U.S. Department of Health and Human Services

Individualizing Treatment for Urinary Incontinence - Evolving Research Questions into Research Plans

2/1/2018 7:00 AM
2/2/2018 2:30 PM
Yes
No

Program Content

Tamara Bavendam, M.D., M.S.
NIDDK
T: 301-594-4733

Meeting Logistics

Mark Dennis
The Scientific Consulting Group, Inc.
T: 301-670-4990
Bethesda
 
Natcher Conference Center

Event Details

Background

Although treatment options exist for people with urinary incontinence (UI), outcomes vary and there is insufficient information about the individual biologic and non-biologic factors that might affect treatment success, behaviors, and individual quality of life. With a variety of potential approaches, shared decision making is important to develop a treatment strategy that aligns with an individual’s preferences and goals of care and behaviors. All affected populations—female, male, children, neurogenic (congenital or acquired)—can benefit from individualized treatment approaches.

In March 2017, the National Institutes of Health (NIH) hosted Individualizing Treatment—Broadening the Framework for Urinary Incontinence Research, where participants reviewed numerous biologic and non-biologic factors that may influence individual treatment success and identified hypotheses and research questions to build the knowledge base that will enable better targeting of existing treatments to appropriate persons with UI. Read the March 2017 meeting summary (PDF, 502 KB).

Meeting Purpose

The goal of this meeting is to build on the ideas generated by the March 2017 meeting to develop fundable, interdisciplinary, investigator-initiated research proposals that will lead to better outcomes for currently available treatments by individualizing them to each patient, considering characteristics across the spectrum from biology to the social determinants of health. Adopting this broader framework for research will require engaging researchers from scientific fields beyond urology.

Depicting the various factors that affect urinary incontinence: Social Determinants of Health (e.g., socioeconomic status, etc.) 

Meeting Objectives

  • Enhance interdisciplinary thinking among specialists and those with interest and involvement in UI research, including pelvic medicine and reconstructive surgeons, urologists, obstetrician-gynecologists, geriatricians, pediatricians, behavioral scientists, basic scientists, engineers, nurses, physical therapists, occupational therapists, administrators, and economists.
  • Expand participant understanding of the role of basic science, engineering, behavioral science, and clinical science in individualizing treatment for persons with UI and how it affects their caregivers and community.
  • Inform participants of novel research methodologies that can be used to study individualizing treatment and examine outcomes.
  • Discuss opportunities to involve families, peers, and other social network members of people with UI into research, treatment, and ongoing care.
  • Guide interdisciplinary research teams in the development of actionable research plans that will enable improved targeting of existing or novel UI treatments.
  • Provide time for research teams to confer with experts in clinical trial methodology and biostatistics regarding their research strategy.

Participants are encouraged to invite and bring colleagues from their institutions with diverse areas of expertise to facilitate interdisciplinary research planning. Having attended the March 2017 meeting is not necessary for participants to engage in or benefit from the February 2018 meeting. Participants are encouraged to review the Executive Summary of the March 2017 meeting at the link above.

Registration Deadline

January 26, 2018​​

Agenda

A detailed agenda will be posted in the near future. The following provides a high-level outline of the meeting. Note: the order of the sessions may change in the final agenda.

February 1, 2018

   
7:00 a.m. – 8:00 a.m. Mentorship Breakfast
   
8:00 a.m. – 11:40 a.m. Optional Pre-meeting Workshop: Establishing a Research Career in Benign Urologic Conditions
   
11:40 a.m. – 12:30 p.m. Lunch
   
12:30 p.m. – 3:00 p.m. Welcome and Novel Research Methodologies
   
3:00 p.m. – 3:15 p.m. Break
   
3:15 p.m. – 4:45 p.m. Identifying and Working with Collaborators
   
4:45 p.m. – 5:30 p.m. Collaborator Elevator Pitches
(Share your idea and partnership needs in 2 minutes or less)
   
5:30 p.m. – 6:30 p.m. Poster Session
   
6:30 p.m. – 8:30 p.m. Networking Dinners
   

February 2, 2018

   
8:00 a.m. – 9:00 a.m. Mentorship Breakfast
   
9:00 a.m. – 11:00 a.m. Translational Pathway for Individualized Therapies
   
11:00 a.m. – 11:15 a.m. Break
   
11:15 a.m. – 1:15 p.m. Team-based Research Planning Session and Working Lunch
   
1:15 p.m. – 1:30 p.m. Meeting Adjournment
   
1:30 p.m. – 2:30 p.m. Post-meeting Expert Consultation Sessions
(Sign up for feedback from NIH staff and senior investigators)

Directions/Travel

Hotel Accommodations

One Bethesda Metro Center
7400 Wisconsin Avenue
Bethesda, MD 20814
Phone:  (301) 657-1234 or (888) 421-1442

Government Room Rate

A limited block of sleeping rooms for meeting participants has been reserved at the Hyatt Regency Bethesda. The rate is the prevailing government rate of $201 per night for single occupancy, plus tax (13%). The room block will be in effect at the Government rate only until Wednesday, January 3, 2018, or until full, whichever comes first. Any room reservations received after this date will be accepted on a space- and rate-availability basis. Please be certain that the hotel provides you with a confirmation number for your reservation.

