U.S. Department of Health and Human Services
The Interface of Pancreatic Cancer Within Diabetes, Obesity and Inflammation: Research Gaps and Opportunities

The Interface of Pancreatic Cancer With Diabetes, Obesity and Inflammation: Research Gaps and Opportunities

10/12/2017 12:00 PM
10/12/2017 6:00 PM
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No

Program Content

Dana K. Andersen
Scientific Program Manager
NIDDK
T: 410-868-0638
E: andersendk@niddk.nih.gov

Meeting Logistics

Mark Dennis
The Scientific Consulting Group, Inc.
T: 301-670-4990
E: mdennis@scgcorp.com
Bethesda
 
National Library of Medicine, Lister Hill Center Auditorium

Event Details

Meeting Objectives

The purpose of The Interface of Pancreatic Cancer with Diabetes, Obesity, and Inflammation: Research Gaps and Opportunities Workshop is to explore the relationships of diabetes, obesity, and inflammation on the mechanisms, diagnosis and possible treatment of pancreatic ductal adenocarcinoma (PDAC). We plan sessions which will focus on the role of diabetes and altered intracellular metabolism on the development of PDAC, the mechanisms and diagnosis of PDAC-caused diabetes, the role of obesity as a risk factor and cause of PDAC, and the role of inflammation and immune mechanisms on the development and possible treatment of PDAC. Recommendations which arise from the workshop will inform possible future funding initiatives of NIDDK.

In addition to presentations from an international faculty of experts, poster presentations selected from submitted abstracts will also be presented. Abstract requirements can be found on the registration website. Attendance at the workshop is without charge, but registration is required.

This meeting is being held in conjunction with The 2017 Annual Mid-Atlantic Diabetes Research Symposium.

Registration Deadline

October 05, 2017​​​

Agenda

October 12, 2017

   
7:00 a.m. – 7:55 a.m. Registration
   
7:55 a.m. – 8:00 a.m.   Welcome and Introduction of Dr. Griffin P. Rodgers
James Abbruzzese, M.D., Duke University
Alvin Powers, M.D., Vanderbilt University
   
8:00 a.m. – 8:10 a.m. Introductory Remarks
Griffin P. Rodgers, M.D., Director, NIDDK
   
8:10 a.m. – 8:35 a.m. Overview Lecture: Diabetes and Anti-Diabetic Drugs as Risk Factors in Pancreatic Ductal Adenocarcinoma (PDAC), and the Rising Incidence of PDAC (Parallel to the Incidence of Obesity and Diabetes)
Peter Boyle, Ph.D., D.Sc., International Prevention Research Institute, Lyon, France
   
8:35 a.m. – 10:10 a.m. Session 1: The Role of Altered Energy Metabolism in PDAC
Moderators:
James Abbruzzese, M.D., Duke University
Alvin Powers, M.D., Vanderbilt University
   
  Possible Mechanisms of Increased Risk
Murray Korc, M.D., Indiana University School of Medicine
   
  Effects of Metformin on PDAC Risk
Stephen Pandol, M.D., Cedars-Sinai Medical Center
   
  Peptide and Other Mediators of PDAC
Seung Kim, M.D., Ph.D., Stanford University
   
  The Role of Altered Intracellular Metabolism in PDAC
Costas Lyssiotis, Ph.D., University of Michigan Medical School
   
  Integrating Information from Rodent Models to Human Disease
Alvin Powers, M.D., Vanderbilt University School of Medicine
   
10:10 a.m. – 10:30 a.m. Break
   
10:30 a.m. – 12:00 p.m. Session 2: PDAC as a Cause of Diabetes
Moderators:
Dana Andersen, M.D., NIDDK
Suresh Chari, M.D., Mayo Clinic
   
  Evidence for Possible Paraneoplastic Cause of Diabetes Mellitus (DM) in PDAC Patients
Suresh Chari, M.D., Mayo Clinic
   
  Possible Mechanisms of PDAC-Associated DM
Dana Andersen, M.D., NIDDK
   
  Possible Protein Biomarkers of PDAC-Associated DM, and Differentiation of PDAC-associated DM from Type 2 Diabetes Mellitus (T2DM)
Eithne Costello-Goldring, Ph.D., University of Liverpool, United Kingdom
   
  Inflammatory Biomarkers of PDAC-Associated DM
Carl Borrebaeck,Ph.D., Immunovia and Lund University, Sweden
   
12:00 p.m. – 1:00 p.m. Lunch and Poster Viewing
   
1:00 p.m. – 3:00 p.m. Session 3: Obesity as a Cause/Risk Factor for PDAC
Moderators:
Zobeida Cruz-Monserrate, Ph.D., The Ohio State University
Guido Eibl, M.D., University of California, Los Angeles
   
  The Risk of Obesity: Lessons from Bariatric Surgery
Bruce Wolfe, M.D., Oregon Health & Science University
   
