U.S. Department of Health and Human Services
Human Milk Composition Workshop Banner

Workshop on Human Milk Composition – Biological, Environmental, Nutritional, and Methodological Considerations

11/16/2017 12:00 AM
11/17/2017 12:00 AM
Yes
No

Program Content

Christopher Lynch, Ph.D.
Director, Office of Nutrition Research
NIDDK/NIH

Meeting Logistics

Kimberly Barch
Office of Nutrition Research
NIDDK/NIH

Charlemae Clarke
The Scientific Consulting Group, Inc.
T: 301-670-4990
Bethesda
 
Building 31/6C

Event Details

Background

The Federal Data Consortium on Pregnancy and Birth to 24 Months (P/B24) is a forum of Federal agencies to discuss needs for data on P/B24 populations and find opportunities for collaborative initiatives. Through this Data Consortium, high priority needs were articulated for current and expanded data on the composition of human milk for advancing public health initiatives. The U.S. Department of Agriculture’s (USDA) Agricultural Research Service (ARS) has maintained the food composition data in the USDA National Nutrient Database for Standard Reference (SR), including for human milk. However, these data are not current and the published literature do not provide adequate data to update the SR database for human milk. As such, ARS is collaborating with the Office of Disease Prevention and Health Promotion (ODPHP) of the U.S. Department of Health and Human Services (HHS) and the sponsoring agency for this workshop, the Office of Nutrition Research of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) of the National Institutes of Health (NIH) of HHS to first gather information 1) on the scientific needs for human milk composition (HMC) data, 2) on experimental designs for human milk collection, storage, and analysis, and 3) to develop a vision for establishing a research program to develop a HMC Database.

The focus of participation in this meeting is for Federal agencies with scientific expertise and/or interest in the composition of human milk. Non-federal participants include invited academic experts in human milk composition and experimental designs for human milk collection, storage, and analysis as well as database development. The role of non-federal invited experts is to assist the federal agencies in information gathering. As such, invited presentations should address the state of the science on the topic, which should be informed by personal research experiences, but not present the individual’s research program or study results.

The information presented through this meeting, including the list of attendees, will be published in a peer-reviewed journal. All attendees will be asked to provide appropriate disclosures.

Meeting Objectives

Through presentations, open discussion, and follow-up communications this workshop aims to

  • Present and discuss the scientific needs for data on human milk composition
  • Explore the current understanding of factors affecting milk composition and identify methodological challenges in human milk collection, storage, and analysis
  • Develop a vision to establish a research program to develop a human milk composition database

Organizing Committee

Office of Nutrition Research, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, U.S. Department of Health and Human Services

Christopher Lynch, Ph.D. (POC: christopher.lynch@nih.gov)

Office of Disease Prevention and Health Promotion, U.S. Department of Health and Human Services

Richard Olson, M.D., M.P.H.
Kellie Casavale, Ph.D., R.D. (POC: kellie.casavale@hhs.gov)

Nutrient Data Laboratory, Beltsville Human Nutrition Research Center, Agricultural Research Service U.S. Department of Agriculture

Pamela Pehrsson, Ph.D.
Xianli Wu, Ph.D.
Jaspreet Ahuja, M.S. (POC: jaspreet.ahuja@ars.usda.gov)

Registration Deadline

Please register to attend this workshop by October 25th, 2017, indicating whether you prefer to attend in-person or by webinar.

Non-federal attendance is by invitation only. Federal in-person attendance is space-limited. Priority will be given to individuals on the “Volunteer Interest/Expert Group” that includes staff from Federal agencies with scientific expertise and/or interest in the composition of human milk and academic experts in experimental designs for human milk collection, storage, and analysis as well as database development. For those who register to attend in-person, if space is not available, you will be contacted after registration closes and provided the webinar instruction.​

Agenda

November 16, 2017

   
9:00 a.m. – 9:15 a.m. Welcome from the Directors of the NIH Office of Nutrition Research and the USDA Human Nutrition Research Center
Christopher J. Lynch, Ph.D.
Director, Office of Nutrition Research
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institutes of Health, HHS

Naomi K. Fukagawa, M.D., Ph.D.
Director, Beltsville Human Nutrition Research Center (BHNRC)
Agricultural Research Center (ARS), USDA
   
9:15 a.m. – 9:25 a.m. Review of Agenda and Introduction of Speakers
Kellie O. Casavale, Ph.D., R.D.
Nutrition Advisor, Office of Disease Prevention and Health Promotion (ODPHP)
Office of the Assistant Secretary for Health (OASH), HHS

Session 1: Scientific Needs for Data on Human Milk

   
9:25 a.m. – 9:45 a.m. Perspectives from Federal Agencies
Kellie O. Casavale, Ph.D., R.D.
ODPHP, OASH, HHS
   
9:45 a.m. – 10:05 a.m. Perspectives from Non-federal Academic Researchers
Shelley McGuire, Ph.D.
Washington State University
   