Reservation Dates

Book your arrival date as Thursday, January 31, 2018, and departure as Friday, February 2, 2018. If you require alternate dates, please contact Mark Dennis of The Scientific Consulting Group, Inc. (SCG).

Check-in

When making a reservation, please provide your room and bedding preferences. The hotel will assign specific room types at check-in, based on availability. Please be advised that requests are not guaranteed. Check-in time is 4:00 p.m., and checkout time is 12:00 p.m.

Cancellations

If you need to cancel your reservation, please do so by 4:00 p.m. on the day prior to arrival, or you will be charged a no-show fee for 1 night on your credit card.

NIH Visitor Information

Information on visiting the NIH, campus maps, shuttle schedules, driving directions, security, and more can be found on the NIH Visitor Information page.​​

Minutes

Minutes are currently unavailable.

Attendees

Confirmed Speakers

Note: Additional speakers will be added to this list as they are confirmed.

Pre-meeting Workshop: Establishing a Research Career in Benign Urologic Conditions

Tamara Bavendam, M.D., Senior Scientific Officer, Division of Kidney, Urology, and Hematology Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD

Linda Brubaker, M.D., M.S., Health Sciences Clinical Professor, Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Reproductive Medicine, University of California, San Diego, CA

Karen Huss, Ph.D., R.N., Program Director, Division of Extramural Science Programs, National Institute of Nursing Research, Bethesda, MD

Adam Klausner, M.D., Associate Professor and Director of Neurourology, Female Urology, and Volding Dysfunction, Virginia Commonwealth University, Richmond, VA

Donna Mazloomdoost, M.D., Medical Officer, Gynecologic Health and Disease Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD

Lanay Mudd, Ph.D., Program Director, Division of Extramural Research, National Center for Complementary and Integrative Health, Bethesda, MD

Rahel Nardos, M.D., Adjunct Assistant Professor of Obstetrics and Gynecology, School of Medicine, Oregon Health & Science University, Portland, OR

Tracy Rankin, Ph.D., Deputy Director, Division of Kidney, Urology, and Hematology Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD

William Stuart Reynolds, M.D., M.P.H., Assistant Professor, Department of Urologic Surgery, Vanderbilt University Medical Center, Nashville, TN

Marcel Salive, M.D., M.P.H., Program Officer, Division of Geriatrics and Clinical Gerontology, National Institute on Aging, National Institutes of Health, Bethesda, MD

Leslie Subak, M.D., Professor of Obstetrics/Gynecology and Reproductive Sciences, Epidemiology and Biostatistics and Urology, University of California, San Francisco, San Francisco, CA

Vivian Sung, M.D., M.P.H., Associate Professor of Obstetrics and Gynecology, Women & Infants Hospital in Rhode Island and Brown Medical School, Providence, RI

Michael Wolfson, Ph.D., Program Director, Division of Discovery Science & Technology, National Institute of Biomedical Imaging and Bioengineering, Bethesda, MD

Main Scientific Session

Meryl Alappattu, D.P.T., Ph.D., Research Assistant Professor, Department of Physical Therapy, University of Florida, Gainesville, FL

Daniel Almirall, Ph.D., Assistant Professor, Survey Research Center, Faculty Associate, Population Studies Center, Institute for Social Research, University of Michigan, Ann Arbor, MI

Matt Barber, M.D., M.H.S., Professor of Obstetrics and Gynecology and Chair, Department of Obstetrics and Gynecology, Duke University School of Medicine, Durham, NC

Michael Chancellor, M.D., Director, Aikens Neurourology Research Center, Department of Urology, Beaumont Health, Dearborn, MI

Margot Damaser, Ph.D., Biomedical Engineering Department, Lerner Research Institute, Cleveland Clinic, Cleveland, OH

Damien Fair, Ph.D., PA-C, Associate Professor, Behavioral Neuroscience and Psychiatry, Associate Scientist, Advanced Imaging Research Center, Oregon Health & Science University, Portland, OR

Jeremy Heaton, M.D., Vice President, Medical Sciences, Astellas Pharma, Rotterdam, Netherlands

Michelle Seelig, M.D., M.S., Clinical Assistant Professor, Health Services, University of Washington, Seattle, WA

