U.S. Department of Health and Human Services
Sex and the Kidneys: Sex Differences in Renal Disease

Sex and the Kidneys: Sex Differences in Renal Disease

7/13/2017 7:00 AM
7/14/2017 4:30 PM
Yes
No
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Program Content

Tracy Rankin, Ph.D.
Program Director
NIDDK
T: 301-594-4748
E: rankint@mail.nih.gov

Meeting Logistics

Mark Dennis
The Scientific Consulting Group, Inc.
T: 301-670-4990
E: mdennis@scgcorp.com
Bethesda
 
Natcher Conference Center

Event Details

Background

In 1999, the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) convened a workshop, Women in Renal Disease, that focused on identifying the unique risks of Chronic Kidney Disease (CKD) and progression to end-stage renal disease present in women across their lifespans. At the conclusion of the workshop, the workshop organizers proposed several avenues of research to advance our understanding of the pathophysiology of sex differences in CKD and improve clinical care of women with CKD. While some advances have been made in both clinical and basic research, much remains poorly understood, both at the molecular and clinical level.

Meeting Objectives

The NIH has recently re-focused the investigator community on the role of sex as a biological variable—requiring all research grant submissions to deliberately consider sex as a modifier of biological response. The purpose of this workshop is to afford the renal research community an opportunity to re-visit the role of sex in disease risk and etiology and take advantage of the advances made in our understanding of sex steroid action in somatic tissues, as well as understanding the role of sex chromosome complement in disease pathophysiology.

Organizing Committee

Dr. Paul Kimmel, NIDDK/NIH
Dr. Tracy Rankin, NIDDK/NIH
Dr. Ken Korach, NIEHS/NIH
Dr. Louis DePaolo, NICHD/NIH
Dr. Lisa Begg, ORWH/NIH
Dr. Sharon Anderson, Oregon Health Sciences University
Dr. Kathryn Sandberg, Georgetown University
Dr. Jennifer C. Sullivan, Georgia Regents University
Dr. Julie Ingelfinger, Harvard University

Registration Deadline

July 07, 2017

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Agenda

July 13, 2017

   
7:00 – 8:00 a.m. Registration
   
8:00 – 8:15 a.m. Opening Remarks and Objectives Auditorium
   
8:15 – 10:20 a.m. SESSION 1: Molecular Endocrinology of Sex Steroid Action
   
  Moderator and Introduction
Tracy Rankin, Ph.D., NIDDK
   
  Current Understanding and Unknowns in Estrogen Action
Kenneth Korach, Ph.D., National Institute of Environmental Health Sciences
   
  Current Understanding and Unknowns in Androgen Action
Stephen Hammes, M.D., Ph.D., University of Rochester Medical Center
   
  Therapeutic Modulators of Estrogen and Androgen Actions
Carolyn Smith, Ph.D., Baylor College of Medicine
   
  Role of Sex Chromosomes in Sex Differences
Christine Disteche, Ph.D., University of Washington
   
10:20 – 10:40 a.m. Break
   
10:40 – 12:40 p.m. SESSION 2: Biology and Epidemiology of Sex Differences—
Lessons from other Systems
Auditorium
   
  Moderator
Julie Ingelfinger, M.D., MassGeneral Hospital for Children (tentative)
   
  Cardiovascular Disease and Bone Health
C. Noel Bairey Merz, M.D., FACC, Cedars-Sinai Medical Center
   
  Diabetes and Obesity
Franck Mauvais-Jarvis, M.D., Ph.D., Tulane University School of Medicine
   
  Interactions with Race/Ethnicity
Ana Ricardo, M.D., M.P.H., M.S., University of Illinois College of Medicine at Chicago
   
  Microbiome and Sex Differences
James Morton, Ph.D., University of California, San Diego
   
12:40 – 1:40 p.m. Lunch
   
1:40 – 3:50 p.m. Breakout Sessions
   
  Session 1: Basic Science Needs
Session Leaders: Tracy Rankin, Ph.D., NIDDK
Jennifer Sullivan, Ph.D., FAHA, Augusta University
Balcony A
   
  Session 2: Translational Approaches
Session Leaders: Julie Ingelfinger, M.D., Massachusetts General Hospital
Christine Maric-Bilkan, Ph.D., National Heart, Lung, and Blood Institute
Balcony B
   
  Session 3: Needed Methods/Tools
Session Leader: Kathryn Sandberg, Ph.D., Georgetown University Medical Center
Balcony C
   
  Session 4: Clinical Research Needs/Approaches
Session Leader: Laura Dember, M.D., University of Pennsylvania
Auditorium
   
3:50 – 4:10 p.m. Break
   
4:10 – 5:30 p.m. Breakout Sessions—Reports and Group Discussion Auditorium
   
  Breakout Sessions Reports
   
4:10 – 4:30 p.m.
4:30 – 4:50 p.m.
4:50 – 5:10 p.m.
5:10 – 5:30 p.m.
Breakout Session 1
Breakout Session 2
Breakout Session 3
Breakout Session 4
   