10:05 a.m. – 11:05 a.m. Panel Discussion and Q/A with Attendees
Co-moderators: Pamela Pehrsson, Ph.D., Beltsville HNRC, ARS, USDA
Kellie O. Casavale, Ph.D., R.D., ODPHP, OASH, HHS

Panelists
Doug Balentine, Ph.D.
Food and Drug Administration

Mandy Brown Belfort, M.D., M.P.H.
Brigham and Women’s Hospital, Harvard Medical School

Bruce German, Ph.D.
University of California, Davis

Deborah Hayward, B.Sc. Hons, PG Dip
Health Canada
(participating remotely)

Erin Hines, Ph.D., D.A.B.T.
Environmental Protection Agency
James McClung, Ph.D.
Department of Defense
(participating remotely)

Shelley McGuire, Ph.D.
Washington State University

Cria Perrine, Ph.D.
Centers for Disease Control and Prevention

Catherine Spong, M.D.
Eunice Kennedy Shriver National Institute of Child Health and Human Development

Kathleen Rasmussen, Sc.D.
Cornell University
   
11:05 a.m. – 11:20 a.m. Break
   
11:20 a.m. – 11:30 a.m. Greetings from the Deputy Director of the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Catherine Y. Spong, M.D.
Deputy Director, NICHD, NIH, HHS

Session 2: Influential Factors on Human Milk Composition

   
11:30 a.m. – 11:50 a.m. Biology of Lactation and Human Milk (presenting remotely)
Margaret (Peggy) Neville, Ph.D., University of Colorado, Denver (Professor Emerita)
   
  Components of Human Milk
   
11:50 a.m. – 12:10 p.m. Lactation and Milk: The Roughs and the Smooths, Milk’s Constant and Dynamic Dimensions
Bruce German, Ph.D., University of California, Davis
   
12:10 p.m. – 12:30 p.m. Milk Proteins and Peptides: Bioactivity, Characterization, and Quantification
David Dallas, Ph.D., Oregon State University
   
12:30 p.m. – 12:50 p.m. Micronutrients in Human Milk: Implications for Recommended Intakes and Study Design
Lindsay H. Allen, Ph.D., USDA ARS Western Human Nutrition Research Center, University of California, Davis
   
12:50 p.m. – 1:50 p.m. Lunch Break

Session 2, Continued: Influential Factors on Human Milk Composition

   
  Components of Human Milk (continued)
   
1:50 p.m. – 2:10 p.m. Milk’s Non-Nutritive Components and Microbiome in Brief
Shelley McGuire, Ph.D., Washington State University
   
2:10 p.m. – 2:30 p.m. Milk Exosomes and RNA Cargos
Janos Zempleni, Ph.D., University of Nebraska-Lincoln
   
2:30 p.m. – 2:50 p.m. Panel Discussion and Q/A with Attendees
Moderator: Jaspreet Ahuja, M.S., ARS, USDA
   
2:50 p.m. – 3:05 p.m. Break
   
  Primary Factors Affecting Lactation and/or Human Milk Composition
   
3:05 p.m. – 3:25 p.m. Considerations of Time Intervals, Timing, and Time Frame in Sampling Human Milk
Laurie Nommsen-Rivers, Ph.D., R.D., IBCLC, University of Cincinnati
   
3:25 p.m. – 3:45 p.m. Variation in Human Milk Composition: Maternal Factors
Ardythe Morrow, Ph.D., M.Sc., University of Cincinnati Children's Hospital Medical Center
   
3:45 p.m. – 4:05 p.m. Factors that Affect Milk Composition: Maternal Diet
Kathleen Rasmussen, Sc.D., Cornell University
   
4:05 p.m. – 4:25 p.m. Environmental Chemicals in Breast Milk and Formula
Erin Hines, National Center for Environmental Assessment, EPA
   
4:25 p.m. – 4:45 p.m. Panel Discussion and Q/A with Attendees
Moderator: Jaspreet Ahuja, M.S., ARS, USDA
   
4:45 p.m. Adjourn
   

November 17, 2017

   
8:30 a.m. – 8:40 a.m. Greetings from the Deputy Director of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Gregory G. Germino, M.D.
Deputy Director, NIDDK, HHS
   
8:40 a.m. – 8:50 a.m. Review of Agenda and Introduction of Speakers
Kellie O. Casavale, Ph.D., R.D., ODPHP, OASH, HHS

Session 3: Considerations for Data Quality

   
  Sampling Strategies
   
8:50 a.m. – 9:10 a.m. Population-Based Sampling: Practice and Considerations
Amy Branum, Ph.D., M.S.P.H., NCHS, CDC, HHS
   
9:10 a.m. – 9:30 a.m. Practical Considerations in Sampling Human Milk Composition and Breast Milk Intake Volumes in the U.S.
Laurie Nommsen-Rivers, Ph.D., R.D., IBCLC, University of Cincinnati
   
  Considerations and Complexities in Standardizing Collection, Storage , and Analysis
   
