U.S. Department of Health and Human Services

Workshop on Best Practices for Studies of Diet and the Intestinal Microbiome

6/13/2017 12:00 AM
6/14/2017 12:00 AM
Yes
No

For questions concerning program content, contact:

Chris Lynch, Ph.D.
Director, Office of Nutrition Research
NIDDK/NIH
Phone: 301-827-3988
Email: christopher.lynch@nih.gov

To register, contact:

Nadine Kessler
USDA/ARS
Diet-Microbiome-Workshop@ars.usda.gov

Bethesda
 
Natcher Conference Center (Balcony B)

Event Details

Background

Many studies of the intestinal microbiome, whether in vitro, in animal models, or in humans report only minimal information on dietary components even though there is substantial evidence that diet modulates composition of the microbiota. Although many aspects of microbiome studies show improved quality control over time, this has not always extended to diet.

Meeting Objectives

The purpose of this workshop is to improve rigor and reproducibility in research on the colonic microbiome, identify important dietary information that should be reported and parameters to consider in design of studies, particularly for clinical studies on diet and the intestinal microbiome. A summary for the research community will be published in a peer-reviewed journal.

Organizing Committee

Christopher Lynch, Office of Nutrition/NIH
Cindy Davis, Office of Dietary Supplements/NIH
Robert Karp, NIDDK/NIH
David Klurfeld, Agricultural Research Service/USDA

Sponsors

USDA/Agricultural Research Service
International Life Sciences Institute

Registration Deadline

May 26, 2017 or until full.

RSVP to Diet-Microbiome-Workshop@ars.usda.gov via email with your name, affiliation and phone number.

Agenda

June 13, 2017

   
8:45 a.m. – 9:00 a.m. Welcome and Introductions

Session I

Characterization of dietary fibers and other nutrients that feed the microbiome

   
9:00 a.m. – 9:35 a.m. Keynote Talk: Chemical and physical characteristics of dietary fibers that affect their utilization by the gut microbiota and the host
George Fahey, University of Illinois
   
9:45 a.m. – 10:05 a.m. The broad range of structures of dietary fibers and their specificity to bacterial fermentation
Bruce Hamaker, Purdue University
   
10:15 a.m. – 10:35 a.m. Fiber-microbiome effects on health and disease: connecting real foods with specific microbial responses
Eric Martens, University of Michigan
   
10:45 a.m. – 11:00 a.m. Break

Session II

Animal Models

   
11:00 a.m. – 11:35 a.m. Keynote Talk: Diet-microbiota dynamics: leveraging animal models to hasten translatable discovery
Justin Sonnenburg
   
11:45 a.m. – 12:05 p.m. The role of gut microbial and host circadian rhythms in metabolic health and disease
Eugene Chang, University of Chicago
   
12:15 p.m. – 1:15 p.m. Lunch
   
1:15 p.m. – 1:35 p.m. Prebiotic action of food polyphenols on gut microbiota to alleviate obesity-linked inflammatory diseases
Andre Marette, University of Laval
   
1:45 p.m. – 2:05 p.m. Food additives and microbiota interactions in the etiology of intestinal inflammation
Benoit Chassaing, Georgia State University
   
2:15 p.m. – 2:35 p.m. Utility of Non-Rodent Models for Gastrointestinal Microbiome Research
Kelly Swanson, University of Illinois
   
2:45 p.m. – 3:00 p.m. Break
   
3:00 p.m. – 4:30 p.m. General Discussion on nutrients affecting microbiome and animal models
   

June 14, 2017

Session III

In Vitro Models

   
8:45 a.m. – 9:05 a.m. Culturing gut microbial ecosystems in vitro: using bioreactors as model systems
Emma Allen-Vercoe, University of Guelph
   
9:15 a.m. – 9:35 a.m. Effect of host diet on fecal fermentation outcomes
Devin Rose, University of Nebraska
   
9:45 a.m. – 10:15 a.m. General Discussion on in vitro models
   
10:15 a.m. – 10:30 a.m. Break

Session IV

Human Studies

   
10:30 a.m. – 11:05 a.m. Keynote Talk: Impact of diet on the human gut microbiome and its metabolome: relevance to health and disease
Gary Wu
   
11:15 a.m. – 11:35 a.m. What are the ideal fiber requirements for humans?
Stephen O’Keefe, University of Pittsburgh
   
11:45 a.m. – 12:05 p.m. Effect of diet on gut microbiota
Maria Saarela, VTT Finland
   
12:15 p.m. – 1:15 p.m. Lunch
   
1:15 p.m. – 1:35 p.m. Nutrients vs diets: using controlled feeding studies to evaluate diet-microbiome interactions in humans
Johanna Lampe, Fred Hutchinson Cancer Center
   
1:45 p.m. – 2:05 p.m. Beyond dietary fiber: foods, food additives, and supplements that alter gut bacteria
Joanne Slavin, University of Minnesota
   
2:15 p.m. – 2:35 p.m. Regulatory considerations in diet and microbiome studies
Barbara Schneeman, FDA (retired)
   
2:45 p.m. – 4:30 p.m. General Discussion: identification of critical dietary issues for design and reporting, terminology (e.g., fiber, prebiotics), research gaps that should be addressed in all studies of diet and gut microbiome, any issues remaining from previous discussions. Challenges in relating models to human situation.

Directions/Travel

Hotel Accommodations

Bethesda Marriott Hotel
5151 Pooks Hill Road
Bethesda, MD  20814

Attendees will be responsible for their own travel arrangements and expenses.

To reserve a room under the room block at the Bethesda - Pooks Hill Marriott, please use this URL:

https://aws.passkey.com/e/49039256

The room block will be available until April 20, 2017, or until full. Shuttle service to the NIH campus will be available.

For attendees who plan to stay for the George Vahouny Dietary Fiber Symposium on June 15-16, 2017, the same rate is available at the Bethesda North Marriott, 5701 Marinelli Rd., North Bethesda, MD. This hotel is two Metro stops north of the NIH campus on the Red Line.

Reservation Dates

Book arrival on Monday, June 12, 2017, and departure on Wednesday, June 14, 2017.

NIH Visitor Information 

Information on visiting the NIH, campus maps, shuttle schedules, driving directions, security, and more can be found on the NIH Visitor Information page.​

Minutes

Minutes are currently unavailable.

Attendees

Attendees are currently unavailable.

Abstracts

Abstracts are currently unavailable.

Location

Line
  • NIH Campus
  • Building 45
  • MD 20894
Webinar

Contacts

Line

For questions concerning program content, contact:

Chris Lynch, Ph.D.
Director, Office of Nutrition Research
NIDDK/NIH
Phone: 301-827-3988
Email: christopher.lynch@nih.gov

To register, contact:

Nadine Kessler
USDA/ARS
Diet-Microbiome-Workshop@ars.usda.gov