5:30 – 6:00 p.m. Cross-Arching Group Discussion
   
6:00 p.m. Day 1 Adjournment
   

July 14, 2017

   
8:00 – 8:30 a.m. Registration
   
8:30 – 10:30 a.m. SESSION 3: Renal Disease: Basic Mechanisms and Clinical Manifestation Auditorium
   
  Moderator
Paul Kimmel, M.D., M.A.C.P., NIDDK
   
  Cellular Aspects
James Fuscoe, Ph.D., U.S. Food and Drug Administration
   
  Clinical Aspects
Joel Neugarten M.D., J.D., Albert Einstein College of Medicine
   
  Sex Differences in Transplantation Outcomes
Amanda Miller, M.D., Dalhousie University
   
  Women and Hypertension
Vesna Garovic, M.D., Mayo Clinic
   
10:30 – 10:45 a.m. Break
   
10:45 – 12:00 p.m. SESSION 4: Approaches and Tools to Interrogate and Treat Sex Differences Auditorium
   
  Moderator
Kathryn Sandberg, Ph.D., Georgetown University Medical Center
   
  Design of Pre-Clinical Studies to Account for Sex Differences
Janine Clayton, M.D., Director, Office of Research on Women’s Health, NIH
   
  Novel Renal Imaging Modalities
Jennifer Charlton, M.D., University of Virginia School of Medicine
   
  Precision Medicine Approaches to Design Sex-Specific Therapies
Virginia Miller, Ph.D., Mayo Clinic
   
12:00 – 1:00 p.m. Lunch
   
1:00 – 2:40 p.m. Breakout Sessions
   
  Session 1: Basic Science Needs
Session Leader(s): Tracy Rankin, Ph.D., NIDDK
Jennifer Sullivan, Ph.D., FAHA, Augusta University
Balcony A
   
  Session 2: Translational Approaches
Session Leader(s): Julie Ingelfinger, M.D., Massachusetts General Hospital
Christine Maric-Bilkan, Ph.D., National Heart, Lung, and Blood Institute
Balcony B
   
  Session 3: Needed Methods/Tools
Session Leader: Kathryn Sandberg, Ph.D., Georgetown University Medical Center
Balcony C
   
  Session 4: Clinical Research Needs/Approaches
Session Leader: Laura Dember, M.D., University of Pennsylvania
Auditorium
   
2:40 – 3:00 p.m. Break
   
3:00 – 4:20 p.m. Breakout Sessions—Reports and Group Discussion Auditorium
   
  Breakout Sessions Reports
   
3:00 – 3:20 p.m.
3:20 – 3:40 p.m.
3:40 – 4:00 p.m.
4:00 – 4:20 p.m.
Breakout Session 1
Breakout Session 2
Breakout Session 3
Breakout Session 4
   
4:20 – 4:30 p.m. Cross-Arching Group Discussion and Closing Remarks Auditorium
   
4:30 p.m. Adjournment
   

Directions/Travel

Untitled Document

Hotel Accommodations

Bethesda Marriott Hotel
5151 Pooks Hill Road
Bethesda, MD  20814
Phone:  (301) 897-9400 or (800) 228-9290

Website:  http://www.marriott.com/hotels/travel/wasbt-bethesda-marriott
(More hotel information can be obtained from this website.)

Government Room Rate

A limited block of sleeping rooms for meeting participants has been reserved at the Bethesda Marriott. The rate is the prevailing government rate of $172 per night for single occupancy, plus tax (13%). To reserve a hotel room at the group rate, call Reservations at (800) 393-3412 or toll free at (800) 228-9290 and identify yourself as a member of the Sex Differences in Renal Disease Meeting. You may also reserve your room via Passkey.

The room block will be in effect at the Government rate only until Wednesday, June 28, 2017, or until full, whichever comes first. Any room reservations received after this date will be accepted on a space and rate-availability basis.

Reservation Dates

Book arrival for Wednesday, July 12, 2017, and departure on Friday, July 14, 2017. If you require alternate dates, please contact Mark Dennis of The Scientific Consulting Group, Inc. (SCG).

Check-in

Please be certain that the hotel provides you with a confirmation number for your reservation. After the Wednesday, June 28, 2017 deadline, the official room block will be released, and the hotel may charge significantly higher rates and may be sold out. When making a reservation, please provide your room and bedding preferences. The hotel will assign specific room types at check-in, based on availability. Please be advised that requests are not guaranteed. Check-in time at the hotel is 4:00 p.m., and checkout time is 12:00 p.m.

Cancellations

If you need to cancel your reservation, please do so no later than 72 hours prior to arrival, or you will be charged a no-show fee for 1 night on your credit card.

NIH Visitor Information 

Information on visiting the NIH, campus maps, shuttle schedules, driving directions, security, and more can be found on the NIH Visitor Information page. ​

Minutes

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Attendees

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Abstracts

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Location

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  • Building 45
  • MD 20894
Webinar

Contacts

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Program Content

Tracy Rankin, Ph.D.
Program Director
NIDDK
T: 301-594-4748
E: rankint@mail.nih.gov

Meeting Logistics

Mark Dennis
The Scientific Consulting Group, Inc.
T: 301-670-4990
E: mdennis@scgcorp.com