Janet Woodcock, M.D., Director, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, MD

Planning Committee

Tamara Bavendam, M.D., Senior Scientific Officer, Division of Kidney, Urology, and Hematology Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD

Lisa Begg, Ph.D., R.N., Senior Research Program Officer, Office of Research on Women’s Health, National Institutes of Health, Bethesda, MD

Carolyn Best, Ph.D., Director of Research, American Urological Association, Linthicum, MD

Linda Brubaker, M.D., M.S., Health Sciences Clinical Professor, Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Reproductive Medicine, University of California, San Diego, CA

Margot Damaser, Ph.D., Biomedical Engineering Department, Lerner Research Institute, Cleveland Clinic, Cleveland, OH

William Elwood, Ph.D., Health Scientist Administrator, Office of Behavioral and Social Sciences Research, National Institutes of Health, Bethesda, MD

Daniel Gossett, Ph.D., Program Director, Division of Kidney, Urology, and Hematology Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD

Karen Huss, Ph.D., R.N., Program Director, Division of Extramural Science Programs, National Institute of Nursing Research, Bethesda, MD

Donna Mazloomdoost, M.D., Medical Officer, Gynecologic Health and Disease Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD

Rahel Nardos, M.D., Adjunct Assistant Professor of Obstetrics and Gynecology, School of Medicine, Oregon Health & Science University, Portland, OR

Jenna Norton, M.P.H., Kidney and Urology Science Translation Program, Division of Kidney, Urology, and Hematology Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD

William Stuart Reynolds, M.D., M.P.H., Assistant Professor, Department of Urologic Surgery, Vanderbilt University Medical Center, Nashville, TN

Eric Rovner, M.D., Professor, Department of Urology, Pelvic Floor Medicine and Reconstructive Surgery, Medical University of South Carolina, Charleston, SC

Marcel Salive, M.D., M.P.H., Program Officer, Division of Geriatrics and Clinical Gerontology, National Institute on Aging, National Institutes of Health, Bethesda, MD

Abstracts

Attendees are invited to submit abstracts for posters to be presented at the end of the first day. Posters can be of two varieties:

  • Traditional—Presenting research that can improve our ability to individualize treatment for patients with UI. Posters do not need to focus on treatment of urinary incontinence.
  • Idea Generating—Building the case for a factor that might affect treatment outcomes and help target treatments, including why it should be considered in research.

The goal of the poster session will be to stimulate interdisciplinary thinking and create additional ideas to prepare for small group discussions the following day.

Following the poster session, there will be opportunities for small groups of individuals to go out to dinner to continue the discussions.

Submission Deadline

January 22, 2018, 5:00 p.m.

Submitting Abstracts

All abstracts must be submitted via email to Mark Dennis of The Scientific Consulting Group, Inc. at mdennis@scgcorp.com with “Individualizing Treatment for Urinary Incontinence” in the subject line. Abstract submissions should be no longer than 250 words (not including name and affiliation). Click here to download the template.

Formatting Requirements

Please follow the instructions below to format an abstract. (Note: Submissions will not be edited for spelling or grammar and will be accepted “as is.”)

  • The abstract should be an MS Word document typed single-spaced using Times New Roman font. Everything but the title should be in normal, 12-point font.
    • The abstract’s title should be Bold, 16-Point, Title Case font and should clearly represent the nature of the investigation.
    • On the line after the title, list the author’s first and last names, degree, affiliation, city, state, and country.
    • Separate multiple authors with a semicolon, and underline the primary author’s name (one primary author per abstract).
    • Use one blank line between the title and the body of the abstract and between paragraphs.
    • The abstract file name should follow this format: LastNameofprimary author_FirstWordOfTitle (e.g., Zucker_Effects).
  • Please ensure that your abstract is the correct length and use 1-inch margins.
  • Use of standard abbreviations is desirable (e.g., LUTS), as well as standard symbols for units of measure (e.g., kg, g, mg, mL, L, and %). Place any special or unusual abbreviations in parentheses after the full word the first time that it appears. Use numerals to indicate numbers except to begin sentences. Do not use subheadings (e.g., Methods, Results).
  • Simple tables or graphs may be included; however, they must fit within the designated abstract space of one page.

Poster Presentations

Posters will be displayed on 4-foot-high by 6-foot-wide poster boards. Pushpins and Velcro will be provided onsite. The recommended poster size is 3 feet by 5 feet.

Location

Line
  • Building 45
  • 45 Center Drive, NIH Campus
  • MD 20894
Webinar

Contacts

Line

Program Content

Tamara Bavendam, M.D., M.S.
NIDDK
T: 301-594-4733

Meeting Logistics

Mark Dennis
The Scientific Consulting Group, Inc.
T: 301-670-4990