9:30 a.m. – 9:45 a.m. Effects of Sampling, Sample Handling, and Analysis on Human Milk Composition Data: Retrospective View
Xianli Wu, Ph.D., C.F.S., ARS, USDA
   
9:45 a.m. – 10:00 a.m. Considerations and Complexities in Standardizing Milk Collection and Storage: Focus on Micronutrients
Lindsay H. Allen, Ph.D., USDA ARS Western Human Nutrition Research Center, University of California, Davis
   
10:00 a.m. – 10:15 a.m. Considerations and Complexities in Standardizing Milk Collection, Storage, and Analysis: Milk Lipids and Microbiome
Mark McGuire, Ph.D., University of Idaho
   
10:15 a.m. – 10:30 a.m. Considerations of Human Milk Analysis with Respect to Macronutrient Properties, Donor Milk Processing, and Milk Thickening
Jae Kim, M.D., Ph.D., University of California, San Diego
   
10:30 a.m. – 10:50 a.m. Panel Discussion and Q/A with Attendees
Moderator: Xianli Wu, Ph.D., C.F.S., ARS, USDA
   
10:50 a.m. – 11:10 a.m. Break

Session 4: Developing a Vision to Establish a Research Program for Human Milk Composition

   
11:10 a.m. – 11:25 a.m. Best Practices for Human Milk Content Measurements, Analysis, and Databasing
Shankar Subramaniam, Ph.D., University of California, San Diego
   
11:25 a.m. – 11:40 a.m. Human Milk in the Internet of Food: How, What, When, Where, Why
Matthew Lange, Ph.D., University of California, Davis
   
  Sharing Visions
   
11:40 a.m. – 11:55 a.m. Overview of the ECHO Program
Manjit Hanspal, Ph.D., ECHO Project, NIH, HHS
   
11:55 a.m. – 12:10 p.m. Nutrient Data Laboratory's Vision for the Human Milk Composition Database
Jaspreet Ahuja, M.S., ARS, USDA
   
12:10 p.m. – 12:25 a.m. A Vision for the Human Milk Composition Database of the United States and Canada
Ardythe Morrow, Ph.D., M.Sc., University of Cincinnati Children's Hospital Medical Center
   
12:25 p.m. – 12:40 p.m. Human Milk and Nutrition Research at NIH
Christopher J. Lynch, Ph.D., ONR, NIDDK, NIH, HHS
   
12:40 p.m. – 1:00 p.m. Panel Discussion and Q/A and Visions from Attendees
Moderator: Pamela Pehrsson, Ph.D., Beltsville HNRC, ARS, USDA
   
1:00 p.m. – 1:15 p.m. Next Steps for Development of a Research Program Proposal
Pamela Pehrsson, Ph.D., Beltsville HNRC, ARS, USDA
   
1:15 p.m. Adjourn

Directions/Travel

Hotel Accommodations

Bethesda Marriott Hotel
5151 Pooks Hill Road
Bethesda, MD  20814
Phone:  (301) 897-9400 or (800) 228-9290

Website:  http://www.bethesdamarriott.com
(More hotel information can be obtained from this website.)

Please be advised that meeting attendees are responsible for their own travel arrangements and costs.

Government Room Rate

A limited block of rooms for workshop participants has been reserved at the Bethesda Marriott Hotel. The rate is $201 per night for single occupancy, plus tax (13%). To reserve a hotel room at the group rate, call reservations at (800) 228-9290 or (301) 897-9400 and identify yourself as a member of the NIH-NIDDK Workshop Room Block or click on the link to book your group rate. The room block will be in effect at $201 per night only until Wednesday, October 25, or until full, whichever comes first. Any room reservations received after this date will be accepted on a space and rate-availability basis.

Reservation Dates

Book arrival on Wednesday, November 15, 2017, and departure on Friday, November 17, 2017.

Check-in

Please be certain that the hotel provides you with a confirmation number for your reservation. After October 25, 2017, the official room block will be released, and the hotel may charge significantly higher rates and may be sold out. When making a reservation, please provide your room and bedding preferences. The hotel will assign specific room types at check-in, based on availability. Please be advised that requests are not guaranteed. Check-in time is 4:00 p.m., and checkout time is 12:00 p.m.

Cancellations

If you need to cancel your reservation, please do so 48 hours prior to arrival, or you will be charged a no-show fee for 1 night on your credit card.

NIH Visitor Information

Information on visiting the NIH, campus maps, shuttle schedules, driving directions, security, and more can be found on the NIH Visitor Information page.​

Minutes

Minutes are currently unavailable.

Attendees

Attendees are currently unavailable.

Abstracts

Abstracts are currently unavailable.

Location

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  • Conference Room 6
  • 31 Center Drive
  • MD 20892
Webinar

Contacts

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Program Content

Christopher Lynch, Ph.D.
Director, Office of Nutrition Research
NIDDK/NIH

Meeting Logistics

Kimberly Barch
Office of Nutrition Research
NIDDK/NIH

Charlemae Clarke
The Scientific Consulting Group, Inc.
T: 301-670-4990