  Possible Mechanisms of Obesity Risk for PDAC
Zobeida Cruz-Monserrate, Ph.D., The Ohio State University
   
  Laboratory Models of Obesity Effects on PDAC
Craig Logsdon, Ph.D., The University of Texas MD Anderson Cancer Center
   
  The Role of Visceral/Peri-Pancreatic Fat on Carcinogenesis
Guido Eibl, M.D., University of California, Los Angeles
   
  Microbiome Associations with Obesity and PDAC
William Fisher, M.D., Baylor University College of Medicine
   
3:00 p.m. – 3:20 p.m. Break
   
3:20 p.m. – 5:00 p.m. Session 4: Inflammation and the Immune System as a Cause/Mediator of PDAC
Moderators:
Aida Habtezion, M.D., M.Sc., Stanford University
Elizabeth Jaffee, M.D., Johns Hopkins University
   
  Role of Chronic Inflammation, Activated Pancreatic Stellate Cells, and Environmental Factors on PDAC Development
Aida Habtezion, M.D., M.Sc., Stanford University
   
  The Role of the Systemic Immune Environment on the Development of PDAC
Edgar Engleman, M.D., Stanford University
   
  The Role of Inflammation as a Mediator of Primary and Metastatic PDAC
Anil Rustgi, M.D., University of Pennsylvania
   
  The Role of Anti-Inflammatory Agents and Immunotherapy on PDAC Formation
Elizabeth Jaffee, M.D., Johns Hopkins University
   
5:00 p.m. – 5:30 p.m. Panel Discussion and Q&A
Moderators:
James Abbruzzese, M.D., Duke University
Alvin Powers, M.D., Vanderbilt University
   
5:30 p.m. Adjournment
   

Directions/Travel

Travel Arrangements

Participants are responsible for making their own travel arrangements. If you decide to extend your stay to take advantage of lower fares, DC-area attractions are only a short distance from the suggested hotels. For a list of local hotels, please view the Bethesda hotel map.

NIH Visitor Information

Information on visiting the NIH, campus maps, shuttle schedules, driving directions, security, and more can be found on the NIH Visitor Information page.

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Minutes

Minutes are currently unavailable.

Attendees

Attendees are currently unavailable.

Abstracts

Submitting Abstracts

Participants in the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Workshop, The Interface of Pancreatic Cancer with Diabetes, Obesity, and Inflammation: Research Gaps and Opportunities—are encouraged to submit abstracts of their research activities. In addition to an opportunity to present their research in a poster session, conference attendees will find additional career development and networking opportunities with other researchers.

Submission Deadline

September 21, 2017

Submitting Abstracts

All abstracts must be submitted via email to to Mark Dennis of The Scientific Consulting Group, Inc. at mdennis@scgcorp.com with "Interface of Pancreatic Cancer Abstract” in the subject line. Abstract submissions should be no longer than 250 words (not including name and affiliation). Click here to download the template.

Abstract Organization

Organize the body of the abstract as follows:

  • Statement of the purpose of the study/program/project
  • Statement of the methods used
  • Summary of the results presented in sufficient detail to support the conclusion
  • Statement of the conclusions reached

Formatting Requirements

Please follow the instructions below to format an abstract. (Note: Submissions will not be edited for spelling or grammar and will be accepted “as is.”)

  • The abstract should be an MS Word document typed single-spaced using Times New Roman font. Everything but the title should be in normal, 12-point font.
    • The abstract’s title should be Bold, 16-Point, Title Case font and should clearly represent the nature of the investigation.
    • On the line after the title, list the author’s first and last names, degree, affiliation, city, state, and country.
    • Separate multiple authors with a semicolon, and underline the primary author’s name (one primary author per abstract).
    • Use one blank line between the title and the body of the abstract and between paragraphs.
    • The abstract file name should follow this format: primary author’s LastName_FirstWordOfTitle (e.g., Zucker_Effects).
  • Please ensure that your abstract is the correct length and use 1-inch margins
  • Use of standard abbreviations is desirable (e.g., RBC), as well as standard symbols for units of measure (e.g., kg, g, mg, mL, L, and %). Place a special or unusual abbreviation in parentheses after the full word the first time that it appears. Use numerals to indicate numbers except to begin sentences. Do not use subtitles (e.g., Methods, Results).
  • Simple tables or graphs may be included; however, they must fit within the designated abstract space of one page.

Poster Presentations

Poster presentations will be displayed on 4-foot-high by 6-foot-wide poster boards. Pushpins and Velcro will be provided onsite.

Space will be available for up to 40 posters.

All presenters must register in advance for the conference.

Location

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  • Building 38A
  • NIH Campus
  • MD 20894
Webinar

Contacts

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Program Content

Dana K. Andersen
Scientific Program Manager
NIDDK
T: 410-868-0638
E: andersendk@niddk.nih.gov

Meeting Logistics

Mark Dennis
The Scientific Consulting Group, Inc.
T: 301-670-4990
E: mdennis@scgcorp.com