U.S. Department of Health and Human Services
Individualizing Treatment - Broadening the Framework for Urinary Incontinence Research

Individualizing Treatment - Broadening the Framework for Urinary Incontinence Research

3/30/2017 12:00 AM
3/31/2017 12:00 AM
Yes
No

Program Content

Tamara Bavendam, M.D., M.S.
NIDDK
T: 301-594-4733
E: tamara.bavendam@nih.gov

Meeting Logistics

Mark Dennis
The Scientific Consulting Group, Inc.
T: 301-670-4990
E: mdennis@scgcorp.com ​​
Bethesda
 
Natcher Conference Center

Event Details

Background

While treatment options exist for people with urinary incontinence (UI), outcomes vary and there is insufficient information about the individual biologic and non-biologic factors that might affect treatment success. More tailored approaches may help clinicians initiate the optimal UI treatment for a specific patient.

Meeting Purpose

This is the first of two meetings to be held in 2017. The overarching goal of the meeting series is to develop fundable, interdisciplinary, investigator-initiated research proposals that will lead to better outcomes for currently available treatments by individualizing them to each patient, considering characteristics across the spectrum from biology to the social determinants of health.

Depicting the various factors that affect urinary incontinence: Social Determinants of Health (e.g., socioeconomic status, acces 

Adopting this broader framework for research will require engaging researchers from scientific fields beyond urology. We encourage participants to get outside of their comfort zones and think broadly about what factors might be involved in successful treatment outcomes. The goal will be to identify as many factors as possible, working in interdisciplinary groups to shape research questions.

The first meeting will set the stage on the status of existing treatments and the factors that may predict treatment success, and it will encourage participants to brainstorm research questions and approaches. The second meeting, to be held in Summer or Fall 2017, will focus on refining and focusing research approaches.

Meeting Objectives

As a first step toward achieving personalized medicine in UI, the National Institutes of Health is hosting a meeting on March 30 and 31, 2017 to:

  • Enhance interdisciplinary thinking among specialties involved in UI research—including pelvic medicine and reconstructive surgeons, urologists, obstetrician-gynecologists, primary care clinicians, geriatricians, nursing professionals, physical therapists, occupational therapists, behavioral scientists, pharmacists, bioengineers, geneticists and microbiologists—identify gaps in the evidence that would support personalized treatment in individuals with UI.
  • Learn how individualized treatment is evolving in other disciplines and its impact on these fields.
  • Consider strategies to identify the most effective treatment for an individual, considering biologic (e.g., anatomy, physiology, immunology, microbiome) and non-biologic (e.g., preferences, beliefs, cognitive ability, education, employment, etc.) factors.
  • Help participants forge interdisciplinary teams and generate testable hypotheses that will fill specific knowledge gaps in our ability to provide UI treatment tailored to the individual.

Participants are encouraged to attend with colleagues from their institutions with diverse areas of expertise to facilitate interdisciplinary research planning.

Registration Deadline

March 24, 2017​​​​​​​

Agenda

March 30, 2017

   
12:30 p.m. – 12:40 p.m. Introduction
Dr. Tamara Bavendam
   
12:40 p.m. – 1:50 p.m. Panel: Basics of anatomy and function. Where are we now with UI treatment?
Moderator: Dr. Eric Rovner
Dr. Michael Albo
Dr. Cindy Amundsen
Dr. Mikel Gray
   
  Topics to be discussed include overview of anatomy and physiology of continence; pathophysiology of incontinence in females, males and neurogenic populations, current treatment options.
   
1:50 p.m. – 2:00 p.m. Welcome from NIDDK Director
Dr. Griffin Rodgers
   
2:00 p.m. – 2:15 p.m. Break
   
2:15 p.m. – 4:00 p.m. Panel: What (nontraditional) factors might affect UI treatment success?
Moderator: Dr. Lisa Begg
Dr. Jennifer Hebert-Beirne (social determinants)
Dr. Carol Musil (cognitive processing)
Dr. Colleen Fitzgerald (musculoskeletal)
Dr.Catherine Bradley (review of nonurologic factors)
Dr. Jeffrey Henderson (urine constituents)
   
4:00 p.m. – 4:45 p.m. Panel: How are other fields starting to individualize treatment?
Moderator: Dr. Marcel Salive
Dr. Theodore Johnson (geriatrics)
Dr. Christopher Schmid (statistics)
   
4:45 p.m. – 5:15 p.m. Questions and Answers
   
5:15 p.m. – 6:00 p.m. Poster Session
   
7:00 p.m. Group Dinners (optional) – Leave from Hyatt
   

March 31, 2017

   
8:00 a.m. – 8:45 a.m. Panel: Building successful transdisciplinary teams/Conceptual Models
Moderator: Dr. Tamara Bavendam
Dr. Sonya Brady
Dr. Linda Brubaker
   
8:45 a.m. – 9:00 a.m. Break (move to Small Group Sessions)
   
9:00 a.m. – 12:00 p.m. Small Group Sessions
   
  Brainstorm and ideate research questions that will address how a variety of factors—including local and systemic biologic, behavioral, cognitive, and social determinants—may affect treatment success across treatment types and populations
   
12:00 p.m. – 12:30 p.m. Lunch
   
12:30 p.m. – 2:30 p.m. Small Group Report Back and Discussion
Moderators: Dr. Tamara Bavendam, Dr. Sonya Brady, Dr. Lisa Halvorson
   
2:30 p.m. Wrap Up and Adjournment
 

Directions/Travel

Hotel Accommodations

Hyatt Regency Bethesda Hotel
One Bethesda Metro Center
7400 Wisconsin Avenue
Bethesda, MD 20814
Telephone: (301) 657-1234 or (888) 421-1442
Fax: (301) 657-6453

Website: http://www.hyattregencybethesda.com
(More hotel information can be obtained from this website.)

