research

Our investigations focus on vitamin C physiology in normal subjects and in those with disease. We are investigating the relationship between dose (or daily intake) and the blood and tissue concentrations of vitamins C and E. Data on dose concentration relationship is essential to the conduct and interpretation of clinical studies. An additional area of investigation is intestinal glucose absorption and factors that modify it.​

Applying our Research

In the short term, data from dose concentration and pharmacokinetic studies can be used to formulate dietary recommendations and to improve the design of clinical studies. In the long term, our research will increase knowledge, and may help us make wise choices with regard to the foods we eat.

Need for Further Study

We need to study what the ideal intake of vitamins (micro nutrients) is as well as that of proteins, fat, and carbohydrates (macro nutrients) in healthy people and in those with disease.