Government Room Rate

A limited block of sleeping rooms for meeting participants has been reserved at the Hyatt Regency Bethesda. The rate is the prevailing government rate of $242 per night for single occupancy, plus tax (13%). To reserve a hotel room at the group rate, click on this link: https://aws.passkey.com/go/N1DD The room block will be in effect at the Government rate only until Tuesday, February 28, 2017, or until full, whichever comes first. Any room reservations received after this date will be accepted on a space- and rate-availability basis. Please be certain that the hotel provides you with a confirmation number for your reservation.

Reservation Dates

Book your arrival date as Thursday, March 30, 2017, and departure as Friday, March 31, 2017. If you require alternate dates, please contact Mark Dennis of The Scientific Consulting Group, Inc. (SCG).

Check-in

When making a reservation, please provide your room and bedding preferences. The hotel will assign specific room types at check-in, based on availability. Please be advised that requests are not guaranteed. Check-in time is 4:00 p.m., and checkout time is 12:00 p.m.

Cancellations

If you need to cancel your reservation, please do so by 4:00 p.m. on the day prior to arrival, or your credit card will be charged for 1 night as a no-show fee.

NIH Visitor Information

Information on visiting the NIH, campus maps, shuttle schedules, driving directions, security, and more can be found on the NIH Visitor Information page. ​

Minutes

Minutes are currently unavailable.

Attendees

Speakers

Michael Albo, M.D., Professor, Department of Surgery/Urology, University of California, San Diego, San Diego, CA

Cindy Amundsen, M.D., Professor, Department of Obstetrics and Gynecology/Urogynecology, Duke University, Raleigh, NC

Catherine Bradley, M.D., MSCE, Associate Professor, Department of Obstetrics and Gynecology/Urogynecology, University of Iowa, Iowa City, IA

Sonya Brady, Ph.D., Associate Professor, Department of Psychology, School of Public Health, University of Minnesota, Minneapolis, MN

Colleen Fitzgerald, M.D. Associate Professor, Department of Physical Medicine and Rehabilitation, Loyola University Chicago, Chicago, IL

Mikel Gray, Ph.D., Professor, School of Nursing, University of Virginia, Charlottesville, VA

Jeffrey Henderson, M.D., Ph.D., Assistant Professor, Department of Infectious Disease and Molecular Biology, Washington University in St. Louis, St. Louis, MO

Jennifer Hebert-Beirne, Ph.D., M.P.H., Assistant Professor, School of Public Health, University of Illinois at Chicago, Chicago, IL

Theodore Johnson, M.D., M.P.H., Professor, School of Medicine, Division of Geriatrics, Emory University, Atlanta, GA

Carol Musil, Ph.D., R.N., Professor, School of Nursing, Case Western Reserve University, Cleveland, OH

Christopher Schmid, Ph.D., Professor, Department of Biostatistics, Brown University, Providence, RI

Planning Committee

Tamara Bavendam, M.D., Senior Scientific Officer, Division of Kidney, Urology, and Hematology Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD

Lisa Begg, Ph.D., R.N., Senior Research Program Officer, Office of Research on Women’s Health, National Institutes of Health, Bethesda, MD

Linda Brubaker, M.D., M.S., Health Sciences Clinical Professor, Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Reproductive Medicine, University of California, San Diego, San Diego, CA

Allison Cernich, Ph.D., Director, National Center for Medical Rehabilitation Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD

William Elwood, Ph.D., Health Science Administrator, Office of Behavioral and Social Sciences, National Institutes of Health, Bethesda, MD

Daniel Gossett, Ph.D., Program Director, Division of Kidney, Urology, and Hematology Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD

Lisa Halvorson, M.D., Chief, Gynecologic Health and Disease Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD

Jenna Norton, M.P.H., Director, Kidney and Urology Science Translation Program, Division of Kidney, Urology and Hematology Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD

Eric Rovner, M.D., Professor, Department of Urology (Pelvic Floor Medicine and Reconstructive Surgery), Medical University of South Carolina, Charleston, SC

Marcel Salive, M.D., M.P.H., Program Officer, Division of Geriatrics and Clinical Gerontology, National Institute on Aging, Bethesda, MD ​

Abstracts

Abstracts

Attendees are invited to submit abstracts for posters to be presented at the end of the first day. Posters can be of two varieties:

  • Traditional—Presenting research that can improve our ability to individualize treatment for patients with urinary incontinence. Posters do not need to focus on treatment of urinary incontinence.
  • Idea Generating—Building the case for a factor that might affect treatment outcomes and help target treatments, including why it should be considered in research.

The goal of the poster session will be to stimulate interdisciplinary thinking and create additional ideas to prepare for small group discussions the following day.

Following the poster session, there will be opportunities for small groups of individuals to go out to dinner to continue the discussions.

Location

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  • Building 45
  • 45 Center Drive, NIH Campus
  • MD 20894
Webinar

Contacts

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Program Content

Tamara Bavendam, M.D., M.S.
NIDDK
T: 301-594-4733
E: tamara.bavendam@nih.gov

Meeting Logistics

Mark Dennis
The Scientific Consulting Group, Inc.
T: 301-670-4990
E: mdennis@scgcorp.com ​​